Sentences with phrase «in cells in the laboratory»

He was scouring the scientific literature when he hit upon an article describing high - throughput screening, a new technique that used robots to test the therapeutic properties of thousands of chemical compounds a day in cells in laboratory dishes.

Carried out in cells in the laboratory, in mice and in samples from patients» tumours, the researchers showed this «safe haven» lets melanoma cells turn on a parallel set of cell signals that helps them survive.

«Instead of gene therapy being done in the patient, as is the case in cancer, it's being done in the cells in a laboratory before doctors use them for therapy so that they still have control of these cells,» Dr. Crystal explains.

Not exact matches

Future Meat Technologies is working to commercialize a manufacturing technology for fat and muscle cells that was first developed in the laboratories of the Hebrew University of Jerusalem.

Previously, Dr. Nikolic was an Assistant Professor in Medicine at Harvard Medical School where he led an advanced immunology laboratory for tolerance induction and stem - cell transplantation at Massachusetts General Hospital / Harvard Medical School.

In both cases, cells derived from an adult individual are maintained in the laboratory under conditions where the cells replicate (or «clone» themselvesIn both cases, cells derived from an adult individual are maintained in the laboratory under conditions where the cells replicate (or «clone» themselvesin the laboratory under conditions where the cells replicate (or «clone» themselves).

Even scientist tried to replicate to see if they can product a single - celled organism in a laboratory.

Extracts from this garlic even protected cells in a laboratory dish from certain types of damage.13 This isn't really surprising when you consider the nutritional changes that typically occur in plants when they sprout.

In the laboratory, steviol can be converted into a mutagenic compound — if cell DNA becomes mutagenic, cancer may ensue.

While some still object to cells being taken from animals and used by scientists to grow clean meat in laboratories — and some just don't like the idea of eating a «cultured» steak created by men and women in white coats — others see the lab - grown meat revolution as key to solving the environmental crisis linked to meat eating.

There were Cavs jerseys and Indians jerseys and more jerseys and hats and jackets and jerseys, all mixing together like different dyed cells in a laboratory experiment.

Researchers at the European Union Reference Laboratory for alternatives to animal testing developed five different tests that use human blood cells to detect contaminants in drugs that cause a potentially dangerous fever response.

By encapsulating the follicles in the alginate and providing the growing cells with precise mixtures of nutrients and hormones, researchers at the ONPRC and elsewhere have been able to mimic the ovary's natural structure in the laboratory.

Scientists at the Johns Hopkins Kimmel Cancer Center say they have preliminary evidence in laboratory - grown, human airway cells that a condensed form of cigarette smoke triggers so - called «epigenetic» changes in the cells consistent with the earliest steps toward lung cancer development.

In a companion paper in Analytical Biochemistry, the Singh laboratory and the Bernd Friebe laboratory at the Department of Plant Pathology, Kansas State University, describe a molecular tool to rapidly detect and analyze insertion of mitochondrial DNA into the genomes of cellIn a companion paper in Analytical Biochemistry, the Singh laboratory and the Bernd Friebe laboratory at the Department of Plant Pathology, Kansas State University, describe a molecular tool to rapidly detect and analyze insertion of mitochondrial DNA into the genomes of cellin Analytical Biochemistry, the Singh laboratory and the Bernd Friebe laboratory at the Department of Plant Pathology, Kansas State University, describe a molecular tool to rapidly detect and analyze insertion of mitochondrial DNA into the genomes of cells.

To create the effect of tobacco smoke on cells, Vaz, Baylin and their colleagues began their studies with human bronchial cells, which line the airways of the lungs, and grew them in a laboratory.

Nathaniel Hoyle of the MRC Laboratory of Molecular Biology in Cambridge, UK, and his colleagues have discovered that genes in a type of skin cell switch on and off during day - night cycles.

While other papers have examined these mutations using expensive and time - consuming experiments on live ferrets and laboratory cell cultures, Deem and Melia Bonomo used the pEpitope method to rapidly calculate how much the egg - passage mutations would decrease vaccine efficacy in humans.

But in 2013, a research scientist in El - Naggar's laboratory, Sahand Pirbadian, discovered that these projections, referred to as «nanowires,» were actually extensions of the cell membrane covered in cytochromes — proteins containing iron that facilitate electron transport.

In addition to managing the cell bank, the facility makes culture media and maintains a resale storeroom for laboratory products.

The German - born Frank, who was inducted as a AAAS fellow in 1997, is a professor of biochemistry, molecular biophysics and biological sciences at Columbia in New York City and the Scottish - born Henderson, who has been a AAAS member since 1996, has served as director of the MRC Laboratory of Molecular Biology research facility where hundreds of scientists work on neurobiology, cell biology and biotechnology.

Immunophenotyping — a laboratory procedure used to study the proteins expressed by cells — is very commonly used in basic science research as well as in laboratory diagnostic testing.

The long - term persistence of CD8αα + T cells where initial infection occurs may explain why patients have asymptomatic recurrences of genital herpes because these cells constantly recognize and eliminate the virus, according to Jia Zhu, Ph.D., corresponding author, research assistant professor in Laboratory Medicine at the University of Washington and an affiliate investigator in the Fred Hutch Vaccine and Infectious Disease Division.

First, the effects they saw have so far only been replicated in cells growing in a laboratory dish, using high concentrations of AA147.

