Sentences with phrase «in cardiac tissue»

Optical control of excitation waves in cardiac tissue.

In this study, the presence of tau protein in cardiac tissue is confirmed and the functional role in the cardiovascular system and the consequences of its loss were explored.

In tissues such as liver and skeletal muscle, FAO can provide over 75 % of cellular adenosine triphosphate, while in cardiac tissue it can be responsible for up to 90 %.

Olive consumption is followed with the release of glutathione in cardiac tissue and the downregulation of carcinogenic activity throughout the body.

It's so unusual in the heart that doctors often write up their findings for medical journals when the tumors are found in cardiac tissue.

This is due to the progressive loss of cardiac strength and irreversible degeneration and remodeling that occurs in cardiac tissues.

Not exact matches

Among these are evaluation of cardiac function in real time, mapping of water diffusion and temperature in tissue, mapping of organ blood pool and perfusion, functional imaging of the central nervous system, depiction of blood and cerebrospinal fluid flow dynamics, and movie imaging of the mobile fetus in utero.

Scientists in Korea have designed a crablike robot that is smaller than the thickness of a fingernail and powered by contractions of cardiac tissue.

To solve this problem, Smadar Cohen, a tissue engineer at Ben - Gurion University of the Negev in Beersheba, Israel, and colleagues seeded rat cardiac cells onto scaffolds which they transplanted into the omentums of eight rats.

The researchers believe this is the first 3D in vitro cardiac tissue with three cell types that can beat together as one entity rather than at different intervals.

Matters of the heart can be complicated, but York University scientists have found a way to create 3D heart tissue that beats in synchronized harmony, like a heart in love, that will lead to better understanding of cardiac health and improved treatments.

In addition, the substance used to stick cells together (ViaGlue), will provide researchers with tools to create and test 3D in vitro cardiac tissue in their own labs to study heart disease and issues with transplantatioIn addition, the substance used to stick cells together (ViaGlue), will provide researchers with tools to create and test 3D in vitro cardiac tissue in their own labs to study heart disease and issues with transplantatioin vitro cardiac tissue in their own labs to study heart disease and issues with transplantatioin their own labs to study heart disease and issues with transplantation.

«For 2D or 3D cardiac tissue to be functional it needs the same high cellular density and the cells must be in contact to facilitate synchronized beating.»

In this research, Yousaf and his team made a scaffold free beating tissue out of three cell types found in the heart — contractile cardiac muscle cells, connective tissue cells and vascular cellIn this research, Yousaf and his team made a scaffold free beating tissue out of three cell types found in the heart — contractile cardiac muscle cells, connective tissue cells and vascular cellin the heart — contractile cardiac muscle cells, connective tissue cells and vascular cells.

The researchers transplanted the cardiac fibroblasts isolated from the region of calcification under the skin of healthy mice and observed soft - tissue calcification similar to that seen in the donor mice.

In a study published online in Circulation Research late last year, Chaudhry and colleagues found that fetal cells in mice migrated to the mother's heart, differentiated into functioning cardiac cells, and accelerated repair to damaged heart tissuIn a study published online in Circulation Research late last year, Chaudhry and colleagues found that fetal cells in mice migrated to the mother's heart, differentiated into functioning cardiac cells, and accelerated repair to damaged heart tissuin Circulation Research late last year, Chaudhry and colleagues found that fetal cells in mice migrated to the mother's heart, differentiated into functioning cardiac cells, and accelerated repair to damaged heart tissuin mice migrated to the mother's heart, differentiated into functioning cardiac cells, and accelerated repair to damaged heart tissue.

Investigators at the Cedars - Sinai Heart Institute — whose previous research showed that cardiac stem cell therapy reduces scarring and regenerates healthy tissue after a heart attack in humans — have identified components of those stem cells responsible for the beneficial effects.

A previous study from the MGH team found that injecting B cells into cardiac tissue damaged by a heart attack improved structural and functional recovery in an animal model.

