Sentences with phrase «in acute phase»

Results indicate that CT and IPT do not differ in the treatment of depression in the acute phase and beyond.

In the acute phase of the disease, blood transfusions are often necessary due to severe anemia.

Many of the symptoms present in the acute phase may return along with lameness, anemia, swollen limbs and blood clotting problems.

Signs of Ehrlichia in dogs can occur 1 - 3 weeks after the bite of an infected tick, and in the acute phase of the disease, symptoms may last up to a few weeks.

In the acute phase of an injury, inflammation is of primary concern.

Rest from any aggravating activities and apply cold therapy whilst in the acute phase when the foot or ankle is painful and inflamed.

The application of ice to an injury, in the acute phase can substantially decrease the extent of the damage.

But despite the importance of these T - cell responses against HIV, especially in the acute phase of infection, they ultimately fail to control HIV's effects.

Earlier time points may have offered an indication of liver function in the acute phase [50], but persistent hepatic effects were unapparent by these tests.

«This explanation was favored because the typical route of Ebola virus transmission is through infectious body fluids from individuals in the acute phase of the disease, when they are most symptomatic.»

Antibodies can therefore protect at two levels: in the initial phase, by blocking sporozoites, and in the acute phase of the disease, by blocking the infected red blood cells.

The two drugs in Truvada, emtricitabine and tenofovir, are effective antiretroviral treatments, but trials have shown that viruses exposed to lower doses in the acute phase of infection can become resistant, said meeting attendees.

Strikingly, subsequent results showed that this miRNA - like fragment existed in acute phase but disappeared in recovery phase of EVD survivors.

The monkeys were treated early in the acute phase of their disease, soon after they were infected, whereas people in the studies had all been infected for many months or even years.

«Many of the current Phase I trials for spinal cord injury are run in the acute phase, which is right after injury.

Not exact matches

The company's lead product candidate, dilanubicel (NLA101), is currently being evaluated in two ongoing Phase 2 clinical trials in adult and pediatric patients with hematologic malignancies undergoing an allogeneic transplant and adult patients receiving high dose chemotherapy for Acute Myeloid Leukemia.

Many central banks, especially during the most acute phases of the crisis, also employed policies known as «credit easing,» which involves purchases of private sector assets in certain credit markets that are important to the functioning of the financial system but are temporarily impaired.

For the second time in 5 months, Juno Therapeutics has put a clinical hold on a Phase II trial of JCAR015 in adult patients with relapsed or refractory B - cell acute lymphoblastic leukemia due to patient deaths.

So far Greece's turmoil hasn't spread to other countries in the 18 - country currency union, the way it did back in the crisis» most acute phase between 2010 and 2012.

Dipasquale also said that cayenne should only be taken when an ulcer is in a healing or calm phase, but never when it is acute or inflamed.

After seeing promising results in phase 1 of the Pediatric Leukemia Adoptive Therapy (PLAT - 02) trial with 93 percent of patients with relapsed or refractory acute lymphoblastic leukemia (ALL) achieving complete initial remission, researchers at Seattle Children's are continuing their quest to improve the experimental therapy and reduce the rate of relapse, which is about 50 percent.

While death rates from the acute phase of cardiovascular events have decreased, the disease burden remains high in the increasing number of survivors, which is especially important for those affected at a young age.

Symptoms in travellers with Zika included rash (88 %) and fever (80 %) during the acute phase, and about half complained of muscle or joint pain or headaches.

Acute HIV infection corresponds to a phase right after contamination, when the virus replicates rapidly but is temporarily contained by a strong immune response, resulting in often - dismissed flulike symptoms.

Adipose tissue produces several proinflammatory, procoagulant, and acute - phase molecules in direct proportion to adiposity.

The acute phase response to infection and inflammation induces alterations in iron homeostasis that reduce iron supplies to pathogens.

