Not exact matches
The disease results from a
single mutation
in the
gene that codes for one of the protein chains that
make up the hemoglobin molecule.
The team found that a mutation
in a
single pair of nucleotides
in the
gene causes seed coat permeability — that is, a change
in one pair out of the approximately 1 billion base pairs that
make up the soybean genome.
In 1993, Brunner discovered a predisposition to violence in a single Dutch family carrying a mutation in the gene which makes monoamine oxidase A (MAOA), another enzyme vital for regulating neurotransmitter levels in the brai
In 1993, Brunner discovered a predisposition to violence
in a single Dutch family carrying a mutation in the gene which makes monoamine oxidase A (MAOA), another enzyme vital for regulating neurotransmitter levels in the brai
in a
single Dutch family carrying a mutation
in the gene which makes monoamine oxidase A (MAOA), another enzyme vital for regulating neurotransmitter levels in the brai
in the
gene which
makes monoamine oxidase A (MAOA), another enzyme vital for regulating neurotransmitter levels
in the brai
in the brain.
When a
single gene exists
in the ancestral mutation, that would have
made for higher levels of enzyme expression, would have messed up with sensory function.
So, I'll just say a little more about why yeast; which is, over the decades, yeast molecular biologists have devised so many powerful tools that allow you to
make very precise changes
in yeast,
in their DNA; exquisite control, where you can change a
single base that you want
in a particular place, you can put a whole
gene in, take a whole
gene out, swap
genes etc..
But then a
gene on a
single chromosome mutated
in a way that
made any individual that inherited it male.
In other words, type 2 diabetes could never make it into the Finnish Disease Heritage, where a change in a single gene is decisiv
In other words, type 2 diabetes could never
make it into the Finnish Disease Heritage, where a change
in a single gene is decisiv
in a
single gene is decisive.
Last autumn Jean Weissenbach and Marc Lathrop came up with a new type of genetic map which
makes it possible to map most
single genes in «months instead of years», according to Nigel Spurr, a cancer researcher and
gene mapper at the Imperial Cancer Research Fund.
The researchers, led by Dr Charles Wondji, used a wide range of methods to narrow down how the resistance works, finding a
single mutation
in the GSTe2
gene, which
makes insects break down DDT so it's no longer toxic.
Companies selling Bt seeds hope to avoid that
in part by designing plants that
make more than one Bt toxin, but this strategy may not work if resistance to several toxins is tied to a
single gene, says Tabashnik, who is now at the University of Arizona.
A year ago we started thinking, why don't we select a
single family with an interesting disease and see whether studying a smaller group of related individuals
makes it possible to identify the
genes involved
in that disease.
Robert Friedman of the J. Craig Venter Institute
in San Diego, California, another AHTEG member who was
singled out, similarly bristles at being criticized for encouraging experts to contribute to the online forum, especially given that opponents of
gene drives sometimes
make «pretty fishy» statements there.
A way of silencing
genes using specially designed molecules of RNA — like DNA but
made of only a
single strand — that target the message molecules
in cells and tell them not to
make a certain protein
The tool,
in particular, could be ideal for both these diseases, scientists think, because each is caused by mutations
in a
single gene that
makes hemoglobin, the protein
in the red blood cells that transports oxygen throughout the body.
Earlier cases of resistance were largely due to mutations
in single genes — trump cards that immediately
made for invincible parasites.
Early on, researchers realized they could use CRISPR - Cas9 to
make single cuts
in a specific
gene pretty easily.
What's more, inherited diseases can arise from a problem with one
gene (a simple example is sickle - cell anemia, a condition caused by defects
in a
single gene that
makes the hemoglobin protein), or from interactions among a range of genetic variations as well as, frequently, environmental stresses.
We are using a new technique, called
single cell RNA sequencing, to isolate thousands of
single neurons from human brain tissue, study all the
genes that are expressed
in each individual cell, and
make cell - to - cell comparisons between normal, early stage and late stage AD.
The Hopkins scientists report that the loss of a
single gene in kidney cancer cells causes them to stop
making mitochondria, the tiny powerhouses of the cell that consume oxygen to generate energy.
The disease is genetically simple, being characterised by a
single mutation
in the HBB
gene; this simplicity has
made it an attractive target for
gene editing therapies.
In DNA, each protein is encoded by a
gene (a specific sequence of DNA nucleotides that specify how a
single protein is to be
made).
Gene targeting
makes it possible to study the effects of
single genes, including those that don't occur naturally
in mice.
by Bryant Frazer Not just the best
Gene Kelly film, and not just the best movie musical ever
made, Singin»
in the Rain is a genuine national treasure — a
single text proving for posterity what a wondrous thing the Hollywood studio system could be when it was firing on all cylinders.
Dr. Wu inserted a
gene that
makes a
single faulty enzyme
in protein metabolism.