Sentences with phrase «in cellular behavior»

UB researchers have pinpointed important changes in cellular behavior that occur in Pemphigus Vulgaris, the rare, blistering skin disease shown in this microscopic image.
However, due to technological limitations, previous genetic studies largely focused on mixed populations of cells, obscuring critical nuances in cellular behavior.

Not exact matches

Using what is called «calcium reporters,» researchers were able to see the neurons firing up inside the worm and record the changes in cellular activity during the egg - laying behavior.
So in 1974, he headed south to Tulane University in New Orleans, Louisiana, for graduate training in physiological psychology: the study of how the brain influences behavior at the neurochemical and cellular levels.
And once I got into brain biology, it became clear you needed to study the brain on the cellular level, and once you began to understand aspects of behavior in the cellular level, you wanted to understand the molecular level.
The sea slug was the model organism for Kreiner's thesis research, which explored how cellular mechanisms mediate simple behaviors and led to a publication in Science.
At the cellular level, these disorders are associated with heightened activity in the basolateral amygdala (BLA), which is known to play a central role in emotional behavior.
The changes in cellular structure and behavior were the opposite of what Xu - Friedman team's saw in a previous study that placed mice in a consistently noisy environment.
White is interested in human behavior, but said humans are difficult to study at the cellular and synaptic level.
«In this way, modern supercomputers allow millions of small timesteps of atomic motions to be simulated, getting us to examine the protein but also cellular membrane behavior on the microsecond timescale.»
His research group focuses on big data network biology, exploring biological systems by developing and deploying algorithms aimed to predict cell behavior, in particular looking at cellular signal processing and decision making.
In the past decade, researchers have used mouse models to unravel how cellular changes in the nucleus accumbens (NAc), a brain structure involved in action selection associated with arousal and reward, may contribute to addiction - related behavioIn the past decade, researchers have used mouse models to unravel how cellular changes in the nucleus accumbens (NAc), a brain structure involved in action selection associated with arousal and reward, may contribute to addiction - related behavioin the nucleus accumbens (NAc), a brain structure involved in action selection associated with arousal and reward, may contribute to addiction - related behavioin action selection associated with arousal and reward, may contribute to addiction - related behavior.
These data indicate that cellular metabolic communication plays a critical role in addiction - related behaviors, which may have implications for new strategies to prevent cocaine addiction.
«Our findings fit with the growing appreciation of the importance of a cell's structural and biochemical surroundings in influencing cellular behavior.
A multicellular marine animal without organs, Trichoplax's feeding behavior may include cellular coordination, resulting in external food digestion, according to a study published September 2, 2015 in the open - access journal PLOS ONE by Carolyn Smith and colleagues from the National Institute of Health in Bethesda, MD..
Their observation provides a better understanding of cytoskeletal self - organization in general, which may in turn lead to better drug design and new materials that can mimic cellular behaviors.
Systems biology provides better methods of drug discovery: research teams can measure changes in genetic activity, protein levels and cellular behavior of the immune system in response to a potential vaccine.
Those data were then combined with information about functional changes in cell behavior to develop a nanomechanical profile, or phenotype, for specific cellular states.
Due to these crucial roles in regulating normal cellular behavior, redox status has been recognized as a key area of biological research in various diseases, including cancer.
«What we found at the cellular level correlates with the behaviors we saw in the less - anxious, hyper - active mice, which means having overactive pyramidal neurons with their brakes removed could be contributing to these behaviors,» says Zhu.
More broadly, he said, «These findings are part of an emerging theme that there is a whole spectrum of diseases that includes ALS, and some forms of dementia and myopathy, that are caused by disturbance in the behavior of these structures that perturbs cellular organization.»
Researchers are building a substantial understanding of the biophysical, molecular, and cellular interactions of neurons, but directly relating those interactions to outward behaviors is an ongoing challenge in the field.
Scientists injected fluorescent molecules into about 150 mouse brain structures and used a high - resolution microscope to document the molecules as they moved through the brain's «cellular highways,» which need to be in tip - top shape for different parts of the brain to communicate and coordinate behaviors.
Once they had achieved this precise control over the cellular interactions in the brain, they turned to exploring behavior: Mice that are less fearful are more likely to venture farther than others.
Previous work by Fredberg and colleagues had documented the importance of collective cellular behavior in asthma, showing that cells comprising epithelial tissues — which line the surfaces of all organs throughout the body — can unjam and flow like a fluid, or jam and freeze like a solid.
Dr. Chartoff's Neurobiology of Motivated Behavior Laboratory, founded in 2009, investigates the molecular, biochemical, and cellular mechanisms underlying drug dependence and withdrawal using animal behavioral models with high relevance to the human condition.
The goal is to not only provide broadly applicable experimental tools but also help transform the way in which we think about single cells, cell - cell interactions, diseased cellular states and therapeutics so as to create a new paradigm for understanding and designing systems - level cellular behaviors in multicellular organisms.
Although some of the key molecular components involved in the formation of cellular structures and tissue formation are known, we currently lack a bottoms up understanding of how the behavior of these molecules gives rise to the formation of large structures, partly because of the lack of tools for both studying the spatial regulation of soluble proteins and biophysically characterizing the behavior of large structures and tissues.
