Sentences with phrase «in behavioral tests»

In mouse models in which the endogenous Smn1 gene has been knocked out and human versions of SMN2 have been swapped in, the Isis therapy — a so - called «antisense oligonucleotide» — delivered to the mouse central nervous system (CNS) increased the expression of full - length SMN protein in motor neurons, improved muscle strength in behavioral tests and extended the rodents» median lifespan from 16 days to 26 days3.

Dr. Carlezon and his group were the first to report that a class of drugs called kappa - opioid receptor (KOR) antagonists has antidepressant, anti-anxiety, and anti-stress effects in their behavioral tests.

«In both behavioral tests used in this study, the mice need to control the paw movement,» explains Yi Li, M.D., a Henry Ford neuroscientist and lead author of the study.

These mice also went on to exhibit a range of depressive symptoms in behavioral tests.

Not exact matches

Real - life behavioral psychology: Students have to make a major life decision in the middle of taking the most stressful math test they've ever had.

In her research, behavioral and learning scientist Marily Oppezzo tested groups of people as they brainstormed creative uses for everyday objects.

Working with a third - party clinical testing group, Neba studied 275 children and adolescents ranging in age from 6 to 17 years old, all of whom exhibited signs of attention or behavioral concerns.

Also there is evidence of molecular mechanisms in the cell membranes that can amplify small changes in the field to produce large changes in neural activity.13 On the other hand, earlier tests of Kohler's theory found that interference with electrical gradients over the cortex had no effect on behavioral measures (see note 11 for reference to these studies).

In recent decades, thanks to the behavioral sciences and the psychotherapeutic disciplines, tools for testing the impact of various forms of religion on people's lives have begun to become available.

To illustrate the range of possibilities for this line of research, I will describe a gedanken experiment in which a behavioral assay of feelings is employed to test the hypothesis that atoms are sentient individuals.

When you present the facts about school breakfast, and its associated benefits — increased test scores, fewer behavioral problems, improved focus in the classroom — you give stakeholders the opportunity to understand the measurable results that come from feeding students a morning meal.

Animal testing indicates that pesticides can cause permanent changes in brain chemistry that may lead to behavioral disorders, learning disabilities, and even long - term damage to the brain and nervous system.

, 1968 Zick Rubin, «The Social Psychology of Romantic Love», 1969 Elliot Aronson, «Some Antecedents of Interpersonal Attraction», 1970 David C. Glass and Jerome E. Singer, «The Urban Condition: Its Stresses and Adaptations — Experimental Studies of Behavioral Consequences of Exposure to Aversive Events», 1971 Norman H. Anderson, «Information Integration Theory: A Brief Survey», 1972 Lenora Greenbaum, «Socio - Cultural Influences on Decision Making: An Illustrative Investigation of Possession - Trance in Sub-Saharan Africa», 1973 William E. McAuliffe and Robert A. Gordon, «A Test of Lindesmith's Theory of Addiction: The Frequency of Euphoria Among Long - Term Addicts», 1974 R. B. Zajonc and Gregory B. Markus, «Intellectual Environment and Intelligence», 1975 Johnathan Kelley and Herbert S. Klein, «Revolution and the Rebirth of Inequality: The Bolivian National Revolution», 1977 Murray Melbin, «Night as Frontier», 1978 Ronald S. Wilson, «Synchronies in Mental Development: An Epigenetic Perspective», 1979 Bibb Latane, Stephen G. Harkins, and Kipling D. Williams, «Many Hands Make Light the Work: The Causes and Consequences of Social Loafing», 1980 Gary Wayne Strong, «Information, Pattern, and Behavior: The Cognitive Biases of Four Japanese Groups», 1981 Richard A. Shweder and Edmund J. Bourne, «Does the Concept of the Person Vary Cross Culturally?»

The behavioral tests used here modeled one dimension of the disease — an inability to experience pleasure from normal activities — but not others, such as stress and anxiety, and probably tap into different brain mechanisms in mice than in humans, he says.

Focusing on the neural pathway from the brain's prefrontal cortex to the amygdala, they combined optogenetics — a technique that uses light to control the activity of neurons in living tissue — with behavioral testing, a methodology that allows researchers to study functional connections between different regions of the brain.

«The results are novel, as this sensitive and comprehensive testing has revealed how prenatal and early postnatal immune activation may regulate core behavioral signs associated with ASD and certain other developmental disorders through changes in signal flow between different structural components of behavior - driving neural circuits,» said Bolshakov.

While the group that received the combined maternal and postnatal treatment showed the largest behavioral effects, electrophysiology tests easily distinguished the pathway effects in each of the four treatment groups.

In contrast, no dose of haloperidol tested (0.5 to 12 milligrams per kilogram) produced rigidity, loss of righting reflex, or behavioral excitation.

«We have now found a potential mechanism, and at this point in our research, we need to test human participants in a blinded, placebo controlled clinical study — the same technique we used to study the behavioral effects of acupuncture in rats,» says Eshkevari, a nurse anesthetist and licensed acupuncturist.

Both Shaken and Stirred In addition to these behavioral measures, the scientists also tested for changes in the bees» neurotransmitter levels after shakinIn addition to these behavioral measures, the scientists also tested for changes in the bees» neurotransmitter levels after shakinin the bees» neurotransmitter levels after shaking.

Behavioral wavelength discrimination tests (Δλ functions) in stomatopods revealed a surprisingly poor performance, ruling out color vision that makes use of the conventional color - opponent coding system (6 — 8).