Using these cells, the team modeled the patients» neurons and blood - brain barrier in a laboratory dish.

The researchers instructed 146 college students to sit in an austere laboratory for up to 15 minutes without cell phones, books or other distractions, entertaining themselves with only their thoughts.

As reported June 13 in Cell Reports, a topical drug penetrated and tanned laboratory samples of live human skin, absent the sun.

The researchers found between four and 28 viable cells per passport photo — size unit of area — similar to those in clean rooms at the NASA Jet Propulsion Laboratory in Pasadena, California, and the Kennedy Space Center in Florida where spacecraft are assembled.

Chan's laboratory uses genomic analyses to identify neoantigens — novel peptides found only in tumors that arise from mutations accumulated by cancerous cells.

We wanted to understand what types of differences are always there, what is causing them, and what they mean,» says Juan Carlos Izpisua Belmonte, a professor in Salk's Gene Expression Laboratory and co-senior author, with Kelly Frazer of the University of California, San Diego, on the new paper, which was published in Cell Stem Cell in April 2017.

According to the latest studies from the fly laboratory of California Institute of Technology (Caltech) biologist David Anderson, male Drosophilae, commonly known as fruit flies, fight more than their female counterparts because they have special cells in their brains that promote fighting.

Researchers from Duke University had previously used CRISPR to correct genetic mutations in cultured cells from Duchenne patients, and other labs had corrected genes in single - cell embryos in a laboratory environment.

They simulated pressures that were beyond the highest possible pressures attainable in the laboratory with instruments called diamond anvil cells.

They would add a liter of the tissue to two liters of seawater and shake the mixture 75 times — no more, no less — to make «the individual light - producing cells pop out of the tissue,» according to Bill Ward, a bioluminescence researcher at Rutgers University in New Jersey who was a post - doc in Cormier's laboratory.

«She was a real pioneer in defining the genetics of cellular immortality,» says cell biologist Judith Campisi of Lawrence Berkeley National Laboratory in Berkeley, California.

Beginning in the 1970s, physicians learned how to harvest skin stem cells from a patient with extensive burn wounds, grow them in the laboratory, then apply the lab - grown tissue to close and protect a patient's wounds.

In an amazing feat of tissue engineering, Anthony Atala and his research team at the Children's Hospital in Boston are creating new organs in the laboratory using patients» own cells and by employing the same technology used to clone Dolly the sheeIn an amazing feat of tissue engineering, Anthony Atala and his research team at the Children's Hospital in Boston are creating new organs in the laboratory using patients» own cells and by employing the same technology used to clone Dolly the sheein Boston are creating new organs in the laboratory using patients» own cells and by employing the same technology used to clone Dolly the sheein the laboratory using patients» own cells and by employing the same technology used to clone Dolly the sheep.

When these cultured cells were exposed to an air / liquid interface in the laboratory, they stratified, generating what the authors referred to as a multi-layered, «skin - like organoid.»

After deciphering this natural differentiation process, the investigators duplicated it in the laboratory dish by adding a sequence of proteins, called growth factors, to the fluid bathing the stem cells.

Three of these themes represent the key scientific steps in moving stem cells from the laboratory into the clinic — the bioengineering and biology of stem cells, and the clinical applications of that research.

A class of small molecules found in grapes, red wine, olive oil, and other foods extends the life of yeast cells by approximately 70 % and activates genes known to extend life span in laboratory animals.

When RCGD 423 was applied to joint cartilage cells in the laboratory, the cells proliferated more and died less, and when injected into the knees of rats with damaged cartilage, the animals could more effectively heal their injuries.

Dr. Bellodi's laboratory uncovered a new important function of pseudouridine, the most common type of RNA modification in human cells.

Grouping T cell receptors for a given epitope revealed underlying common features that characterized the bulk of the repertoire,» said first author Pradyot Dash, D.V.M., Ph.D., a staff scientist in Thomas» laboratory.

Research for the study was conducted by first co-authors Dr. Ranit Kedmi and Nuphar Veiga and colleagues at Prof. Peer's TAU Laboratory, in collaboration with Prof. Itai Benhar of TAU's School of Molecular Cell Biology and Biotechnology, Dr. Michael Harlev of TAU's Veterinary Service Center, Dr. Mark Belkhe of Integrated DNA Technologies (IDT) and Prof. Judy Lieberman of Boston Chidren's Hospital and Harvard Medical School.

Scores of laboratories at universities and in private industry are uncovering how to use these cells, which transform into neurons, astrocytes (the cells that regulate transmission of electrical impulses in the brain) and oligodendrocytes (which insulate nerve fibers with a fatty coating).

In laboratory experiments, the team successfully coaxed CBEs into becoming liver cells.

«The siRNA delivery targeted carriers constructed today hone in on specific cells and require chemical conjugation of the targeting agent,» says Prof. Dan Peer of the Laboratory of Precision Nanomedicine at TAU's School of Molecular Cell Biology and Biotechnology, who led the research.

Adding stem cells from human bone marrow to a broken diabetic bone enhances the repair process, increasing the strength of the newly formed bone, according to a laboratory - based study presented at the European Congress of Endocrinology in Dublin.

The researchers added human bone marrow stem cells from a non-diabetic donor to a bone fracture in laboratory pre-clinical studies.