Sentences with phrase «in a large cohort of»

Studies also suggest a potential role for selected probiotics in atopic dermatitis prevention, and future studies will need to standardize the probiotic strain as well as amount used in a larger cohort of pregnant women in order to better assess these effects.

In conclusion, never or curtailed lactation was associated with an increased risk of incident maternal hypertension, compared with the recommended ≥ 6 months of exclusive or ≥ 12 months of total lactation per child, in a large cohort of parous women.

The new CNGB1 mutation in Phalenes and Papillons was discovered with six cases and 14 control dogs and confirmed in a larger cohort of dogs.

Khachaturian says a proper test of Roses» findings — using Roses» methods in a larger cohort of patients — has not yet been done.

«We hope to design a program that draws from these findings and more research on mindfulness meditation is needed in a larger cohort of mothers,» added Golfenshtein.

By evaluating the molecular changes that occur in large cohorts of ovarian cancer patients, the researchers were able to identify several lncRNAs that are linked to the disease.

Researchers expect the data presented in this study to fuel the formation of large national and international research consortiums to conduct comprehensive, systematic analysis of inherited (germline) genome data in large cohorts of uveal melanoma patients.

The earlier discovery of mutations in UBQLN2 gene, which causes ALS and ALS / dementia in children and adults, in the Siddique lab led to the screening of the UBQLN family of genes in a large cohort of patients with familial ALS, resulting in the identification of the UBQLN4 mutation.

Surprisingly, we found the same signature in large cohorts of women without the BRCA1 mutation and it was able to predict breast cancer risk several years before diagnosis.»

Interestingly, two recent reports that have catalogued recurrent focal deletions in large cohorts of human tumors and cancer cell lines.

The present study was aimed at identifying genetic modifiers modulating AAO in a large cohort of Italian FTD patients.

We have investigated the prevalence of this mutation in large cohort of almost 1000 patients with AML (3).

More recently, GLP - 1 response was evaluated in a large cohort of subjects of both sexes, with different degrees of BMI and ranging from NGT to T2DM.

First observed in B - cell lymphoma, recurrent mutations of epigenetic modifier genes have recently been identified in PTCL - NOS. 9 In the present study, we performed targeted sequencing of the main epigenetic modifier genes in a large cohort of Chinese PTCL - NOS patients.

In the first study (Klaassen et al., 2008) mutational analysis in a large cohort of 63 unrelated adult probands with LVNC and absence of other congenital heart anomalies was performed.

A third research initiative seeks to address a wide variety of other genetic questions of health and disease that are inherently answerable in large cohorts of blood donors and recipients.

Friday, Oct. 20, 5:30 - 5:50 p.m., South Hall B, South Building Featured Plenary Abstract: The contribution of rare variants, polygenic risk, and novel candidate genes to the hereditary risk of breast cancer in a large cohort of breast cancer families N. Li, Peter MacCallum Cancer Center, et al

Design: We collected standardised PSC subphenotypes in a large cohort of 3402 patients with PSC.

Our findings are potentially applicable to early disease detection, and future test development should focus on longitudinal sampling of the microbiota to monitor for changes in microbial diversity in a larger cohort of patients.

The LEAP study, designed and conducted by the ITN with additional support from FARE and led by Professor Gideon Lack at Kings College London, is the first randomized trial to prevent food allergy in a large cohort of high - risk infants.

In a large cohort of 21,930 Finnish men, there was a significant inverse association between Dietary Fiber intake and CHD, with a multivariate rela - tive risk of 0.84 for men in the highest quintile of intake (34.8 g / d) com - pared with the lowest quintile of intake (16.1 g / d)(Pietinen et al., 1996)(Table 7 - 2).

Fuchs and colleagues (1999) prospectively examined the relationship between Dietary Fiber intake and the risk of colon cancer in a large cohort of women.

CONCLUSIONS High total and animal protein intake was associated with a modest elevated risk of type 2 diabetes in a large cohort of European adults.

Prevalence of parietal cell antibodies in a large cohort of patients with autoimmune thyroiditis.

Examining the relationship between childhood health conditions and health service utilisation at school entry and subsequent academic performance in a large cohort of Australian children

Not exact matches

Millennials have not - so - quietly become the largest cohort in the Canadian workforce, but for many of those born in the 1980s and»90s, the cut - off to contribute to one's RRSP passes at the end of February without much fanfare.

The current cohort at the University of Alberta's MBA in natural resources, energy and environment is 10 % larger than the previous one, while the school's Fort McMurray MBA for oilsands workers is up nearly 35 %.

So, to see if his recommendations held any weight, Cramer checked in on the golf cohort, starting with Callaway, the maker of all things golf and the largest «pure play» in the industry.

