Sentences with phrase «in brain samples»

ApoE4 causes a dramatic reduction in SirT1, as seen in both neuron cells and in brain samples from people with AD.

The authors of the new study — a multicenter effort led by Kent State University anthropologists C. Owen Lovejoy and Mary Ann Raghanti and published January 22 in PNAS — began by measuring neurotransmitter levels in brain samples from humans, chimpanzees, gorillas, baboons and monkeys, all of whom had died of natural causes.

George decided to take a closer look at the VTA and worked closely with Paul Sawchenko, professor at the Salk Institute who was part of the group that originally discovered CRF, to use radioactive RNA markers to detect CRF in brain samples from rodents.

They injected the molecules into mice to create antibodies capable of recognizing the various suspect proteins, and then searched through the antibodies to find those that stuck only to the clumps in brain samples of FTD patients.

Further, investigation of these CpG associations revealed nearby genes whose RNA expression was altered in brain samples with Alzheimer's disease: ANK1, CDH23, DIP2A, RHBDF2, RPL13, RNF34, SERPINF1 and SERPINF2.

Ronald Kahn and his colleagues at Harvard Medical School in Boston compared gene expression in brain samples from mice with type 1 or type 2 diabetes against those of healthy mice.

By the time the mouse was 10 months old, it had also lost old plaques, as shown in these brain samples.

Not exact matches

After taking samples and conducting brain scans, the researchers found that 41 percent of mothers of babies with microcephaly tested positive for Zika infection in blood or cerebrospinal fluid samples, compared with none of those whose babies did not have microcephaly.

Maja Pantic, a professor of affective and behavioral computing at Imperial College in London, tells Sample she is worried about a one - way brain drain from schools to tech companies:

Days after the report was released, the NFL released an official statement acknowledging the findings, but also suggesting that they may not be representative of all of the league's players: «The report doesn't confirm that the condition is common in all football players; it reflects high occurrence in samples at the Boston brain bank that studies CTE,» they wrote.

Researchers looked at 133 babies using specialized, «baby - friendly» magnetic resonance imaging to analyze brain growth in a sample of children under the age of 4.

In 2007, researchers published the first randomized, controlled study of the effect of being raised in an orphanage; that study, and subsequent research on the same sample of Romanian orphans, found that compared with babies placed with a foster family, those who were sent to institutions had lower IQs, slower physical growth, problems with human attachment and differences in functioning in brain areas related to emotional developmenIn 2007, researchers published the first randomized, controlled study of the effect of being raised in an orphanage; that study, and subsequent research on the same sample of Romanian orphans, found that compared with babies placed with a foster family, those who were sent to institutions had lower IQs, slower physical growth, problems with human attachment and differences in functioning in brain areas related to emotional developmenin an orphanage; that study, and subsequent research on the same sample of Romanian orphans, found that compared with babies placed with a foster family, those who were sent to institutions had lower IQs, slower physical growth, problems with human attachment and differences in functioning in brain areas related to emotional developmenin functioning in brain areas related to emotional developmenin brain areas related to emotional development.

«For the first time, we have found that a sample of randomly assigned young adults showed less activation in certain frontal brain regions following a week of playing violent video games at home,» said one researcher.

More work has to be done on humans as many of the results showed up in mice samples, however in studying the human brains of women who had AD scientists found significantly less male fetal tissue in their brains as in the same of women who did not have AD.

The researchers detected this SMN long noncoding RNA, or lnc - RNA (pronounced «link RNA») for short, in human embryonic kidney cells, brain cell samples and neurons derived from the stem cells of healthy people and those with spinal muscular atrophy type I and II.

Endocast researchers need to study the range of brain surface characteristics in a larger sample of living chimps and other apes to make more accurate comparisons, Falk says.

A team led by geneticist Steven McCarroll of the Broad Institute, based in Cambridge, Mass., combed through genetic information from about 29,000 schizophrenia cases, 36,000 controls and 700 brain samples from deceased patients.

Examinations of NFL players» postmortem brains turned up chronic traumatic encephalopathy in 99 percent of samples in large dataset.

The search for more of these factors is complicated by the rarity of brain samples from suicide victims and the lack of an animal model — humans are unique in their wilful ability to end their lives.

It has not been validated on blood samples from people with vCJD, because these have not been made available, says Moser — but the test can detect highly diluted vCJD brain homogenates, which contain the prion, in blood.

This study was conducted in samples taken from rat brains, but sleep is thought to induce backward firing in human neurons, too.

Whereas analyses of the brain were once limited to autopsy samples at the time of a person's death, advances in an imaging technique known as positron emission tomography (PET) now enable researchers to detect amyloid and tau in the brains of living people.

Meanwhile, other researchers are studying serum to garner clues about links between traumatic brain injury (TBI) and DNA methylation among individuals who served in Iraq and Afghanistan, gleaning information from samples on 150 service members with mild to severe TBI, along with 50 control subjects.