Jana Petzold of the Erlangen team headed by Prof. Engel and Tamara Aigner from Prof. Scheibel's Bayreuth working group collaborated in investigating the suitability of the silk protein eADF4 (κ16) produced in the laboratory for the production of cardiac tissue.

In addition to cardiac cells, Petzold and Aigner attempted to apply other cells, such as connective tissue cells and blood vessel cells, to the film, and were successful each time.

Because they are interested in human heart failure, Lavine and his colleagues developed a method to progressively damage mouse cardiac tissue in a way that mimicked heart failure.

Heart valves are thin flaps of tissue in the heart, which ensure unidirectional flow of blood between the four chambers during the cardiac cycle.

12 guide RNAs developed to find mutation «hotspots» along the dystrophin gene helped rescue cardiac function to near - normal levels in human heart muscle tissue.

«The transmitted light exhibits pulses at the heart rate, due to cardiac - induced blood volume changes in the finger tissue.

In experiments to be published Tuesday, July 14, in the journal Nature Communications, the researchers used biochemical and biophysical cues to prompt stem cells to differentiate and self - organize into micron - scale cardiac tissue, including microchamberIn experiments to be published Tuesday, July 14, in the journal Nature Communications, the researchers used biochemical and biophysical cues to prompt stem cells to differentiate and self - organize into micron - scale cardiac tissue, including microchamberin the journal Nature Communications, the researchers used biochemical and biophysical cues to prompt stem cells to differentiate and self - organize into micron - scale cardiac tissue, including microchambers.

With the progression of heart regeneration, these cells were permanently installed in the muscle tissue and made their contribution to the restoration of cardiac function.

Researchers at the University of California, Berkeley, in collaboration with scientists at the Gladstone Institutes, have developed a template for growing beating cardiac tissue from stem cells, creating a system that could serve as a model for early heart development and a drug - screening tool to make pregnancies safer.

These cells can be used in a variety of tissue types, including bone, cartilage, fat, skeletal muscle, smooth muscle and cardiac muscle.

Researchers from the Gladstone Institutes, in collaboration with scientists at UC Berkeley, have developed a template for growing beating cardiac tissue from stem cells, creating a system that could serve as a model for early heart development and a drug - screening tool to make pregnancies safer.

Senior author of the paper Conor Walsh echoed Roche's sentiments, saying the sleeve «represents an exciting proof of concept result... demonstrating that it can safely interact with soft tissue and lead to improvements in cardiac function.»

GCSF and hypoxia inducible factor - 1α (HIF - 1α) have been shown to up - regulate SDF - 1α in the infarcted area in a rabbit ischemia model and promote the migration of CXCR4 expressing cells towards cardiac tissues [47 - 49].

To assess whether CAMKK1 can improve cardiac tissue repair, the group overexpressed CAMKK1 in MSCs and injected the modified MSCs or their conditioned medium (CM) into infarcted cardiac tissue at the time of AMI.

The Division of Pulmonary Medicine deals with the breath of life in all its aspects: control of breathing; sleep disorders; obstruction to airflow in the common diseases of upper and lower airways such as croup, bronchiolitis, asthma, cystic fibrosis, and bronchopulmonary dysplasia; restriction to lung function from disorders affecting the chest wall, the musculature, the nervous system, or lung tissue itself; congenital anomalies; accidents such as inhalation of foreign bodies, hydrocarbons, or toxic gases; secondary effects of non-pulmonary system disorders such as gastrointestinal reflux, myopathy, or cardiac dysfunction; disease of the upper respiratory tract including rhinitis and sinusitis; and so on.

Because of their unique regenerative potential, MSCs exhibit potential for use in tissue regeneration and repair for conditions such as cardiac anomalies or injury, bone disorders and metabolic diseases.

Cardiac repair in guinea pigs with human engineered heart tissue from induced pluripotent stem cells.

In addition to growing new skin for burn victims, cells from hair follicles could potentially be used to engineer vascular grafts and possibly regenerate cardiac tissues for patients with heart problems.

4/22/2008 Scientists Identify Novel Way to Prevent Cardiac Fibrosis In a study that points to a new strategy for preventing or possibly reversing fibrosis — the scarring that can lead to organ and tissue damage — researchers at the University of California, San Diego School of Medicine have determined that a molecul... More...

