Sentences with phrase «in cellular adhesion»

Huntingtin null neurons exhibit a significant reduction in transcripts encoding proteins destined for the extracellular space, many of which are components of the extracellular matrix or involved in cellular adhesion, receptor binding and hormone activity.

Not exact matches

The relationship between cellular adhesion and spread is a key factor in cancer metastasis.

A team of researchers led by Professor Lindsay Hinck at the University of California, Santa Cruz, examined the ROBO signaling pathway in breast epithelial cells and found that one family member, ROBO1, enhances cellular contractility and stimulates assembly of cell - matrix adhesions.

Knowing how cells exert force and sense mechanical feedback in their microenvironment is crucial to understanding how they activate a wide range of cellular functions, such as cell reproduction, differentiation and adhesion — basic physiological processes that underlie embryo development, tumor metastasis, wound healing and many other aspects of human health and disease.

This, in turn, enhanced cellular contractility and adhesion, allowing cells to retain their shape and position within stiff extracellular matrices.

Studies have established that CD47 is involved in a range of cellular processes, including apoptosis, proliferation, adhesion and migration.

Once the bacterial cell signaling protein cagA reaches the host cytosol, it is capable of altering subsequent generations of progenitor cells, leading to the development of cancer through changes in mitotic activity, apoptosis, cellular assembly, and signaling.26 Although it should be noted that while the presence of the cagA protein doubles the risk of gastric cancer, cagA - negative strands also increase the risk of distal gastric cancer.27 Additional H pylori virulence factors include babA2, which encodes bacterial adhesion with gastric epithelial cells, and vacuolating cytotoxin A, which is encoded by the gene vacA.28, 29 H pylori strains carrying some combination of the babA2, cagA, and vacA genes were associated with the highest risk of developing intestinal metaplasia.

The work has led him to explore the role of protein phosphorylation in a diverse array of cellular functions, including transformation, cell communication, cell adhesion, cell - cycle regulation, the control of gene expression, and protein degradation.

Vinculin aggregates were detected in the cellular protrusions, frequently colocalizing with collagen fibers, implying they correspond to adhesion structures in 3D.

Studies cover a breadth of topics ranging from single molecules (molecular motors, DNA - protein interactions, membrane proteins) to cellular functions (cell adhesion, cell division, cell motility, intracellular transport) and the collective behaviour of cells in tissues and organisms (wound healing, morphogenesis).

The vaccinated Purdue dogs also developed autoantibodies to laminin, which is involved in many cellular activities including the adhesion, spreading, differentiation, proliferation and movement of cells.