Warren D. Shlomchik, M.D. Yale University Memory T cells for improved immune reconstitution and GVL
in allogeneic hematopoietic stem cell transplantation
Not exact matches
In that program, we focused on treating children with both malignant and genetic conditions with generally
allogeneic hematopoietic stem cell transplantation.
One promising solution to increase long - term overall survival has been
in the area of
allogeneic hematopoietic stem cell transplantation (HCST).
Use of a lower dose of rabbit anti — T - lymphocyte globulin (ATLG) was superior to a higher dose
in children with hematologic malignancies undergoing
allogeneic hematopoietic stem cell transplantation (HSCT) from an unrelated donor, according to the results of a study published
in Lancet Oncology.
Low - Dose ATLG Prevents GVHD
in Pediatric Hematologic Malignancies: A newly published randomized phase III study of pediatric patients showed lower doses of rabbit anti — T - lymphocyte globulin (ATLG) was superior to a higher dose
in children with hematologic malignancies undergoing
allogeneic hematopoietic stem cell transplantation from an unrelated donor.
These
allogeneic cells have the potential to participate
in immune surveillance for breast or other cancers as observed
in clinical
hematopoietic stem cell transplantation.