Sentences with phrase «in cell culture studies»

In a recent study, it was concluded that DIM rather than I3C was the active agent in cell culture studies destroying cancer.

In cell culture studies we published that ketone bodies (KB) inhibited growth of 7 different cancers from 20 - 50 %, leaving normal cells unaffected.

Using a mouse model for this disease, which in humans involves the destruction of white matter in the brain, a research team led by Albee Messing, director of the UW — Madison Waisman Center, found that a protein behind the symptoms of the disease, called GFAP, is broken down more rapidly in the body than researchers previously found in cell culture studies.

In cell culture studies, GS - 5734 was active against a broad spectrum of viral pathogens.

Not exact matches

Even an individual cell in our bodies is a responsive entity whose behavior can be studied in tissue culture.

In 2010, researchers from the University of Michigan Comprehensive Cancer Center published a study in the journal Clinical Cancer Research showing that sulforaphane had the ability to kill breast cancer stem cells in mice and in lab cultures, and it also prevented the growth of new tumor cellIn 2010, researchers from the University of Michigan Comprehensive Cancer Center published a study in the journal Clinical Cancer Research showing that sulforaphane had the ability to kill breast cancer stem cells in mice and in lab cultures, and it also prevented the growth of new tumor cellin the journal Clinical Cancer Research showing that sulforaphane had the ability to kill breast cancer stem cells in mice and in lab cultures, and it also prevented the growth of new tumor cellin mice and in lab cultures, and it also prevented the growth of new tumor cellin lab cultures, and it also prevented the growth of new tumor cells.

The study, «Polarity of varicosity initiation in central neuron mechanosensation,» which will be published June 12 in The Journal of Cell Biology, observes the swelling process in live cultured neurons and could lead to new ways of limiting the symptoms associated with concussive brain injuries.

This allowed them to track changes in calcium ion concentrations in the cells around wounds in living tissue (as opposed to the cell cultures used in many previous wound response studies) and to do so with an unprecedented, millisecond precision.

The research group studied the role of oxidative stress (see «The Two Faces of Oxygen») in cell senescence, and at Packer's request, Smith began teaching Pereira - Smith cell culture techniques.

Protein expression in these glioblastoma cells more closely mimicked that in real cancer cells than in 2D cultures of cells, indicating that this method could be used to study cancer (Nature Nanotechnology, DOI: 10.1038 / nnano.2010.23).

Now researchers at the University of Plymouth, working in partnership with pharmaceutical company AstraZeneca, have for the first time successfully cultured and maintained cells from the guts of rainbow trout, a recommended fish species for toxicological studies.

By studying the same process in cultured cells, the scientists found that the light stimulated a molecular chain reaction that activated a normally dormant protein called TGF - beta 1.

The study, in cell cultures and mice, tested a new approach of targeting stromal cells and cancer cells simultaneously.

In a new cell culture study, Sen found that sucralose appears to promote oxygen radical accumulation — a highly reactive particles that can cause disease and inflammation inside cells.

The study team removed fibroblasts (skin cells) from DBA patients, and in cell cultures, using proteins called transcription factors, reprogrammed the cells into iPSCs.

In addition, cell culture studies lasted two days in Gentzsch's study, whereas the clinical studies lasted for monthIn addition, cell culture studies lasted two days in Gentzsch's study, whereas the clinical studies lasted for monthin Gentzsch's study, whereas the clinical studies lasted for months.

Glutamine addiction has often been studied in cell culture systems that are genetically altered to overproduce c - MYC, a central regulator of growth and proliferation in all cells that is frequently de-regulated in cancers.

In studies with human fibroblasts that make up connective tissue, Boger's team tested whether NOD1 activity could affect CMV replication in cultures of cells grown in the laIn studies with human fibroblasts that make up connective tissue, Boger's team tested whether NOD1 activity could affect CMV replication in cultures of cells grown in the lain cultures of cells grown in the lain the lab.

Previous studies in cell culture have indicated that cell - to - cell infection may help HIV to resist antibodies and potent therapies.

«As a biologist, I needed simple yet tunable cell - culture gels that would give me a defined system to study metabolites in the laboratory.

The new research, which studied the immortalization process using genome - engineered cells in culture and also tracked skin cells as they progressed from a mole into a malignant melanoma, suggests that telomerase plays a more complex role in cancer.

