Sentences with phrase «in asthma development»
The researchers adopted a multi-step approach to understanding asthma development, by investigating the non-enzymatic and the enzymatic ways that oxidative stress in asthma development is managed by the body.
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In the asthma study, we found increased odds among asthma patients of asthma hospitalizations, emergency department visits and a medication used for mild asthma attacks with higher unconventional natural gas development activity, compared to those with lower activity.
Even if a state's concussion safety law does cover community - based, private sports programs, very few states have enacted laws that cover all aspects of youth sports safety, such as requiring more broad - based safety training for coaches in first - aid, CPR, and the use of an AED, and the development and implementation of an Emergency Action Plan (EAP) to be triggered in case of medical emergencies, such as a cardiac event (e.g. sudden cardiac arrest), asthma attack, allergic reaction to a bee sting, or heat stroke, and environmental emergencies (lighting, tornado, or an excessively high heat index).
That's because breast milk — custom - made nourishment specially formulated by Mother Nature — offers so many benefits: It boosts your baby's immune system, promotes brain development, and may reduce your child's risk of Sudden Infant Death Syndrome (SIDS) as well as diabetes, some types of cancer, obesity, high cholesterol, and asthma later in life.
Although findings are mixed regarding associations between breastfeeding and the development of asthma and atopic disease in childhood, exclusive breastfeeding for the first 6 months of life has multiple known benefits and remains the recommendation of ACOG for all women who do not have physical or medical conditions that prohibit breastfeeding.
«If the breast milk bacteria discovered in this study were important for the development of the immune system, its addition to infant formula could decrease the risk of allergies, asthma and autoimmune diseases,» conclude the authors.
And not only do these nutrients play a useful role in your baby's healthy development, they also help prevent conditions like asthma and — in later life — help protect the heart.
«Previous studies have linked intake of high fructose corn syrup sweetened beverages with asthma in school children, but there is little information about when during early development exposure to fructose might influence later health,» said Sheryl L. Rifas - Shiman, MPH, a study lead author and senior research associate at Harvard Medical School and Harvard Pilgrim Health Care Institute.
«Our study shows that the fraction of particulate pollution that is coarse contributes to the development and severity of asthma in children,» says Corinne Keet, M.D., M.S., Ph.D., associate professor of pediatrics at the Johns Hopkins University School of Medicine, and the study's first author.
«We did this study to understand whether, in addition to PM2.5, coarse particulate matter contributes to asthma development and morbidity,» said Corinne A. Keet, MD, PhD, lead study author and associate professor of pediatric allergy and immunology at Johns Hopkins University School of Medicine.
Understanding the role the brain plays in conditions linked to inflammation — such as asthma, arthritis, cardiovascular disease and depression — will help in the development of new treatments to combat them, says Slavich.
The outcomes of this work open new avenues of research with the goal of elucidating the biological mechanisms underlying asthma in relationship with environmental exposures and to promote the development of new therapies.
This study opens new avenues of research aiming at integrating genomic and epigenomic data together with environmental exposures in order to elucidate the physio - pathological mechanisms underlying asthma and to promote the development of new therapies.
Our data suggest that exposure to STAT6 - IP has the potential to modulate long - term responses to allergens and microbial antigens implicated in the development of asthma,» said Brian J. Ward, M.D., a researcher involved in the work and associate professor from McGill University Health Centre, Research Institute in Montreal, Quebec, Canada.
Researchers at the Medical College of Wisconsin (MCW) have linked a specific protein to the development of post-viral infection asthma, which is the first step in generating a novel type of asthma therapy designed to prevent development of post-viral asthma in young children.
In addition, the seven - year URECA results confirm previous research linking development of childhood asthma to recognized risk factors such as prenatal exposure to tobacco smoke and maternal stress and depression.
Research demonstrates that blocking the action of two pro-inflammatory molecules significantly reduces symptoms of allergic asthma in mice, which could lead to development of a new treatment for people with a severe form of the condition.
Together with the inflammatory cells in the skin and mucous membranes, the «mast cells,» IgE antibodies are responsible for certain allergic diseases, such as asthma and hay fever, for example, and are also partly responsible for the development of neurodermatitis.
