We are also investigating endocytosis of the cell surface receptor, Notch, a protein involved
in cell fate specification (6).
Kelly earned her Ph.D. in Cell and Molecular Biology from the University of Pennsylvania studying the role of the EGF - Ras - ERK signaling pathway
in cell fate specification.
Not exact matches
We focus on how changes
in chromatin structure orchestrate the developmental transitions from fertilization to genome activation to
cell fate specification.
Among them, there are genetic instability (mainly aneuploidy, a defect
in chromosome number), defects
in the symmetry of
cell division (important for
cell fate specification and tissue architecture) and impaired ciliogenesis.