They are heavily
involved in cellular metabolism as well as in apoptosis, the process of programmed cell death by which potentially cancerous cells can be killed before they multiply and spread.
Aside from its clinical importance in brain functioning, cobalamin is also involved in the production of red blood cells as well as
aid in cellular metabolism alongside other members of the B - vitamin family.
Agios has leveraged its core
capabilities in cellular metabolism and precision medicine to build a product engine that is focused in the therapeutic areas of cancer and rare genetic diseases.
The two - to four-fold surge in NAMPT in turn triggers the production of a molecule called NAD (nicotinamide adenine dinucleotide), which plays a key
role in cellular metabolism and signaling.
Researchers from the Institut Pasteur, CNRS and Inserm, in collaboration with a team from Switzerland, have discovered a previously unknown mechanism by which L. pneumophila targets mitochondria to modulate mitochondrial dynamics and thereby impairs mitochondrial respiration which in turn leads to a
change in the cellular metabolism.
The mTOR gene is known to play a role
in cellular metabolism and energy balance.
They are involved
in cellular metabolism, DNA repair, metabolism and the production of neurotransmitters and neurohormones in the brain.