The oxidative stress and resulting inflammation appear to play a role in the development of atherosclerosis (blocked arteries) and can make other health conditions worse, especially for people with existing cardiac or lung conditions including asthma.
To date, the present study is the largest to investigate the association between levels of long - chain omega - 3 and omega - 6 fatty acids in the blood and subsequent development of asthma and other allergic diseases.
«There are several diseases, like certain types of cancer and asthma, where stiffness of the cell is known to be linked to the phenotype of the disease,» says Ming Guo, the Brit and Alex d'Arbeloff Career Development Assistant Professor in MIT's Department of Mechanical Engineering.
The researchers discovered that this Treg cell type plays a decisive role in the development and manifestation of allergic asthma.
Natural killer cells serve important roles in clearing non-type 2 inflammatory cells, so identification of a defect in NK cell function in severe asthma provides a window for the development of new therapeutic approaches.
Although the immune mechanisms implicated in the development of childhood asthma are not fully understood, some studies seem to suggest that the BCG vaccine, used in tuberculosis prevention, may have a protective effect on childhood asthma.
«We know that mothers» exposure to air pollution during pregnancy can affect lung development of their babies and lead to subsequent respiratory disorders, including asthma, although little is known about whether timing of the exposure is important to consider,» said lead author Yueh - Hsiu Mathilda Chiu, ScD, from the Department of Pediatrics at Icahn School of Medicine at Mount Sinai in New York.
Both obesity and asthma are serious public health problems at historically high levels in the U.S., the authors note, and many researchers have associated obesity with the development of asthma and with an increased risk for asthma exacerbations.
Dr Alexander Mazein, lead author of the study from the European Institute for Systems Biology and Medicine, commented: «In - depth understanding of asthma means redefinition of asthma subtypes based on the mechanisms that lead to the development of the disease.
The AsthmaMap is the first integration of the known processes involved in the development of asthma based on a consensus view of asthma.
Asthma is a type I allergic disease, and IgE has an important role in the development of asthmaAsthma is a type I allergic disease, and IgE has an important role in the development of asthmaasthma (19).
OVER THE PAST FEW YEARS, researchers have come to realize the importance of the human microbiome — the roughly 100 trillion microorganisms that live in our gut — in everything from health and digestion to asthma and brain development.
The compound targets the product of a gene deCODE has shown to play an important role in the development of asthma.
Reykjavik, ICELAND, December 17, 2004 — deCODE genetics (Nasdaq: DCGN) today announced the signing of an agreement under which it will conduct a Phase II information - rich clinical trial next year of a third - party compound as part of a drug development program in asthma.
Dr. Freeman's laboratory focuses on the identification and function of T cell costimulatory and coinhibitory pathways in regulating T cell activation and application of this knowledge to the development of more effective immunotherapies for cancer, infections, asthma, and autoimmune diseases.
High IgE levels are a key clinical measure of an aggravated immune sensitivity to certain particles in the environment — the basis of atopy (allergies) and an important predisposing factor to the development of asthma.
For asthma, the gut microbiome in early life is important for proper immune system development and dysbiosis in early life leads to an increased risk for asthma.
«Development of asthma in inner - city children: Possible roles of MAIT cells and variation in the home environment.
