Not exact matches
As a balanced vasodilator, pimobendan dilates both veins and arteries resulting
in a reduction
in preload and
afterload.
Pimobendan is proven to decrease preload and
afterload, and this,
in combination with pimobendan's inotropic properties, may result
in a reduction
in cardiac size and filling pressures
in dogs with significant cardiac remodelling secondary to MMVD.
Stroke volume is defined as the amount of blood ejected from the left ventricle during systole and is a product of preload (the amount of blood entering the heart),
afterload (the amount of resistance
in the vasculature to the flow of blood from the heart), and contractility (the heart's ability to contract).
In general, ACE inhibitors lower the blood pressure (decrease
afterload) and decrease salt and water retention.