In the study, the researchers show that after two to four weeks of 3 - D culture, the resulting muscle cells form muscle fibers that contract and react to external stimuli such as electrical pulses and biochemical signals mimicking neuronal inputs just like native muscle tissue.

These early studies were in laboratory - cultured cells.

«The fact that glutamine addiction has mainly been investigated in cell culture systems may have overestimated the lethality of glutamine deprivation,» said Martin Eilers, University of Würzburg, who led the study together with Kempa.

It seems we can now isolate the cells and study them in a pure culture, which is something that wasn't possible before.»

In a previous related study published in the Journal of Materials Science: Materials in Medicine, the same team of NTU scientists found that fish scale - derived collagen would induce human umbilical vein endothelial cells to express 2.5 times more of a specific type of collagen responsible for blood vessel formation, as compared to endothelial cells cultured on bovine collageIn a previous related study published in the Journal of Materials Science: Materials in Medicine, the same team of NTU scientists found that fish scale - derived collagen would induce human umbilical vein endothelial cells to express 2.5 times more of a specific type of collagen responsible for blood vessel formation, as compared to endothelial cells cultured on bovine collagein the Journal of Materials Science: Materials in Medicine, the same team of NTU scientists found that fish scale - derived collagen would induce human umbilical vein endothelial cells to express 2.5 times more of a specific type of collagen responsible for blood vessel formation, as compared to endothelial cells cultured on bovine collagein Medicine, the same team of NTU scientists found that fish scale - derived collagen would induce human umbilical vein endothelial cells to express 2.5 times more of a specific type of collagen responsible for blood vessel formation, as compared to endothelial cells cultured on bovine collagen.

In this study, Nicchitta and his colleagues treated tissue culture cells with a stress - inducing agent called thapsigargin.

In animal and cell culture studies, the drug inhibited growth both in estrogen - dependent breast cancer cells and in cells that had developed resistance to the anti-estrogen tamoxifen and / or to the aromatase inhibitors, two of the most widely used types of drugs to prevent and treat estrogen - dependent breast canceIn animal and cell culture studies, the drug inhibited growth both in estrogen - dependent breast cancer cells and in cells that had developed resistance to the anti-estrogen tamoxifen and / or to the aromatase inhibitors, two of the most widely used types of drugs to prevent and treat estrogen - dependent breast cancein estrogen - dependent breast cancer cells and in cells that had developed resistance to the anti-estrogen tamoxifen and / or to the aromatase inhibitors, two of the most widely used types of drugs to prevent and treat estrogen - dependent breast cancein cells that had developed resistance to the anti-estrogen tamoxifen and / or to the aromatase inhibitors, two of the most widely used types of drugs to prevent and treat estrogen - dependent breast cancer.

Studies of IBD are typically performed using cell culture experiments or animal models, which don't mimic the precise conditions that occur in the gut of human patients.

The Mount Sinai study found that harmine drove the sustained division and multiplication of adult human beta cells in culture, a feat that had eluded the field for years.

Their study, which appears as a letter in the Sept. 8 edition of Nature Medicine, expands on work published in April showing that a combination of ribavirin and interferon - alpha 2b stops MERS - CoV from replicating in cell culture.

protected animals»); studies on in vitro systems (whole perfused organs, tissue slices, cell and tissue cultures, and subcellular fractions); and human studies (including estimations of occupational and environmental exposure, postmarketing surveillance, epidemiology, and the ethical and strictly controlled use of human volunteers).

Six years ago, Dr. Monje started to create and share cell cultures of patients» DIPG cells that could be studied in labs.

In the study published in Nucleic Acids Research, the researchers were able to induce and inhibit the expression of genes in mammalian cell cultures and were able to regulate intracellular protein levels using light signalIn the study published in Nucleic Acids Research, the researchers were able to induce and inhibit the expression of genes in mammalian cell cultures and were able to regulate intracellular protein levels using light signalin Nucleic Acids Research, the researchers were able to induce and inhibit the expression of genes in mammalian cell cultures and were able to regulate intracellular protein levels using light signalin mammalian cell cultures and were able to regulate intracellular protein levels using light signals.

Next, the team used other mouse models in which part of the lung was removed and single cell culture to study the plasticity of cell types during lung regrowth.

