Sentences with phrase «in cells expressing»

Although the yeast cells in these micrographs are expressing specific prion - like proteins (green, expressed protein label along top of micrographs), neither yeast containing prion - like proteins or the control exhibit the large protein masses expected in cells expressing prions.

Luciferase expression was markedly lower in cells expressing Bach1, indicating effective repression of HMOX1 E2 - dependent transcription by Bach1 (Figure 6B).

Vesicles in the cells expressing BNPI loaded two to four times more glutamate than those from the unaffected cells.

Oil droplets, outer, and inner segments were observed in cells expressing photoreceptor specific markers (Figure 7B and 7C).

Not exact matches

While nanog is weakly expressed in the late morula, it is clear that nanog expression is rapidly restricted to the cells of the inner - cell mass.

Conversely, if God is seen primarily as the expressed psychicalization in process of a multiplicity of event - cells, how can there be anything more than just that: psychicalized event - cells?

If the reality at work is the inner creativity of God expressing himself as, among other things, the «low - level universals» of a multiplicity of «I's» or as expressing himself in the supposed subjectivity of psychicalized cells, how exactly does my present self - awareness derive from this?

One clear positive element in the stem - cell debate for me was hearing the top researchers in biomedical science reinforce The Catechism of the Catholic Church (CCC 343: «Man is the summit of the Creator's work, as the inspired account expresses by clearly distinguishing the creation of man from that of other creatures»).

Likewise, we should not suppose that the liver cells aim to store glycogen in order to benefit the muscles; carbohydrate metabolism in the liver merely expresses the complex ways in which the many sub-societies in those cells are «pleased» to enjoy themselves in their immediate environments.

When a critical load cell broke down at an ice cream producer's plant, production was restored in 12 hours thanks to a hand - carry express order.

The change in load cell output occurring with time, while under load, and with all environmental conditions and other variables remaining constant; usually measured with Rated Load applied and expressed as a percent of Rated Output over a specific period of time.

In the new study, the scientists expressed surprise that the early abnormal growth of brain cells they observed in the fish embryo specifically affected male hormones, potentially indicating why more boys than girls are diagnosed with certain neurodevelopmental disorders such as autisIn the new study, the scientists expressed surprise that the early abnormal growth of brain cells they observed in the fish embryo specifically affected male hormones, potentially indicating why more boys than girls are diagnosed with certain neurodevelopmental disorders such as autisin the fish embryo specifically affected male hormones, potentially indicating why more boys than girls are diagnosed with certain neurodevelopmental disorders such as autism.

This approach revealed a highly sensitive portrait of the genes being expressed in human milk - making cells.

Hoylman supports the campaign to remake Fifth and Sixth Avenues into complete streets, backs the MoveNY fair - tolling plan, and has expressed interest in introducing legislation that would make it easier for law enforcement to secure cell phone records after vehicular crashes.

Mishra's team focused on a neurotransmitter called brain natriuretic peptide (BNP), which is expressed in a small number of sensory nerve cells or neurons.

Because the human cells had been genetically engineered to express green fluorescent protein, the tiny blobs showed up in brilliant lime through the transparent window that the scientists glued into the mice's skull.

The scientists discovered that the two sides of the cell differ in the composition of messenger RNA, or mRNA: About 30 percent of the genes expressed in the intestines produced mRNAs that appeared either on one side of the cell or on the other.

So, the researchers — headed by Professor of Physics and Biological Sciences Shane Hutson and Associate Professor of Cell and Developmental Biology Andrea Page - McCaw — targeted cells on the back of fruit fly pupae that expressed a protein that fluoresces in the presence of calcium ions.

Immunophenotyping — a laboratory procedure used to study the proteins expressed by cells — is very commonly used in basic science research as well as in laboratory diagnostic testing.

The compound (right panel) has a scorpion - like shape with two arms grabbing EphA2 - expressing cancer cells, and a tail (brown) constituted by a cytotoxic chemotherapeutic agent (paclitaxel used in this work).

«In addition, changes in how the genes are expressed (turned on or off) could be used in the future to predict how and when the cancer cells will spread to other parts of the body and how fast they will grow.&raquIn addition, changes in how the genes are expressed (turned on or off) could be used in the future to predict how and when the cancer cells will spread to other parts of the body and how fast they will grow.&raquin how the genes are expressed (turned on or off) could be used in the future to predict how and when the cancer cells will spread to other parts of the body and how fast they will grow.&raquin the future to predict how and when the cancer cells will spread to other parts of the body and how fast they will grow.»

«We think that these genes, which are normally only expressed in the placenta to facilitate invasion, are becoming reactivated in cancer cells and supporting invasion in this context too,» she says.

Multi-nucleus cells expressing genes needed to form skeletal muscle can be seen in flower - like clumps forming as cells fuse together.