Stephen Alexander, UK - Cannabinoid receptors, transporters, endocannabinoid turnover, hydrogen sulphide turnover Arthur Christopoulos, Australia (GPCRs Liaison)- G protein - coupled receptors; analytical pharmacology; allosteric modulation; biased agonism; drug discovery; neuropharmacology John Cidlowski, USA (NHRs Liaison)- Glucocorticoid receptor signaling; apoptosis and the immune system Anthony P. Davenport, UK (Chair Evolving Pharmacology, GPCRs Liaison) Doriano Fabbro, Switzerland - Kinases and their biology, kinase inhibitors, drug discovery, pharmacology of drugs (kinase inhibitors) in the indication oncology, biology of oncology Kozo Kaibuchi, Japan Yoshikatsu Kanai, Japan - Transporters, amino acid signals, epithelial function, cancer biology Francesca Levi - Schaffer, Israel - eosinophils and mast cells as effector cells in allergic inflammation: characterization of new receptors / ligands, hypoxia / angiogenesis and eosinophils, asthma, atopic dermatitis, allergic rhinitis, immunopharmacological modulation of allergic diseases by bispecific recombinant antibodies, bacteria interactions with eosinophils and mast cells, the allergic effector unit, mast cell derived tumors: new antibody based treatment, the allergic inflammation and the resolvome, non IgE - mediated mast cell activation in diseases Eliot H. Ohlstein, USA (Editor)- Drug discovery and development, urogenital biology, cardiovascular / metabolic medicine John A. Peters, UK (LGICs Liaison) Alex Phipps, UK - Oncology, Clinical Pharmacology, Biologics and Immunotherapy Joerg Striessnig, Austria (VGICs Liaison)- Physiology, pharmacology and pathophysiological role of voltage-gated calcium channels
deCODE has isolated a gene which plays an important role in the development of asthma.
Halapi E., Hakonarson H. Recent development in genomic and proteomic research for asthma.
In 2007, he was awarded a prestigious National Career Development Fellowship to undertake translational studies in the epigenetic regulation of the immune cell signaling molecules in human asthma under the mentorship of K. Mark Ansel, Ph.D., at UC San Francisco, where he was appointed adjunct assistant professor in the Department of Medicine in 200In 2007, he was awarded a prestigious National Career Development Fellowship to undertake translational studies in the epigenetic regulation of the immune cell signaling molecules in human asthma under the mentorship of K. Mark Ansel, Ph.D., at UC San Francisco, where he was appointed adjunct assistant professor in the Department of Medicine in 200in the epigenetic regulation of the immune cell signaling molecules in human asthma under the mentorship of K. Mark Ansel, Ph.D., at UC San Francisco, where he was appointed adjunct assistant professor in the Department of Medicine in 200in human asthma under the mentorship of K. Mark Ansel, Ph.D., at UC San Francisco, where he was appointed adjunct assistant professor in the Department of Medicine in 200in the Department of Medicine in 200in 2009.
One of the principal goals in the development of new methods for treating asthma is therefore to identify non-steroidal drugs that can effectively control the inflammatory response underlying asthma symptoms.
The results of the Immune Tolerance Network's (ITN) «Learning Early About Peanut» (LEAP), discussed on February 23, 2015 at the American Academy of Allergy, Asthma & Immunology Annual Meeting and published in the New England Journal of Medicine, demonstrate that consumption of a peanut - containing snack by infants who are at high - risk for developing peanut allergy prevents the subsequent development of allergy.
Dr. Holtzman conducts research on the role of infection in the development and progression of chronic airway diseases such as asthma and COPD.
The study, «Perinatal air pollution exposure and development of asthma from birth to age 10 years», was published in the European Respiratory Journal: http://erj.ersjournals.com/
As a medical doctor who specializes in gut health, studies confirm what I've seen in my practice: The Mediterranean diet can reduce the burden or prevent development of cardiovascular disease, breast cancer, depression, colorectal cancer, diabetes, obesity, asthma, erectile dysfunction, and cognitive decline.
In addition to obesity, these chemicals have been linked to asthma, attention - deficit hyperactivity disorder, breast cancer, type 2 diabetes, altered reproductive development, and male fertility issues.
Free radicals are thought to play a large role in the development of many well - known chronic and degenerative diseases like atherosclerosis, cancer, Alzheimer's Disease, asthma, and autoimmune conditions like rheumatoid arthritis.
The World Health Organization and United Nations this year concluded: «Exposure to E.D.C.s during fetal development and puberty plays a role in the increased incidences of reproductive diseases, endocrine - related cancers, behavioral and learning problems, including A.D.H.D., infections, asthma, and perhaps obesity and diabetes in humans.»
Mounting research indicates the bacterial colonies residing in your gut may play key roles in the development of cancer, asthma, allergies, obesity, diabetes, autoimmune diseases and even brain, behavioral and emotional problems like ADHD, autism and depression.
The results provide more evidence that environmental factors, such as diet, can influence the development of asthma, which has increased dramatically in recent years in westernized countries where high - fat diets are common.