These results complement cellular and physiological data and show that dopamine at encoding promotes the prioritization of events in memory, with implications for understanding the role of memory in adaptive behavior.
As a cellular biologist Dr. Pilar Sanchez Gomez has been interested in the molecular mechanisms that control adult neural stem cell (NSC) behavior.
Grillner's experimental and theoretical analysis of motor coordination in the lamprey has served as a standard for other attempts to describe the circuits that encode vertebrate behaviors in precise cellular and anatomical terms.
Since it is still beyond the reach of even the most sophisticated in vitro methodology to simulate the complex interplay of physical, cellular, biochemical, and other factors that influence cell behavior in microvessels and interstitial tissues, we make use of intravital microscopy.
identify molecular, cellular, and anatomical similarities in how these molecules work across species that represent the fundamental principles through which brain neurochemistry affects social behavior in vertebrates.
«In neuroscience, there is a huge black box between genetic information and behavior,» said Krogan, who is also the director of the Quantitative Biosciences Institute and a professor of cellular and molecular pharmacology at the University of California, San Francisco (UCSF).
In my lab, we explore the molecular, cellular, and behavioral mechanisms through which two types of molecules, sex steroids and neuropeptides in the vasopressin / oxytocin family, act within those circuits to influence social behaviors associated with reproductioIn my lab, we explore the molecular, cellular, and behavioral mechanisms through which two types of molecules, sex steroids and neuropeptides in the vasopressin / oxytocin family, act within those circuits to influence social behaviors associated with reproductioin the vasopressin / oxytocin family, act within those circuits to influence social behaviors associated with reproduction.
«Vertical integration of gene function» describes how gene expression initiates a series of biochemical, cellular, and physiological changes that ultimately culminate in an observable behavior.
The level of detail gained in this work was, and still is, unique in that it allows the observation of changes in behavior caused by changing occurring at the cellular and network level.
The cellular mechanisms underlying this bursting behavior have been studied in vitro, using either acute slices of the adult hypothalamus, or organotypic cultures of neonatal hypothalamic tissue.
The authors of the study explain that their findings suggest that ketogenic diets could also potentially help normalize pathological behaviors in the human model of schizophrenia by providing alternative energy sources via ketones, the products of fat breakdown, which would substitute the abnormally functioning cellular energy pathways in the brains of people suffering from this disease.
''... we hypothesize that repeated stress - related allostatic overload may affect brain function at three basic levels: (a) at the cellular level, it may compromise proteostasis (e.g. tau protein), organelles homeostasis, and induce epigenetic changes in neuronal DNA; (b) at the tissue level it may affect intracellular communication (synaptic contacts), number of cells (reduction of neuronal density), composition of the extracellular matrix (accumulation of amyloid plaques), and neuroinflammation; (c) at the systemic levels it may alter the brain's regulation of behavior (cognitive decline).
The concentrated antioxidants found in this amazing red fruit can actually promote and support proper cellular behavior when abnormal cells begin to wreak havoc in the body, especially for men.
At the cellular level, consider the voltage-gated behavior of the sodium channels in a nerve axon or the «negative damping» of hair cells in the cochlea.
In 1998, the Progressive Insurance company started a pilot program in Texas, in which drivers received a discount for installing a GPS - based device that tracked their driving behavior and reported the results via cellular phone to the companIn 1998, the Progressive Insurance company started a pilot program in Texas, in which drivers received a discount for installing a GPS - based device that tracked their driving behavior and reported the results via cellular phone to the companin Texas, in which drivers received a discount for installing a GPS - based device that tracked their driving behavior and reported the results via cellular phone to the companin which drivers received a discount for installing a GPS - based device that tracked their driving behavior and reported the results via cellular phone to the company.
- Improved support for Motorola Moto G Dual SIM: — QS: adjusted network mode tile (allows changing SIM slot on long - press)-- QS: adjusted handling and reordering of cellular tiles — QS: proper adjustment of signal tile size for tiles per row option — Signal cluster adjustments, including icon coloring (NOTE: cell signal doesn't support data activity indicators)-- fixed Smart radio — all other misc Multi SIM related adjustments - Quick settings: — revived Ringer Mode Tile (silent == priority)(thanks to romracer)-- revived USB Tethering Tile — fixed other misc issues in tile management (thanks to romracer)- BatteryBar: improved behavior in lock screen status bar (now allows bottom position)- ProgressBar: improved behavior in lock screen status bar (now allows bottom position)- Phone: — added workaround for missed calls notification LED — added 5s ramp - up duration for ascending ringtone - Ultimate notification control: — fixed issues causing unexpected heads up and notification icon «jumping» — show package names in app descriptions for better identification of packages having the same app name - Power: improved option for low battery warning policy - Navigation bar: improved handling of cursor control keys - Recents: added option for using alternate icon for clear all button - Fixed unexpected disappearing of centered clock and centered traffic monitor - Other misc Motorola specific fixes (thanks to romracer)- Updated Japanese translations (thanks to WedyDQ10)- Updated French translations (thanks to ch - vox)- Updated Hungarian translations (thanks to benjoe1)- Updated Chinese (Simplified) translations (thanks to liveasx)- Updated Portuguese (BR) translations (thanks to wyghor, KingKaminari)- Updated Russian translations (thanks to gaich)- Updated Chinese (Traditional) translations (thanks to PeterDaveHello)- Updated Malay translations (thanks to zamzameir)
This is learnable and can grow in us, as our behaviors are constantly training our nervous systems, even on a cellular level.
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