Sentences with phrase «in aplastic»
A common trait in aplastic anaemia, regardless of whether it is inherited or acquired, is the presence of short telomeres.
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«Study of gene mutations in aplastic anemia may help optimize treament.»
In aplastic anemia, the body's immune system appears to destroy these stem cells.
A common trait in aplastic anemia, regardless of whether it is inherited or acquired, is the presence of short telomeres.
Not exact matches
She died in 1934 due to aplastic anemia, which is caused by prolonged exposure to radiation.
Dr. Kimball, 93, who had lived for years on Chicago's North Shore before moving to Florida in 1982 after his retirement, died Friday, Dec. 27, of aplastic anemia.
Ernest Robbins Kimball, M.D., 93, a pediatrician and pioneer in the scientific documentation of the medical and psychological benefits of breastfeeding, passed away Dec. 27, 2002 of complications resulting from aplastic anemia.
Rocco Bavuso, left, 22, of Bayside, who was diagnosed with aplastic anemia, meets Christian Verholen, 32, his marrow doner, on May 8, 2018, at the annual Celebration of Life Dinner of North Shore University Hospital's Don Monti Bone Marrow and Stem Cell Transplantation Program at Crest Hollow Country Club in Woodbury.
«Indeed, the treatment [with telomerase] significantly prevents mortality from aplastic anemia, and lengthens the telomeres in the blood and in bone marrow,» say the authors.
If so, says Grover Bagby, a hematologist who directs the Oregon Cancer Center at the Oregon Health Sciences University in Portland, further work to decipher the protein's exact function could shed light on how to treat a much larger population of patients with leukemia, certain other forms of cancer, and aplastic anemia.
«In the group that was not treated with the gene therapy, the majority of the animals die from aplastic anemia, and they also die much sooner.»
One of them was used to reproduce acquired aplastic anemia: due to various types of damage, some of the stem cells die, and those that remain need to divide more frequently in order to maintain the production of blood cells; as a result of so many divisions, the telomeres shorten and the disease appears.
«We provide proof - of - concept that the telomerase based treatment -LRB-...) has a therapeutic effect on the type of aplastic anemia caused by short telomeres,» the authors state in an article in the journal Blood, with Christian Bär among them as the first author, as well as Juan Manuel Povedano.
The study, appearing in the New England Journal of Medicine, could lead to tailor - made treatment plans for aplastic anemia patients as part of the emerging precision medicine movement.
Alemtuzumab is in clinical trials for treating aplastic anemia.
In certain types of aplastic anemia, lymphocytes are responsible for attacking the bone marrow stem cells.
It is still an investigational therapy, in combination with other medications, for treating aplastic anemia and other forms of bone marrow failure.
Researchers are currently studying MMF in combination with other medicines for treating aplastic anemia.
«In the group that was not treated with the gene therapy, the majority of the animals die from aplastic anaemia, and they also die much sooner.»
One of them was used to reproduce acquired aplastic anaemia: due to various types of damage, some of the stem cells die, and those that remain need to divide more frequently in order to maintain the production of blood cells; as a result of so many divisions, the telomeres shorten and the disease appears.
This work, published in «Blood», was carried out by the CNIO Telomeres and Telomerase Group The treatment is based on the transport of the telomerase gene to the bone marrow cells using gene therapy, a completely new strategy in the treatment of aplastic anaemia
INHERITED AND ACQUIRED Aplastic anaemia can be caused by inherited mutations in about thirty genes (known to date), several of which are involved in preserving the telomeres.
«Indeed, the treatment [with telomerase] significantly prevents mortality from aplastic anaemia, and lengthens the telomeres in the blood and in bone marrow,» say the authors.
These advances make it possible for half - identical bone marrow transplants to be used in nonmalignant diseases, such as aplastic anemia, lupus, and sickle cell anemia.
«We provide proof - of - concept that the telomerase based treatment -LRB-...) has a therapeutic effect on the type of aplastic anaemia caused by short telomeres,» the authors state in an article in the journal Blood, with Christian Bär among them as the first author, as well as Juan Manuel Povedano.
This is what happens in people with lupus, rhumatoid arthritis, juvenile diabetes and some aplastic anemias.
In older adult pets, diseases of the immune system and bone marrow that cause blood loss due to loss of clotting ability (thrombocytopenias), destroy red blood cells directly (autoimmune hemolytic anemias) or prevent their formation (aplastic anemias) are a less common but significant cause.
High prolonged levels of oestrogen in the body can cause aplastic anaemia.
In addition to multiple sclerosis and motor neuron disease, this could include severe burns, Parkinson's disease, deafness, coma, aplastic anemia, aortic surgery, blindness, Alzheimer's disease, bacterial meningitis, loss of limbs, loss of speech, HIV infection (occupational), and heart valve replacement.
Aplastic anemia is a type of anemia in which the body stops producing red blood cells altogether.