Rieder notes they're now the largest cohort in history and are entering a phase in which they will be the biggest - spending segment of the economy.

Challenge number one was how hard it was to find a large number of research subjects working in similar jobs, who could divide into work - at - home and work - at - the - office cohorts, and who were willing to cooperate with the researchers over a long enough period of time.

Myers recently pointed out, according to CityLab, that the single largest cohort of millennials, those born in 1990, turned 25 last year.

This is especially true in large countries, such as China and India, where the sheer size of the millennial population is already having a global impact, but also here at home in Canada, where the millennial cohort is becoming an important strategic voting bloc.

This cohort — the Millennial generation — is the largest generational segment in American history and will benefit from one of the greatest wealth transfers in history over the coming years.

However the past 3 generations of our largest cohort Seed have averaged 40 % Chilean, highlighting an increasing amount of Chilean interest in the benefits of entrepreneurship.

A study published in 2000 by the ELCA revealed that of the cohort of newly minted pastors, 71 percent placed constraints upon where they could move due to the needs or desires of a spouse; 58 percent restricted their first call to a location in or near a large city; 36 percent were opposed to serving in a small congregation; and 32 percent were opposed to serving in a rural setting.

The process whereby the liberal Protestant colleges and universities were separated from their sponsoring churches in the period 1870 - 1910 may have been repeating itself during a comparable period, 1950 - 1990, among the very large cohort of universities and colleges that were founded as Catholic.

Chelsea's largest cohort of players currently abroad lies with the Red Devils (not that one from up in Manchester).

Last week, we posted to the site a group of four articles about a peer - reviewed study in the Journal of Neurosurgery showing that football helmet design affected concussion risk among a large group (or what scientists call a «cohort») of college football players.

Most studies of homebirth in other countries have found no statistically significant differences in perinatal outcomes between home and hospital births for women at low risk of complications.36, 37,39 However, a recent study in the United States showed poorer neonatal outcomes for births occurring at home or in birth centres.40 A meta - analysis in the same year demonstrated higher perinatal mortality associated with homebirth41 but has been strongly criticised on methodological grounds.5, 42 The Birthplace in England study, 43 the largest prospective cohort study on place of birth for women at low risk of complications, analysed a composite outcome, which included stillbirth and early neonatal death among other serious morbidity.

In particular, breastfeeding may be of concern because it has been shown to be associated with both child's use of antibiotics36, 37 and cow's milk allergy, although inconsistently so.38 In a large Finnish birth cohort, the median durations of exclusive and total breastfeeding were 1.4 months and 7.0 months, respectively, and the proportion of breastfed infants decreased from 95 % at the age of 1 month to 58 % at the age of 6 months.39 Another limitation is our reliance on pharmacy records, which provides only a rough estimation of drug use.

An UpToDate review on «Planned home birth» (Declercq and Stotland, 2015) stated that «Large cohort studies using intent - to - treat analysis of midwife - attended, planned, out - of - hospital birth of low - risk women in developed countries have reported reduced rates of cesarean birth, perineal lacerations, and medical interventions, and similar rates of maternal and early perinatal morbidity and mortality compared to planned hospital birth.

The research involved the largest population cohorts comprehensively examined to date for an association between breast feeding outcomes and place of birth in low risk pregnancies.

This also was found in a large, retrospective cohort study of 15,759 nulliparous women even in a group of women whose second stage progressed beyond 4 hours (29).

«For this large cohort of women who planned midwife - led home births in the United States, outcomes are congruent with the best available data from population - based, observational studies that evaluated outcomes by intended place of birth and perinatal risk factors.

Together, the results of the well - controlled observational studies20 - 23 (including ours), the analysis of cohorts without social patterning of breastfeeding (eg, in the Pelotas cohort), 24 and the large randomized trial25 suggest that confounding does not account fully for the observed association of breastfeeding with later cognition.

Similarly, in another large cohort, the rate of VBAC was higher among women undergoing induction of labor at 39 weeks compared with expectant management (73.8 % versus 61.3 %, P <.001)(104).

Second, in relation to the larger follow - up cohort (N = 12, see 1st paragraph of results), women in Mature Group 2 were below the median in both insulin secretion and insulin sensitivity, whereas women in Mature Group 1 were above the median for these measures.

We found a direct association between never or curtailed lactation and incident hypertension in a large, prospective cohort of parous women.

The baby - boomers have turned out to be the most privileged of cohorts our country has produced when common sense would suggest that this extraordinarily large group, born in the wake of the 1945 peace, would be disadvantaged by their size.

Commenting on the study, ESMO spokesperson Dirk Arnold, MD, PhD, from Instituto CUF de Oncologia in Lisbon, Portugal, said «this large population - based cohort - control study impressively confirms the hypothesis of an association of colorectal polyps with diets and other life - style factors.