5/15/2008 New Role Found for a Cardiac Progenitor Population In a discovery that could one day lead to an understanding of how to regenerate damaged heart tissue, researchers at the University of California, San Diego have found that parent cells involved in embryonic development of the epicardium — the cell l.In a discovery that could one day lead to an understanding of how to regenerate damaged heart tissue, researchers at the University of California, San Diego have found that parent cells involved in embryonic development of the epicardium — the cell l.in embryonic development of the epicardium — the cell l...

As the investigators note, the rapid age - related arterial stiffening and cardiac arrhythmias that appear to be at cause for the majority of deaths in BubR1H / H mice were not attenuated by ablating p16Ink4a - expressing senescent cells — but these tissues had little burden of such cells, so this finding reinforces the conclusion that the multiple aging phenotypes arrested in these mice when senescent cells were ablated is attributable specifically to the removal of their baleful influence on local tissues.

Thus, these animals exhibit premature cardiac arrhythmias and stiffening of the arterial wall, and cardiac failure appears to be the main cause of death; yet these tissues are not burdened with an abnormally - high burden of p16Ink4a - senescent cells, and accordingly, ablation p16Ink4a - positive senescent cells in these animals had little tissue - specific or survivorship phenotypic impact.

The zebrafish heart robustly regenerates missing or damaged cardiac tissue following a partial ventricular resection procedure in as little as 30 - 60 days.

Unfortunately, in more four million people each year, these delicate tissues malfunction due to birth defects, age - related deteriorations, and infections causing cardiac valve disease.

In experiments published Tuesday, July 14 in the journal Nature Communications, the researchers used biochemical and biophysical cues to prompt stem cells to differentiate and self - organize into micron - scale cardiac tissue, including microchamberIn experiments published Tuesday, July 14 in the journal Nature Communications, the researchers used biochemical and biophysical cues to prompt stem cells to differentiate and self - organize into micron - scale cardiac tissue, including microchamberin the journal Nature Communications, the researchers used biochemical and biophysical cues to prompt stem cells to differentiate and self - organize into micron - scale cardiac tissue, including microchambers.

Cardiac cell therapy can be effective in improving your heart's function and reducing damage to heart tissue.

The Disease Biophysics Group has three open postdoctoral positions to be filled: 1) One position in skeletal muscle tissue engineering, 2) One position in cardiac muscle tissue engineering, and 3) One position in nanofibers and materials science (no biology background required).

SAN FRANCISCO, CA — Researchers at the University of California, Berkeley, in collaboration with scientists at the Gladstone Institutes, have developed a template for growing beating cardiac tissue from stem cells, creating a system that could serve as a model for early heart development and a drug - screening tool to make pregnancies safer.

In addition, HER2 is expressed in many normal tissues, giving systemic HER2 - targeted antibody therapy the potential to cause toxicity in a subset of patients, including cardiac myopathy, congestive heart failure, and pulmonary toxicity [14], [15In addition, HER2 is expressed in many normal tissues, giving systemic HER2 - targeted antibody therapy the potential to cause toxicity in a subset of patients, including cardiac myopathy, congestive heart failure, and pulmonary toxicity [14], [15in many normal tissues, giving systemic HER2 - targeted antibody therapy the potential to cause toxicity in a subset of patients, including cardiac myopathy, congestive heart failure, and pulmonary toxicity [14], [15in a subset of patients, including cardiac myopathy, congestive heart failure, and pulmonary toxicity [14], [15].

In fact, mammals have a limited repertoire of tissues they can regenerate, and some essential ones, such as nerves and cardiac muscle, are not on that list.

While novel treatment opportunities for heart disease, like microRNA therapeutics, are often effective, systemic delivery induces a low cardiac exposure and can lead to undesirable effects in other tissues.

At an April conference, Wagner claimed that a patch of this biomaterial infused with smooth muscle cells promotes healing and reduced formation of scar tissue in the hearts of rats recovering from cardiac arrest.