«Our findings contribute further understanding of the biology of psychiatric and neurological diseases and whether autoantibodies
detected in a subgroup of patients can trigger psychiatric disorders.
He added: «The only positive and continuous result was
in the subgroup of patients who took more exercise, which means regular exercise at least twice a week, plus the wine consumption.
Intensive blood pressure (BP) control reduced the risk of cardiovascular (CV) events by 21 % compared with standard BP
control in a subgroup of patients from the ACCORD - BP trial who had type 2...
The combination did not show any deterioration in health - related QoL compared to either treatment alone,
even in the subgroup of patients experiencing grade 3/4 adverse events.»
Thus, histamine intolerance seems to be acquired mostly through the impairment of DAO activity caused by gastrointestinal diseases or through the inhibition of DAO, but the high interindividual variations in the expression of DAO in the gut and the association of SNPs in the DAO gene with gastrointestinal diseases provide evidence for a genetic
predisposition in a subgroup of patients with histamine intolerance (27).