Not exact matches
This crosslinking mechanism has been used to produce tissue sealants from polymers that are commonly used
in tissue engineering studies — fibrinogen and gelatin (Elvin et al. 2011; Elvin et al. 2010), but so far, there have been relatively few studies using Ruthenium - mediated crosslinking for
cell encapsulation.
In an effort to improve this, we employed an alginate encapsulation strategy for human mesenchymal stem cells (hMSCs) and attached them to the heart with a biocompatible PEG hydrogel patch in a rat MI mode
In an effort to improve this, we employed an alginate
encapsulation strategy for human mesenchymal stem
cells (hMSCs) and attached them to the heart with a biocompatible PEG hydrogel patch
in a rat MI mode
in a rat MI model.
Exploitation of alternative
cell sources (xenogeneic primary islets, stem
cell derived beta
cells) for utilization
in our
encapsulation device (collaboration with Anthony Gavalas, CRTD)
* Contains practical, hands - on information for tissue engineers and students * Provides comprehensive protocols covering numerous topics, including polymer synthesis,
cell culture,
encapsulation, bioreactors, therapeutics, and the creation of tissues and organs * Includes contributions by leaders
in the latest areas of research, such as stem
cells and fetal tissue engineering
The recent advances
in xenotransplantation and particularly
in the field of stem
cell - derived beta
cells have generated a renewed scientific interest
in encapsulation technology.
In terms of which approaches people are taking which might bear fruit clinically most quickly; could you compare the transplantation
encapsulation strategies with a stem
cell based immune response - centered approach?
The VC - 01 combination product is based on the production of pancreatic progenitor
cells (PEC - 01 ™
cells), which are implanted
in a durable and retrievable
encapsulation device, known as the Encaptra ® drug delivery system.
Its core expertise is
in efficient differentiation and
encapsulation of human stem
cells for therapeutic applications
in diabetes.
Our therapy is based on the
encapsulation and implantation of pancreatic beta
cell progenitors (Pro-Islet-1) derived from human stem
cells which secrete insulin
in patients.
We then evaluated whether the
encapsulation of hPSC - CDH5 +
cells in PA - RGDS could enhance long - term
cell survival and vascular regenerative effects
in a hind - limb ischemia model with laser Doppler perfusion imaging, bioluminescence imaging, real - time reverse transcription - polymerase chain reaction, and histological analysis.
ViaCyte's product candidates are based on the derivation of pancreatic progenitor
cells, which are then implanted
in a durable and retrievable
encapsulation device.
These
cells are implanted
in a durable and retrievable
encapsulation device called the Encaptra ® drug delivery system.
Thanks to a breakthrough
in solar
cell structure and
encapsulation techniques by the Frauenhofer Institute, solar
cells integrated into complex surfaces are expected to be on the shelves by the end of this year.