Anything that results
in an abnormal accumulation of material in the ear canal often can not get out due to the canal pointing upward and thus inhibiting drainage.
This defect impairs the breakdown of complex molecules resulting
in abnormal accumulation of this macromolecules in the cells of the peripheral and central nervous system.
Share Pei fever can also lead to Amyloidosis, an enzyme deficiency results
in abnormal accumulations of amyloid proteins, causing liver or kidney failure.
Not exact matches
Aside from the feat of answering the longstanding question of how the lymph system arises, understanding how it forms and develops can provide important insights into disease, from metastasis to the
abnormal accumulation of lymph fluids, particularly
in the wake of surgery to remove cancerous tumors.
Chronic alcohol consumption causes
abnormal fat
accumulation in liver cells (steatosis) and liver fibrosis, which can lead to hepatitis, cirrhosis, and sometimes liver cancer.
They found LM22A - 4 reduces
abnormal protein
accumulation, delays nerve cell degeneration, and improves motor skills
in the animals.
LM22A - 4 treatment reduced the
accumulation of
abnormal proteins
in the striatum and cortex — brain regions affected
in Huntington's disease.
Other approaches target the
abnormal accumulation of the protein tau
in neurofibrillary tangles.
It may also bring about advances
in diagnosing diseases like Alzheimer's and multiple sclerosis, both of which involve
abnormal iron
accumulation in the brain.
Amyloid — an
abnormal protein whose
accumulation in the brain is a hallmark of Alzheimer's disease — starts accumulating inside neurons of people as young as 20, a much younger age than scientists ever imagined, reports a surprising new Northwestern Medicine study.
Amyloid — an
abnormal protein whose
accumulation in the brain is a hallmark of Alzheimer's disease — starts accumulating inside neurons of people as young as 20, a much younger age than scientists ever imagined.
The problem with making blood stem cells proliferate outside the body is that the artificial growth gives rise to an
accumulation of
abnormal proteins
in a part of the cell called the endoplasmic reticulum, ER.
In the current study, Dr. Santambrogio and her colleagues looked for abnormal accumulations of proteins in the synovial fluid (which bathes the joints) and blood of patients with JI
In the current study, Dr. Santambrogio and her colleagues looked for
abnormal accumulations of proteins
in the synovial fluid (which bathes the joints) and blood of patients with JI
in the synovial fluid (which bathes the joints) and blood of patients with JIA.
Both types of dementia (memory and language) can be caused by an
accumulation of beta - amyloid, an
abnormal toxic protein
in the brain.
Several human neurodegenerative diseases, including Alzheimer's, Parkinson's and Huntington's disease but also aging, are linked to an
accumulation of
abnormal and aggregated proteins
in cells.
«Our results indicate that exercise may slow the progression of Parkinson's disease by turning on the protective gene DJ - 1 and thereby preventing
abnormal protein
accumulation in brain,» Freed said.
Lewy bodies (
accumulation of
abnormal alpha - synuclein A protein
in the human brain that is associated with the development of Parkinson's.
Alzheimer's disease, the most common form of dementia, is characterized by the
accumulation of plaques (composed of amyloid - beta protein) and fibrous tangles (composed of
abnormal tau)
in brain cells called neurons.
Figure 2:
Abnormal accumulation of the FGFR - TACC fusion protein (red)
in glioblastoma stem cells isolated from a primary human glioblastoma with fused FGFR - TACC genes.
Crigler - Najjar Syndrome is a rare genetic liver disease (incidence around 1/1 000 000 births) associated with the
abnormal accumulation of bilirubin — a yellow pigment produced by the liver —
in all the body's tissues, particularly the brain tissues.
NAFLD is an imbalance between the uptake and removal of lipids
in hepatocytes, which leads to
abnormal triglyceride
accumulation, or steatosis.
A group of disorders that includes both Alzheimer's and FTD, tauopathies are characterized by the
abnormal accumulation of the protein Tau
in neurons.
(3,18; cf. 19,20) Even
in visceral fat, it has recently emerged that the obesity - driven rise
in inflammation and insulin resistance is associated with an
abnormal accumulation of senescent cells, albeit senescent endothelial cells rather than adipocytes.