In this study, she and her colleagues used cell cultures collected from 16 patients in the United States and Europe to search for drugs that could kill or stop the growth of DIPG cellIn this study, she and her colleagues used cell cultures collected from 16 patients in the United States and Europe to search for drugs that could kill or stop the growth of DIPG cellin the United States and Europe to search for drugs that could kill or stop the growth of DIPG cells.

In another study published this week the group investigated influenza pH1N1 virus - host cell interaction in detail and found that certain host function could be temporally inhibited with small molecule MK2206 to block influenza infection in cell culturIn another study published this week the group investigated influenza pH1N1 virus - host cell interaction in detail and found that certain host function could be temporally inhibited with small molecule MK2206 to block influenza infection in cell culturin detail and found that certain host function could be temporally inhibited with small molecule MK2206 to block influenza infection in cell culturin cell culture.

In the current study, Lasmézas and her team looked at cell cultures of neurons that were induced to accumulate fibrils made of misfolded α - synuclein, mimicking Lewy bodies in patients with Parkinson'In the current study, Lasmézas and her team looked at cell cultures of neurons that were induced to accumulate fibrils made of misfolded α - synuclein, mimicking Lewy bodies in patients with Parkinson'in patients with Parkinson's.

They showed in previous studies with cell cultures that when adding RK - 33 to malignant lung and other cancerous cells that highly express DDX3, proliferation slowed or halted, and the cells» ability to form colonies was impaired.

According to McCague, «the rarity of human prostate cancer cell cultures makes studying tamandron's potential difficult in the test tube.»

This is the first time these pathways have been studied in live mosquitoes with dengue virus, although similar studies have been conducted under controlled conditions using cells cultured in the lab.

In a paper published in the journal Proceedings of the National Academy of Sciences, Sangeeta Bhatia of MIT and Charles Rice of Rockefeller University describe using microfabricated cell cultures to sustain hepatitis B virus in human liver cells, allowing them to study immune responses and drug treatmentIn a paper published in the journal Proceedings of the National Academy of Sciences, Sangeeta Bhatia of MIT and Charles Rice of Rockefeller University describe using microfabricated cell cultures to sustain hepatitis B virus in human liver cells, allowing them to study immune responses and drug treatmentin the journal Proceedings of the National Academy of Sciences, Sangeeta Bhatia of MIT and Charles Rice of Rockefeller University describe using microfabricated cell cultures to sustain hepatitis B virus in human liver cells, allowing them to study immune responses and drug treatmentin human liver cells, allowing them to study immune responses and drug treatments.

The research highlights the importance of studying the effects of drugs not only on the tumor cells in a culture plate, but also on the interaction of the tumor cells with their own microenvironment.

An experimental drug that targets abnormally high levels of a protein linked to cancer growth appears to significantly reduce the proliferation of prostate cancer cells in laboratory cell cultures and animals, while also making these cells considerably more vulnerable to radiation, according to results of a study led by Johns Hopkins scientists.

In the new study, the researchers cultured mouse skin - cancer colonies on various 2 - D and 3 - D environments of different shapes and patterns to see if the tumor shape contributes to activation of cancer stem cells, and to see where in the tumor the stem cells appeareIn the new study, the researchers cultured mouse skin - cancer colonies on various 2 - D and 3 - D environments of different shapes and patterns to see if the tumor shape contributes to activation of cancer stem cells, and to see where in the tumor the stem cells appearein the tumor the stem cells appeared.

Studies by Bausch and others have also detected live Ebola virus in sexual fluids that can successfully grow in cell culture, suggesting it could also lead to infections in other individuals.

Now that they have shown how this defense mechanism works in cultured cells, they hope to study the importance of LINE - 1 jumping and the defenses against it in specific diseases.

Sood and his team first studied the effects of stress hormones on human ovarian cancer cell anoikis in culture.

They then conducted biochemical analyses to identify neuroligin - 3, confirm that the protein could stimulate tumor growth in cultured samples of several kinds of human high - grade gliomas and study which signals the protein uses within glioma cells to promote their growth.

The investigators studied application of various doses of a common PBDE flame retardant on human adrenal cells in culture dishes and compared the effects with those of only the vehicle, the inactive substance used to deliver the chemical.