The depression study aims to enroll 600 patients in a 12 - week study testing two psychoactive drugs and cognitive behavioral therapy.

To see if CGP3466B, like ketamine, has antidepressant effects in mammals, the researchers used two standard behavioral tests on mice.

The development and implementation of the DSM - H is detailed in a study published in Geriatric Nursing, in which researchers tested the ability of their program to improve the knowledge, confidence, and attitudes of the HHC team members in assessing and managing pain, depression, and other behavioral symptoms in people living with dementia.

In a study now being reviewed for publication, Bookstein and Streissguth looked at the results of behavioral tests and brain scans of 45 adult men, 30 of them afflicted with either fetal alcohol syndrome or fetal alcohol effects, the others not.

Also, behavioral tests of motor function in post-stroke animals in correlation with BSCB damage are needed.

Given that behavioral tests can take up to two months and mice usually live four to five months in the lab, the mandate's costs add up quickly.

To identify the brain regions involved in canceling a decision, the new study recruited 21 subjects for a modified «stop signal task,» a commonly used neuroscientific behavioral test that involves canceling a planned movement.

He has also been working with neonate pine snakes in a variety of behavioral experiments, including simple maze tests to track migration and dispersal responses to different snakes» scents.

Other behavioral tests examine sociability, giving the mice the choice to spend time either with other mice or with inanimate objects; risk - taking, in which the mice either venture out on to a high open ledge or hide in a dark enclosed space; and repetitive behavior, where the focus is on excessive grooming or jumping.

The differences may show up, for example, in more complicated behavioral assays and drug tests, which Silverman and Yang are exploring.

According to Yang and Silverman, a typical behavioral test aims for 20 mice per group in order to achieve sufficient statistical power.

The U.S. National Institute of Mental Health's Project Accept — a trial conducted by the HIV Prevention Trials Network to test a combination of social, behavioral and structural HIV - prevention interventions — demonstrated that a series of community efforts boosted the number of people tested for HIV and resulted in a 14 percent reduction in new HIV infections, compared with control communities.

A new report, published online October 24 in the Journal of the Academy of Nutrition and Dietetics, reviews 18 carefully controlled laboratory studies that tested human subjects» physiological and behavioral responses to sleep deprivation as they relate to metabolic health.

Their results show that the program is as good at spotting behavioral markers of autism as experts giving the test themselves, and better than non-expert medical clinicians and students in training.

To test this hypothesis, the research team is now planning to explore the longer term behavioral impact of sleep - sacks in a larger group of preterm newborns.

In young and healthy adults, for example, a high demanding cognitive test was required to uncover the subtle immediate behavioral effects that cocoa flavanols have on this group.

Analyzing data on more than 4,000 participants in the Children of the 90s study at the University of Bristol, researchers from Harvard and Columbia's Mailman School of Public Health found that children with behavioral problems at the age of 8, had higher levels of two proteins (C - reactive protein — CRP; and Interleukin 6 — IL - 6) in their blood when tested at the age of 10.

They do social science, health, philosophical, policy, or legal research on topics such as privacy, confidentiality, the psychological impact of genetic information, informed - consent issues in genomics research, commercialization of genetic products, genetically modified foods, behavioral genetics, gene testing, and gene therapy.

Once the mice became 4 months old, their learning and memory skills were tested in various cognitive / behavioral tasks.

In tests where ants were smelled or seen, jumping spiders built far more web nests while spitting spiders built substantially fewer, the researchers report this week in Behavioral Ecology and SociobiologIn tests where ants were smelled or seen, jumping spiders built far more web nests while spitting spiders built substantially fewer, the researchers report this week in Behavioral Ecology and Sociobiologin Behavioral Ecology and Sociobiology.

Researchers then gave the mice several behavioral tests for «depression» including the forced swim test, in which researchers measure how fast the mice give up swimming and decide to float.

They verified that blood concentration levels were comparable to effective levels in humans being treated for bipolar disorder or mania, and then administered the open field and other behavioral tests.

In the study, the researchers used behavioral tests, as well as neuroimaging, to investigate whether there is an influence of biological sex on facial recognition, according to Suzy Scherf, assistant professor of psychology and neuroscience.

«If scientists want to test drugs for dementia, Alzheimer's or autism, ideal models would react similarly to humans in regards to the reduction of symptoms, outbreak of side effects, such as enduring the same lesions as humans do, or exhibiting similar behavioral characteristics,» said Latham, who's with the College of Agriculture and Natural Resources and an MSU AgBioResearch scientist.

We combined a behavioral test for magnetic compass orientation in mole rats and immunocytochemical visualization of the transcription factor c - Fos as a marker of neuronal activity.

They assessed the effects using behavioral tests, including putting food in the middle of an open space and timing the animals» response.

Next the team gave the mice a battery of behavioral tests that required them to poke their nose at panels in their enclosure to indicate which of three panels was a different color than the other two.

At the time of admission for functional MRI scanning (5 years after the ictus), the patient was assumed to remain in a vegetative state, although extensive behavioral testing after the functional MRI revealed reproducible, but inconsistent, responses indicative of a minimally conscious state.

In the course of screening over 180 mutant mouse strains with a systematic battery of behavioral tests, Dr. Tsuyoshi Miyakawa and his colleagues found that mice with heterozygous knockout of the alpha - isoform of calcium / calmodulin - dependent protein kinase II (αCaMKII) exhibit behavioral deficits and other brain features consistent with bipolar disorder.