However, it is widely accepted that a central event
in AD pathogenesis is the
abnormal accumulation of Aβ and its related toxins, either due to increased production or to deficits
in clearance mechanisms [52, 53].
We report here that
in vitro generated DS neural cells have
abnormal metabolism of amyloid - β (Aβ) manifested by increased secretion and
accumulation of Aβ granules of Aβ42 pathological isoform with upregulated expression of the APP gene.
We are particularly interested
in how aging - related pathways, such as sirtuins, modulate the processes underlying the
abnormal accumulation and microglial activation.
The relatively small number of such cells
in a youthful tissue is so small as to be harmless, but after decades of
accumulation, the number becomes large enough that their
abnormal metabolic state begins to pose a threat to surrounding, healthy tissues.
Abnormal accumulation of aluminum has been found
in the brains of people with Alzheimer's disease, and when aluminum is injected into the brains of laboratory animals, the animals develop a neurological disease similar to Alzheimer's.
Congestion, an
abnormal accumulation of blood,
in the lower extremities is no good thing.
Edema is an
abnormal accumulation of fluid
in a body part.
Bloat (dilation) is a condition of an
abnormal accumulation of air, fluid, and / or foam
in the stomach and can occur with or without the twisting (volvulus) of the stomach.
Since the major culprit
in diabetes is the
abnormal accumulation of glucose
in the blood, a canine diabetic diet is centered on reducing the carbohydrate content of food.
Hepatic lipidosis: an
abnormal accumulation of lipids
in the liver which leads to liver failure.
Hydrocephalus: a condition where there is an
abnormal accumulation of fluid
in the ventricles of the brain.
Anasarca: a condition where neonatal puppies have an
abnormal accumulation of fluids
in their tissues.
This condition is caused by
abnormal accumulation of air
in the stomach.
This can lead to an
abnormal accumulation of excessive copper
in the liver known as copper storage hepatopathy, leading to hepatic dysfunction and scarring (cirrhosis).
According to PetPlace.com, nephrotic syndrome
in dogs is a disorder that involves a combination of factors: protein
in the dog's urine, a low blood protein level, high cholesterol and
abnormal fluid
accumulation known as edema anywhere
in the pet's body.
The cause of microcytosis is not known; however, decreased serum iron concentration, normal to increased ferritin concentration, and
accumulation of stainable iron
in the liver suggest that microcytosis is associated with
abnormal iron metabolism rather than absolute iron deficiency.
(2) To limit further liver damage by preventing
accumulation of copper and free radicals (3) To support liver cell regeneration (4) To prevent or minimize possible complications, such as
abnormal brain function caused by passage of toxic substances from the liver to the blood (called hepatic encephalopathy) and the buildup of fluid
in your dog's abdomen (called ascites).
The iodine is taken up by the active (
abnormal) thyroid tissue, but not by any other tissues, resulting
in a selective local
accumulation of radioactive material
in the
abnormal tissues.
Cough, exercise intolerance, dyspnea (difficulty breathing),
abnormal lung sounds, hepatomegaly (enlargement of the liver), syncope (temporary loss of consciousness due to poor blood flow to the brain), ascites (fluid
accumulation in the abdominal cavity),
abnormal heart sounds, death
Patients with hydrocephalus have
abnormal accumulation of cerebrospinal fluid (CSF)
in the ventricles, or cavities, of the brain.
The exact mechanisms leading to the
abnormal accumulation of air
in respiratory tissues are not well understood.
Known as bloat, distended abdomen is an
abnormal accumulation of fluid
in the abdomen.
Foul breath because of the
abnormal accumulation of nitrogenous wastes
in the blood unable to be eliminated because of kidney failure
Edema is an
abnormal accumulation of fluid
in the cavities and intercellular spaces of the body.
Abnormal anatomy and placement of the liver, ascites (fluid
accumulation in the abdomen) and shunt location not only confirms the condition, but can also help to differentiate between the two different types of dog liver shunts.
A surprising number of cats have problems with constipation (
abnormal accumulation of feces and difficulty defecating), and similar but more serious conditions such as obstipation (complete obstruction of the colon by feces) and megacolon (damaged nerves and muscles
in the colon causing an inability to defecate).