Sentences with phrase «in cellular compartments»

Divergent lactate dehydrogenase isoenzyme profile in cellular compartments of primate forebrain structures.

Many life forms on our planet produce ATP in cellular compartments called mitochondria.

Not exact matches

A magnified transmission electron microscopy view of the rat nucleus accumbens neurons containing mitochondria in different cellular compartments.

Previous research conducted at Mount Sinai found that the trafficking of protein molecules between the nucleus (the cellular compartment containing the genetic information of the cell) and the cytoplasm is altered in neurodegenerative disease.

Whether in a yeast cell or in a neuron, alpha synuclein directly interfered with the rate of production of proteins in the cell, and the transport of proteins between cellular compartments.

«Cells sequester trash in compartments called autophagosomes» Cells follow a set recipe for recycling: First, the autophagosome is formed around the trash, next autophagosomes are transported and merged with lysosomes — another cellular compartment — and finally, the contents are degraded and either secreted or reused by the cell.

Because the amount of ROS present in cells is tightly regulated by iron - dependent processes in the mitochondria (the cellular compartments in which energy is generated), the researchers had proposed iron import into the mitochondria to be essential for this process.

Dr. Steven R. Goodman, Editor - in - Chief of Experimental Biology and Medicine, said «Kolossov et al have utilized a genetically - encoded redox probe that has the ability to determine oxidized / reduced glutathione levels within different cellular compartments of living cells.

Wolfram syndrome is caused by a mutation in the gene encoding a protein called wolframin, which resides in the membrane of the endoplasmic reticulum — another cellular compartment that functions as a manufacturing and packaging system and also acts as a reservoir for calcium ions.

Using lab - grown mouse astrocytes with variant forms of NHE9, the researchers found a change in the pH (acidity) inside cellular compartments called endosomes, which in turn altered the ability of cells to take up glutamate.

Bits of misfolded proteins processed by specialty organelles may accumulate in the main compartment of the cell, the cytosol, where they can be tagged for disposal by the cellular garbage service.

We investigated the role of Srf in two cellular compartments of mouse skeletal muscle (myofibers and adult muscle stem cells) upon different perturbation of muscle homeostasis (hypertrophy, atrophy, regeneration).

Our moxFPs currently represent one of the most inert solutions for imaging in a variety of cellular compartments including the secretory pathway (Figure 2), the inner membrane space of mitochondria and chloroplasts, the extracellular milieu, and gram negative bacteria periplasm.

This small set of dynamic protein polymer systems underpins the establishment and remodelling of long range cellular order, cell polarity, shape and division, and plays a critical role in control of the dynamic organisation of the internal membrane - bound compartments that distinguish eukaryotes from their prokaryotic ancestors.

The process uses a computational model to generate predictions about the dynamics of cell receptors in different cellular compartments.

It has recently been proposed that the primary role of cellular senescence is in mitotic compartments of fixed size in which spatial considerations dictate that a deleted cell is replaced by a neighboring cell.

The iPS cells are cultured on the opposite side of the membrane in the other channel that represents the glomerulus» urinary compartment, where they are induced to form a layer of mature podocytes that extend long cellular processes through the pores in the membrane and contact the underlying endothelial cells.

«Cells sequester trash in compartments called autophagosomes» Cells follow a set recipe for recycling: First, the autophagosome is formed around the trash, next autophagosomes are transported and merged with lysosomes - another cellular compartment — and finally, the contents are degraded and either secreted or reused by the cell.

These abnormalities coexist with mitochondrial structural alteration and mitochondrial DNA overproliferation and / or deletion in all brain cellular compartments.