Sentences with phrase «in apical»

Results: We show that P. falciparum extracellular vesicles (PfEVs) are enriched in proteins found within the exomembrane compartments of infected erythrocytes such as Maurer's clefts (MCs), as well as the secretory endomembrane compartments in the apical end of the merozoites, suggesting that these proteins play a role in parasite - host interactions.

Discovered that Kv7 / M / KCNQ - type K + channels are present in the perisomatic region but not in the apical dendrites of hippocampal pyramidal neurons (Hu et al., J. Neuroscience, 2007).

Morphologic evidence for spatially clustered spines in apical dendrites of monkey neocortical pyramidal cells.

Serotonin induces excitatory postsynaptic potentials in apical dendrites of neocortical pyramidal cells.

ENaC is expressed in the apical membrane of salt - absorbing epithelia of kidney, distal colon, and lung.

He is presently studying the role of specific defects in apical vesicle trafficking in the etiology of neonatal diarrhea syndromes in human.

«The defect in the mandibular left first molar does not have the appearance of a cavity preparation made by a dentist in that the defect is shallow, is nonretentive and is not extended in an apical direction interproximally.

Not exact matches

NextWave Ventures Makes Strategic Investment in Proprietary Artificial Intelligence Platform with Apical.

«In traditional risk assessment, we consider apical endpoints and apply safety factors to determine what would be an acceptable level of exposure.

Luan and colleagues began by mapping the distribution of CTL1 in Arabidopsis, and found that it was ubiquitous but was highest where auxin was highest: in the growing tips, in the vascular tissue, and in the «apical hook» that seedlings lead with as they push up through the soil.

These organoids form all of the cell types present in human intestine, but they grow as cysts surrounded by thick extracellular matrix gels with their «apical» cell surface (which is normally exposed to the content of the gut) facing an enclosed lumen.

Following this, cells undergo shape changes and organise around a central lumen, with their apical (top) surfaces facing the lumen, the basal (bottom) surfaces interacting with the underlying tissue and the lateral (side) surfaces in close contact with the neighbouring cells.

For example, up - regulated influx transporters (OCT3 and OCTN1) localized at the apical membranes of Sertoli cells could mediate the transport of the drug compound 9 from the lumen into the basolateral compartment of Sertoli cells, where the up - regulated efflux transporters (ABCB1 / p - glycoprotein, ABCB8, ABCB9, ABCC5, and ABCC10) could then transport the drug out of Sertoli cells against a concentration gradient, resulting in enhanced efficiency of recovery upon cessation of treatment.

These proteins have been reported to be localized and functional at the apical membranes of Sertoli cells as well as other organs (43; reviewed in Refs.

There are also differences in the affinity of different transporters for specific drugs: for example, the high - affinity transporters OCT1 and / or OCTN2 are functional at the basolateral membrane of rat Sertoli cells, whereas the low - affinity transporters OCT3 and / or OCTN1 are functional at the apical membrane (43).

Mutations in TFL1 and Dt1 both result in the shoot apical meristem (SAM) switching from vegetative to reproductive state to initiate terminal flowering and thus produce determinate stems.

Isotropic acto - myosin dynamics promote organization of the apical cell cortex in epithelial cells.

At 11 days after sowing (DAS), the shoot apical meristem (SAM) in the wild type had transitioned to an IM and initiation of the first axillary BMs were just visible (Supplemental Figure 2A).

Abstract We discovered that a subset of satellite cells in skeletal muscle are self - renewing stem cells that give rise to myogenic progenitors through asymmetric apical - basal cell divisions.

Brassinosteroids regulate organ boundary formation in the shoot apical meristem of Arabidopsis

grassy tillers1 promotes apical dominance in maize and responds to shade signals in the grasses

These five types of stem cells are described in the Discovery database as a general dental pulp stem cell population, which includes the following stem cell types: dental pulp stem cell (DPSCs), stem cells from exfoliated deciduous teeth (SHED), periodontal ligament stem cells (PDLSCs), stem cells from apical papilla (SCAP), and dental follicle progenitor cells (DFPCs).

Infection with human rhinovirus, the most common cause of asthma exacerbation in adults and children, was restricted to ciliated cells and resulted in ciliated cell apical sloughing and goblet cell hyperplasia, replicating hallmarks of cytopathology observed in vivo.

