Sentences with phrase «in cellular assays»

The researchers crossed two broccoli lines and tested their progeny in terms of total phenolic content and their ability to neutralize oxygen radicals in cellular assays.

The researchers crossed two broccoli lines and tested their progeny in terms of total phenolic content and their ability to neutralize oxygen radicals in cellular assays.

As in cellular assays, the animal studies have shown that drug treatment leads to improvement in nuclear gem / Cajal body numbers in motor neurons.

Not exact matches

Mass spectrometry ‐ based cellular thermal shift assay (MS ‐ CeTSA) analysis of CDK4 / 6 inhibitor palbociclib targets in MCF7 human breast cancer cells identifies protein complexes including the 20S proteasome.

In addition, pre-coated plates for different cellular assays are available.

A Phase 1 study in malaria - naïve North American volunteers found that the AMA1 - based vaccine FMP2.1 / AS02A elicited potent humoral and cellular immune responses and that immune sera recognized sporozoites and merozoites by immunofluorescence assay and inhibited both parasite growth and AMA1 processing in homologous 3D7 parasites [16].

Live cell assays constructed with genetically encoded, fluorescent biosensors can provide significant advantages over endpoint assays measured in cell lysates because functional information about the timing and location of cellular responses can be monitored in cells that are relevant to disease.

We will specifically employ cellular bioassays including the monocyte monolayer assay and antibody - dependent cellular inhibition assay to determine the role of cellular effector mechanisms in anti-PfSEA-1 mediated immunity.

Topics such as the mechanisms of cell injury in normal and dystrophic muscle, compensatory muscle regeneration and hypertrophy, and the effects of various therapies or voluntary exercise on muscle repair, satellite cell activation, muscle growth, bone density and age - related atrophy are examined using a large variety of cellular, molecular and whole - animal in vivo assays of function.

Prior to joining Ricerca Biosciences, she developed in vitro cellular immunology assays as a postdoctoral research fellow at Children's Hospital and Regional Medical Center, Department of Immunology in Seattle, WA.

The combination of the high structural similarity between UNC0737 and UNC0638 and the > 300-fold loss of potency in UNC0737 compared to UNC0638 makes UNC0737 an appropriate negative control for use in cellular and functional assays.

For example, assaying the genomes of multiple cells during development reveals developmental lineage trees - the kinship lineage - whereas cellular transcriptomes inform us about the regulatory state of cells and their gradual restriction in potency - the Waddington lineage.

In collaboration with Pär Nordlund, Karolinska Institutet, researchers from Chemical Biology Consortium Sweden at SciLifeLab have published a study in Nature Communications where they demonstrate high throughput screening capability of a method called cellular thermal shift assaIn collaboration with Pär Nordlund, Karolinska Institutet, researchers from Chemical Biology Consortium Sweden at SciLifeLab have published a study in Nature Communications where they demonstrate high throughput screening capability of a method called cellular thermal shift assain Nature Communications where they demonstrate high throughput screening capability of a method called cellular thermal shift assay.

In this assay, total ATP content per well was measured and normalized to the total cellular protein.

This is the first time that that this assay has been used to ascertain retinal function after cellular therapy in a retinal degenerate animal.

We combine biochemical, structural, cellular and functional information using purified proteins, mutant and transgenic plants, yeast and chemical genomic screening systems, transient gene expression assays, confocal microscopy and in silico data analysis to compare ROP - centered kinase signaling during cell polarity (in vitro pollen tubes), morphogenesis (whole plant) and pathogenesis (fungi - infected cells).

These lipases of different cellular origins share a common function and thus can not be differentiated by use of a catalytic assay such as the ones that are being used to determine lipase activity in serum.

Throughout my career I have demonstrated successful Successfully designed and implemented bioassay and cell culture automation strategies, novel cellular uptake and substrate depletion assay methodologies in the pharmaceutical industry.