Sentences with phrase «in a single gene makes»

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The disease results from a single mutation in the gene that codes for one of the protein chains that make up the hemoglobin molecule.
The team found that a mutation in a single pair of nucleotides in the gene causes seed coat permeability — that is, a change in one pair out of the approximately 1 billion base pairs that make up the soybean genome.
In 1993, Brunner discovered a predisposition to violence in a single Dutch family carrying a mutation in the gene which makes monoamine oxidase A (MAOA), another enzyme vital for regulating neurotransmitter levels in the braiIn 1993, Brunner discovered a predisposition to violence in a single Dutch family carrying a mutation in the gene which makes monoamine oxidase A (MAOA), another enzyme vital for regulating neurotransmitter levels in the braiin a single Dutch family carrying a mutation in the gene which makes monoamine oxidase A (MAOA), another enzyme vital for regulating neurotransmitter levels in the braiin the gene which makes monoamine oxidase A (MAOA), another enzyme vital for regulating neurotransmitter levels in the braiin the brain.
When a single gene exists in the ancestral mutation, that would have made for higher levels of enzyme expression, would have messed up with sensory function.
So, I'll just say a little more about why yeast; which is, over the decades, yeast molecular biologists have devised so many powerful tools that allow you to make very precise changes in yeast, in their DNA; exquisite control, where you can change a single base that you want in a particular place, you can put a whole gene in, take a whole gene out, swap genes etc..
But then a gene on a single chromosome mutated in a way that made any individual that inherited it male.
In other words, type 2 diabetes could never make it into the Finnish Disease Heritage, where a change in a single gene is decisivIn other words, type 2 diabetes could never make it into the Finnish Disease Heritage, where a change in a single gene is decisivin a single gene is decisive.
Last autumn Jean Weissenbach and Marc Lathrop came up with a new type of genetic map which makes it possible to map most single genes in «months instead of years», according to Nigel Spurr, a cancer researcher and gene mapper at the Imperial Cancer Research Fund.
The researchers, led by Dr Charles Wondji, used a wide range of methods to narrow down how the resistance works, finding a single mutation in the GSTe2 gene, which makes insects break down DDT so it's no longer toxic.
Companies selling Bt seeds hope to avoid that in part by designing plants that make more than one Bt toxin, but this strategy may not work if resistance to several toxins is tied to a single gene, says Tabashnik, who is now at the University of Arizona.
A year ago we started thinking, why don't we select a single family with an interesting disease and see whether studying a smaller group of related individuals makes it possible to identify the genes involved in that disease.
Robert Friedman of the J. Craig Venter Institute in San Diego, California, another AHTEG member who was singled out, similarly bristles at being criticized for encouraging experts to contribute to the online forum, especially given that opponents of gene drives sometimes make «pretty fishy» statements there.
A way of silencing genes using specially designed molecules of RNA — like DNA but made of only a single strand — that target the message molecules in cells and tell them not to make a certain protein
The tool, in particular, could be ideal for both these diseases, scientists think, because each is caused by mutations in a single gene that makes hemoglobin, the protein in the red blood cells that transports oxygen throughout the body.
Earlier cases of resistance were largely due to mutations in single genes — trump cards that immediately made for invincible parasites.
Early on, researchers realized they could use CRISPR - Cas9 to make single cuts in a specific gene pretty easily.
What's more, inherited diseases can arise from a problem with one gene (a simple example is sickle - cell anemia, a condition caused by defects in a single gene that makes the hemoglobin protein), or from interactions among a range of genetic variations as well as, frequently, environmental stresses.
We are using a new technique, called single cell RNA sequencing, to isolate thousands of single neurons from human brain tissue, study all the genes that are expressed in each individual cell, and make cell - to - cell comparisons between normal, early stage and late stage AD.
The Hopkins scientists report that the loss of a single gene in kidney cancer cells causes them to stop making mitochondria, the tiny powerhouses of the cell that consume oxygen to generate energy.
The disease is genetically simple, being characterised by a single mutation in the HBB gene; this simplicity has made it an attractive target for gene editing therapies.
In DNA, each protein is encoded by a gene (a specific sequence of DNA nucleotides that specify how a single protein is to be made).
Gene targeting makes it possible to study the effects of single genes, including those that don't occur naturally in mice.
by Bryant Frazer Not just the best Gene Kelly film, and not just the best movie musical ever made, Singin» in the Rain is a genuine national treasure — a single text proving for posterity what a wondrous thing the Hollywood studio system could be when it was firing on all cylinders.
Dr. Wu inserted a gene that makes a single faulty enzyme in protein metabolism.
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