They've looked for BMAA in similar brain samples, and haven't seen it.

The few studies that have incorporated other training modalities, such as physical fitness training or noninvasive brain stimulation, have been small in sample size, short in time or narrow in scope, he said.

For a study published with Kuhnlein in 2002, Fediuk compared the vitamin C content of 100 - gram (3.55 - ounce) samples of foods eaten by Inuit women living in the Canadian Arctic: Raw caribou liver supplied almost 24 milligrams, seal brain close to 15 milligrams, and raw kelp more than 28 milligrams.

HBI member V. Wee Yong, PhD and research associate Susobhan Sarkar, PhD, and their team including researchers from the Department of Clinical Neurosciences and the university's Southern Alberta Cancer Research Institute, looked at human brain tumor samples and discovered that specialized immune cells in brain tumor patients are compromised.

Alzheimer's mice with normal BACE1 levels experienced a steady increase in plaques, clearly seen in samples of their brains.

One of the limits of the study, he said, was that his team could only assess the presence of antibodies in a blood sample, not a brain fluid sample.

She wondered whether the sampling used in brain imaging studies might affect the results scientists were seeing.

The researchers tested samples of brain cells from people with MS and healthy control subjects and found evidence of the virus in the olfactory bulb in both groups.

Working with an international group of scientists from Cardiff University, Stanford University and Duke University in addition to screening post-mortem brain samples from the Stanley Medical Research Institute, the scientists are the first to identify a molecular genetic component of the blood brain barrier with the development of schizophrenia.

These samples were collected primarily by Gianluigi Zanusso, M.D., Ph.D., and colleagues at the University of Verona in Italy, who developed the technique of brushing the inside of the nose to collect olfactory neurons connected to the brain.

What's more, they added, the sample is heavily weighted to men who played football in college or professionally, exposing them to far more hits to their heads than those who played only on youth or high school teams: These younger players accounted for only 16 brains in the sample of 202.

The team looked for these cells in nonliving brain samples in two ways: molecular markers that tag dividing cells and young nerve cells, and telltale shapes of newborn cells.

Accumulation of insoluble U1 protein was seen in samples from patients with mild cognitive impairment (MCI), a precursor stage to Alzheimer's, but the U1 pathology was not seen in any other brain diseases that were examined.

In comparison to RNA from healthy brains, more of the RNA from Alzheimer's brain samples was unspliced.

The strength of the paper, he says, is that the large number of animals involved provide a good sample of the different ways in which chimp brains age.

Working in Morrison's Neurotrauma and Repair Laboratory at Columbia Engineering, the team developed a blast injury model using a shock tube and custom - designed sample receiver to simulate a primary blast event and applied it to an isolated, living model of the BBB that consisted of brain endothelial cells.

In addition, the researchers looked at brain samples of deceased patients with MS and found increased numbers of GM - CSF - producing cells in comparison to normal brain sampleIn addition, the researchers looked at brain samples of deceased patients with MS and found increased numbers of GM - CSF - producing cells in comparison to normal brain samplein comparison to normal brain samples.

The researchers also discovered that a receptor — known as GluR4 — that the NPTX2 protein usually targets in the brain is also found in the kidney cancer samples.

The study divides 177 blood and 27 post-mortem brain samples into several groups, establishing that careful analysis of RNA transcripts in blood samples has the ability to distinguish early clinical AD, Parkinson's disease (PD), and cognitively healthy patients.

Focusing on Serengeti National Park in Tanzania, Marion East of the Institute for Zoo and Wildlife Research in Berlin and her colleagues analyzed brain and saliva samples collected from resident carnivores.

So a team led by autoimmunity researcher and rheumatologist J. Lee Nelson of the Fred Hutchinson Cancer Research Center in Seattle, Washington, took samples from autopsied brains of 59 women who died between the ages of 32 and 101.

A small skin sample from a person with bipolar disorder can yield stem cells that can be coaxed to become neurons just like those in the brain.

Researchers most commonly study the effect of antidepressants using a technique known as microdialysis, in which they insert a probe into the brain to take tiny chemical samples from the tissue.

After analyzing brain tissue samples, the researchers identified an area of the gene where a single change reduced BDNF levels in the hypothalamus, a key area that controls eating and body weight.

They confirmed low levels of miR - 184 expression in human glioma tissue samples and cultured cell lines as well as an increase in the expression of SND1 compared to normal brain tissue.

For the first time, scientists can use skin samples from older patients to create brain cells without rolling back the youthfulness clock in the cells first.

In examining autopsy samples from MS patients, the researchers detected an abundance of amyloids in brain lesions and damaged neurons, the hallmarks of the diseasIn examining autopsy samples from MS patients, the researchers detected an abundance of amyloids in brain lesions and damaged neurons, the hallmarks of the diseasin brain lesions and damaged neurons, the hallmarks of the disease.