A Phase III Randomized Trial for Newly Diagnosed High Risk B - precursor Acute Lymphoblastic Leukemia (ALL) Testing Clofarabine (IND # 73789, NSC # 606869) in the Very High Risk Stratum

A Phase 3 Open - label, Multicenter, Randomized Study of ASP2215 versus Salvage Chemotherapy in Patients with Relapsed or Refractory Acute Myeloid Leukemia (AML) with FLT3 Mutation

A Phase 3 Open - Label Randomized Study of Quizartinib (AC220) Monotherapy Versus Salvage Chemotherapy in Subjects with FLT3 - ITD Positive Acute Myeloid Leukemia (AML) Refractory To or Relapsed After First - line Treatment With or Without Hematopoietic Stem Cell Transplantation (HSCT) Consolidation

A Phase I Study of DS - 3201B in Subjects with Acute Myelogenous Leukemia (AML) or Acute Lymphocytic Leukemia (ALL)

There is increasing evidence in humans and laboratory animals for biologically - based sex differences in every phase of drug addiction including acute reinforcing effects, transition from occasional to compulsive use, withdrawal - associated negative affective states, craving, and relapse.

A Phase 1/2, Multicenter, Open - label Study of FT - 2102 as a Single Agent and in Combination with Azacitidine or Cytarabine in Patients with Acute Myeloid Leukemia or Myelodysplastic Syndrome with an IDH1 Mutation

A Phase 1, Multicenter, Open - Label, Safety Study of AG - 120 or AG - 221 in Combination with Induction Therapy and Consolidation Therapy in Patients with Newly Diagnosed Acute Myeloid Leukemia with an IDH1 and / or IDH2 Mutation

A Biomarker - Directed Phase 2 Trial of SY - 1425, a Selective Retinoic Acid Receptor Alpha Agonist, in Adult Patients with Acute Myeloid Leukemia (AML) or Myelodysplastic Syndrome (MDS)

A Phase I - II Randomized Trial of a Combination of Nintedanib / Placebo in Combination with Induction Chemotherapy for Patients with Refractory or First Relapse Acute Myeloid Leukemia

Research The acute phase response and soman - induced status epilepticus: temporal, regional and cellular changes in rat brain cytokine concentrations.

CT - 011, developed by Israel - based Curetech Ltd, is also being tested in phase II trials in metastatic melanoma, colorectal cancer in combination with chemotherapy, advanced renal cell and prostate cancers, as well as in acute myeloid leukemia.

A Phase 3, Multicenter, Randomized, Open - Label Study of Guadecitabine (SGI - 110) versus Treatment Choice in Adults with Previously Treated Acute Myeloid Leukemia

Final results of a cohort from a phase II monotherapy trial of quizartinib in acute myeloid leukemia patients showed that more than half of patients 60 years of age and older who harbored an internal tandem duplication in the FMS - like tyrosine kinase 3 had a composite complete remission.

Bornhäuser M, Kienast J, Trenschel R, et al Reduced - intensity conditioning versus standard conditioning before allogeneic haemopoietic cell transplantation in patients with acute myeloid leukaemia in first complete remission: a prospective, open - label randomised phase 3 trial.

AST - VAC1 (antigen - presenting autologous dendritic cells) is an autologous cancer immunotherapy with promising efficacy and safety data from a Phase 2 study in Acute Myeloid Leukemia (AML).

These structural changes occur in two steps: in the early phase (within 72 hours of acute ischemia), serine proteases and activated matrix metallo - proteases act to degrade the extracellular matrix resulting in expansion of the infarcted area.

It is important to note that the level of virus found in these fluids is several orders of magnitude lower than that found during the initial, acute, phase of infection.

In summary, our results point to both a significant «vacation effect» that benefitted all groups, and a suppression of stress - related responses and immune function related to acute - phase wound healing and inflammation.

Temporal changes in synaptic proteins in hippocampal slices indicated acute synaptic loss, followed by synapse formation and maintenance phases.

Her interests in the laboratory included strategies to eradicate HIV - 1, with a focus on the HIV - 1 reservoir in HAART - treated patients from acute or chronic phase infection.

She is the Protocol Chair for RV329: African Cohort Study; RV262, an international Phase I DNA / MVA HIV vaccine trial; and for RV398, an upcoming Phase I trial of the VRC01 broadly neutralizing monoclonal antibody administered in acute HIV infection in East Africa and Thailand.

Ponatinib was not found to show better or worse outcomes in in blast - crisis phase (BC)- CML, or in Philadelphia chromosome — positive acute lymphoblastic leukemia (Ph + ALL).

Human inter-α-inhibitor family in inflammation: simultaneous synthesis of positive and negative acute - phase proteins

IL - 6 has been shown to be involved in diverse physiological processes such as T - cell activation, induction of immunoglobulin secretion, initiation of hepatic acute phase protein synthesis, and stimulation of hematopoietic precursor cell proliferation and differentiation.