The scientists also generated a panel of (reconstructed) ancestral and existing TRIM5 genes (19 total), expressed them in cultured cell lines, and exposed the cells to 16 different retroviruses (lentiviruses and others) to see which TRIM5 versions conferred resistance to which viruses.

«This is both time - consuming and often difficult, because the genetically modified receptors have to be expressed in living cells.

«The fact that a [cell] culture expresses most genes present in the brain says nothing about its appropriateness as a disease model,» says Knoblich.

A team led by Byeong - Chun Lee of Seoul National University in South Korea created the dogs by cloning fibroblast cells that express a red fluorescent gene produced by sea anemones.

The trimer - expressing cells even died more quickly than cells expressing mutant forms of SOD1 that are found in severe hereditary ALS cases.

Microglia are the only cells in the brain that express the receptor CX3CR1.

They found significant differences in RNA molecules in the cumulus cells of older patients when compared to RNA expressed in cells of patients younger than 35.

They found — as they did in the 2016 study — that when these cells expressed SOD1 mutants that predominantly form trimers, the cells died much more quickly than control cells containing normal SOD1.

Yu said the impairment of sensory nerve regeneration in diabetic corneas is due to decreased ciliary neurotrophic factor, as evidenced by the fact that dendritic cells express ciliary neurotrophic factor (CNTF) in normal and healing corneas but decrease in diabetic corneas due to the reduced infiltration of dendritic cells.

Another is to change the number of expressed copies of a gene in each cell.

Since genes for the T - cell receptor beta chain were previously shown to be on mouse chromosome 6, all three of the Ig - like multigene families expressed and rearranged in T cells are located on different chromosomes, just as are the B - cell multigene families for the Ig heavy chain, and the Ig kappa and lambda light chains.

In the GD2 CAR - T treated animals, the residual cancer cells did not express GD2, suggesting that these remaining cells were not vulnerable to the immune therapy and might be able to cause the cancer to recur.

The findings by a team of Massachusetts General Hospital (MGH) investigators, which will be published in the April 24 issue of Cell and are receiving advance online release, support the importance of epigenetics — processes controlling whether or not genes are expressed — in cancer pathology and identify molecular circuits that may be targeted by new therapeutic approaches.

There are hundreds of RNA - binding proteins in the human genome that together regulate the processing, turnover and localization of the many thousands of RNA molecules expressed in cells.

Monitoring mRNA could tell scientists a great deal about which genes are being expressed in a cell, and tweaking the translation of mRNA would allow them to alter gene expression without having to modify the cell's DNA.

Interestingly, two additional Nature papers released simultaneously with the Regev and Kuchroo team's study revealed that ILC2 cells in the gut also express Nmur1, take on an inflammatory state when exposed to NMU, and live in close proximity to NMU - producing nerve cells.

CRH, in turn, triggered production of the cell surface protein FasL; trophoblasts expressing FasL then form a protective shield of sorts around the embryo by forcing any attacking immune cells to self - destruct.

«Opioids have both analgesic and rewarding effects and they have these effects through mu opioid receptors and these receptors are expressed in pain terminals in the spinal cord and in areas of the brain that regulate pain but are also expressed in areas that regulate reward and a sense of pleasure,» Boyle said, referring to cells found in a person's central nervous system that bind to naturally occurring opioid compounds and reduce pain and make people feel much better.

The researchers found that aggressive LUAD cells expressed a number of proteins that allow them to persist outside the lungs in small numbers.

In a series of experiments, the researchers first identified a set of 19 transcription factors that were expressed at significantly greater levels in cultured human glioblastoma stem cells capable of tumor propagation than in differentiated tumor cellIn a series of experiments, the researchers first identified a set of 19 transcription factors that were expressed at significantly greater levels in cultured human glioblastoma stem cells capable of tumor propagation than in differentiated tumor cellin cultured human glioblastoma stem cells capable of tumor propagation than in differentiated tumor cellin differentiated tumor cells.

Published in the February 27 issue of Cell, the study found that tumor cells that reach the brain — and successfully grow into new tumors — hug capillaries and express specific proteins that overcome the brain's natural defense against metastatic invasion.

This protein is expressed at relatively high levels in proliferating precursors and non-neuronal cells but down - regulated in developing neurons by a brain - enriched regulatory RNA called miR - 9.

Each cell expresses a different color, allowing researchers to trace connections in the fish's neural network.

Then they linked the drug sensitivity of the tumor cells to the profile of genes expressed in those cells.

«With Rudolph,» Farber says, «the coral DNA got inserted into a gene that is normally expressed in the nasal epithelial cells, the cells of his nose.

When tumor cells that no longer express CCR3 are implanted in the prostates of mice, tumor progression and dissemination are significantly reduced, especially in obese mice.

«We have been able to show that this protein is highly expressed in metastatic triple - negative breast cancer, and when we are depleting it from triple - negative breast cancer cells, we found that the cancer cells are not metastasizing,» Dr. Paul said.