In particular we are interested to unravel the mechanisms that ensure the maintenance of the apical membrane when exposed to physical stress, e. g. during morphogenesis of epithelial tissues, or when exposed to light stress in photoreceptor cells, using Drosophila and zebrafish as model organismIn particular we are interested to unravel the mechanisms that ensure the maintenance of the apical membrane when exposed to physical stress, e. g. during morphogenesis of epithelial tissues, or when exposed to light stress in photoreceptor cells, using Drosophila and zebrafish as model organismin photoreceptor cells, using Drosophila and zebrafish as model organisms.

The apical domain can be further subdivided into spatially and functionally distinct regions, nicely seen in photoreceptor cells, where the apical domain is further subdivided into the rhabdomere and the stalk membrane (green and magenta, respectively, in Fig.

lls and resulted in ciliated cell apical sloughing and goblet cell hyperplasia, replicating hallmarks of cytopathology observed in vivo.

Title: Mouse inscuteable induces apical - basal spindle orientation to facilitate intermediate progenitor generation in the developing neocortex Authors: Postiglione M P, Jüschke C, Xie Y, Haas GA, Charalambous C, Knoblich JA Date: 2011 Publication Details: Neuron 2011 Oct 20; 72 (2): 269 - 284

In the Intestine Chip, the epithelium forms villi - like projections lined by polarized epithelial cells that undergo multi-lineage differentiation similar to that of intestinal organoids, however, these cells expose their apical surfaces to an open lumen and interface with endothelium.

The malaria vaccine FMP2.1 / AS02A is a recombinant protein (FMP2.1) based on apical membrane antigen 1 (AMA1) from the 3D7 clone of P. falciparum, formulated in the Adjuvant System AS02A.

The effects of apical meristem damage on growth and defences of two Acacia species in the Negev Desert.

In the mammalian eye, apical - basal polarity is essential in PR cells for the transmission of light signals from the retina to the braiIn the mammalian eye, apical - basal polarity is essential in PR cells for the transmission of light signals from the retina to the braiin PR cells for the transmission of light signals from the retina to the brain.

Prominin - 2 is a cholesterol - binding protein associated with apical and basolateral plasmalemmal protrusions in polarized epithelial cells and released into urine.

Müller cell apical processes appear to be lost in regions lacking adherens junctions in these mice, as demonstrated by absent or reduced CD44 labeling and by electron microscopy.

Through its F - actin - severing activity, the microvillar actin - binding protein villin drives both apical microvilli disassembly in vitro and in vivo and promotes lamellipodial extension.

A, Polymerase chain reaction amplification of a 196 — base pair (bp) apical membrane antigen 1 (AMA1) fragment of Plasmodium falciparum in Egyptian mummies.

Spermatogenesis in both species starts with spermatogonial stem cells located in a specific position of the tubule, attached to the apical end in fly and to basement membrane in mice, which move and progress into later stages of cell types in one direction, towards the basal end of the testis tubule in fly and towards the lumen in mice.

aRG cells are highly elongated, extending a basal process all the way to the pial surface of the developing brain and an apical process that remains in contact with the ventricular surface (Fig. 1).

In response to extracellular matrix signalling, these cells undergo epithelialization and create an apical surface in contact with a cavity, a fundamental event for all subsequent developmenIn response to extracellular matrix signalling, these cells undergo epithelialization and create an apical surface in contact with a cavity, a fundamental event for all subsequent developmenin contact with a cavity, a fundamental event for all subsequent development.

Apical localisation of crumbs in the boundary cells of the Drosophila hindgut is independent of its canonical interaction partner stardust.

Internalization of POS is observed in a single optical y - axis projection (< 1 µm) of pigmented iPS - RPE cells labelled with the apical cell surface marker ATP1B1 (red).

In all cases, sinusoidal fluid - jet stimuli from different orientations suggested the underlying channels were opened not directly by deflections of the hair bundle but by deformation of the apical plasma membrane.

Sweet taste receptors in rat small intestine stimulate glucose absorption through apical GLUT2.

Helicobacter pylori VacA disrupts apical membrane - cytoskeletal interactions in gastric parietal cells.

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Enzymes are stored in zymogen granules within the acinar cell in the presence of pancreatic secretory trypsin inhibitor (PSTI) and are released at the apical surface directly into the duct system.

Isovolumetric relaxation time was evaluated using pulsed wave Doppler in a left apical 5 - chamber view.

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Reversibility of apical dendritic retraction in the rat medial prefrontal cortex following repeated stress