Sentences with phrase «in cellular signaling»

Additional upregulated signal transduction related genes encoded proteins polycystin - 1L1, MLP and LIM regulatory proteins, fibrillins or related proteins containing Ca2 + - binding EGF - like domains, Ca2 + / Mg2 + - permeable cation channel, and other differentially expressed putative transcripts that may play a role in cellular signaling, including known extracellular proteins c - type lectin and collagen (see electronic supplementary material, table S5).

[36] Cytokines have been shown to play a major role in the cellular signaling involved in the pathogenesis of breast cancer.

In addition to transporting a wide variety of antibiotic, antiviral, cancer and cardiovascular drugs, MRP4 has the remarkable ability to transport molecules involved in cellular signaling.

He says it's also important to understand the protein's biological role in cellular signaling and normal animal development as well as to consolidate its role in human cancer development, progression and drug - resistance.

We are interested in understanding the molecular mechanisms of proteins involved in cellular signalling, especially protein kinases.

Secondly, magnesium's role in cellular signalling allows it to increase insulin sensitivity and allow the acne - causing hormone insulin to fall.

Moreover, reactive nitrogen and oxygen species (RNOS) are used extensively in cellular signalling, and cells adaptively regulate endogenous antioxidants on short time scales to respond to deletorious spikes of RNOS faster than we could ever achieve with dietary antioxidants.

2017 Commercial Integrator BEST and 2017 CE Pro BEST award winner, Force5 2.0 ™ is the next evolution in cellular signal boosting technology and the # 1 DAS alternative.

Founded in 2001 and based in the Silicon Valley, SureCall is an industry leader in cellular signal booster technology.

Not exact matches

Everybody, everywhere can become a trader as long as they're above 18 years of age, have some extra cash in their bank account, and most importantly, have a great WiFi or cellular data signal.

Most consumers could find it hard to acquire a cellular signal thousands of feet in the air, but recent advancements in technology have made it much easier to get connectivity to previously inaccessible areas such as airplanes.

This allows the company to find the best signal even if the family is in a situation with no cellular coverage and the child has gotten too far away, says Chicago mom of four boys, Lindsay Slutzky, a member of the team.

Cuomo told the MTA to hold a «Genius Award» contest to find the best ideas on how to overcome the seemingly unfixable subway problems of the ancient signal system, the aging fleet of cars, and the lack of cellular and wi - fi connections on trains and in tunnels.

When a smartphone user walks near one of those access points, the receivers recognize their mobile devices and relay a signal to the phones, which in turn transmit the data via cellular networks or Wi - Fi to the place where they are analyzed.

Mitochondria, specialized organelles found in nearly every cell of the body, use cellular respiration to generate one of the most important sources of chemical energy — adenosine triphosphate (ATP), a versatile nucleotide that powers everything from cell division to cell signaling to transportation of large molecules across the cell membrane.

Once there, the protein acts on the osteoblasts and inhibits Wnt activity, which is a cellular signalling pathway that is involved in the formation of the skeleton and in certain disorders, such as osteoporosis, arthritis and myeloma.

She emphasized, however, that lay people need not understand, for example, the mechanics of cellular signaling in order to appreciate the potential importance of those events to human health.

Calcium - based signaling is used in many cellular and neuronal processes to initiate rapid responses to extracellular signals.

When mutated, BRAF, an enzyme that acts in a signaling cascade known as the MAPK / ERK pathway, becomes overactive and leads to increased cellular growth, a hallmark of cancer.

The AXIN2 protein interacts with proteins in the Wnt signalling pathway, which is involved in controlling many cellular processes, including development.

The authors hypothesize that these activities are components of cellular reconfigurations that are involved in processing communication signals essential for social organization.

In addition to diminishing the tumor's energy supply, the diet slows the growth of glioblastoma cells by altering a cellular - signaling pathway that commonly occurs in cancers, according to the researcherIn addition to diminishing the tumor's energy supply, the diet slows the growth of glioblastoma cells by altering a cellular - signaling pathway that commonly occurs in cancers, according to the researcherin cancers, according to the researchers.

HIF - 1 senses reduced oxygen levels and triggers many changes in cellular function, including a changed metabolism and sending signals for the formation of new blood vessels.

They showed that ZIKV infection of cortical progenitors (stem cells for cortical neurons) controlling neurogenesis triggers a stress in the endoplasmic reticulum (where some of the cellular proteins and lipids are synthetized) in the embryonic brain, inducing signals in response to incorrect protein con - formation (referred to as «unfolded protein response»).

The cellular structures behind these messages have not yet been identified, but in the April 1 PLoS ONE, Fels suggests that these signals could lead to novel noninvasive medical techniques.

Science Signaling offers researchers the most up - to - date resource for groundbreaking research and commentary in the multidisciplinary field of cellular sSignaling offers researchers the most up - to - date resource for groundbreaking research and commentary in the multidisciplinary field of cellular signalingsignaling.

The transcription of non-coding regions in the genome is precisely regulated by cellular signaling pathways — and on a grand scale: up to 80 per cent of the RNA copies were non-coding.

But at a basic cellular level, signals are sent and received in strikingly similar ways.

Science Signaling offers groundbreaking research and commentary in the multidisciplinary field of cellular sSignaling offers groundbreaking research and commentary in the multidisciplinary field of cellular signalingsignaling.

Through the mTOR signalling pathway, it is involved in the regulation of many cellular processes, including cell survival, metabolism, proliferation, differentiation, and senescence.

Noticing that both grants and jobs in that field were few, she identified her most readily transferrable skill: her insight into cellular signal transduction.

Those deletions tended to involve genes that affect cilia, cellular structures that are important for signaling and patterning in embryonic development.

The next step in this line of investigation, already in development, is to learn how cellular responses vary, on a molecular level, among roots of flooded plants when the hormone is not present, which would make it possible to create a response model where this signaling path would play a key role.

«The mechanism we demonstrated is the most sensitive cellular thermometer known to date, since the signaling pathways that trigger a heat shock or cold shock hardly react in this physiologically relevant temperature range,» explained Prof. Dr. Florian Heyd.

Researchers from The University of Texas Medical Branch at Galveston have uncovered a cellular signal in the amniotic fluid around the fetus that builds up when a pregnant woman is about to go into labor.

Some researchers speculate that fatty acids help maintain fluidity in the cellular membranes, allowing neural receptors to better detect incoming signals.

The team of UW computer scientists and electrical engineers eliminated a power - hungry step in most modern cellular transmissions — converting analog signals that convey sound into digital data that a phone can understand.

The article «EGFR signalling controls cellular fate and pancreatic organogenesis by regulating apicobasal polarity» has been published in Nature Cell Biology.

«Calcium signaling regulates many important cellular functions, like muscle contraction, neural communication, gene transcription and tissue growth,» said Fenfang Li, a postdoctoral research fellow in Zhong's laboratory and lead author of the study.

His research group focuses on big data network biology, exploring biological systems by developing and deploying algorithms aimed to predict cell behavior, in particular looking at cellular signal processing and decision making.

In 2014, Dr. Linding moved his laboratory to the Biotech Research and Innovation Centre (BRIC) at University of Copenhagen where he is currently professor of cellular signaling.

Dr. Linding then established his own laboratory of Cellular & Molecular Logic at the Institute of Cancer Research (ICR) in London, UK, before returning to Denmark to take a position as professor of cellular signal integration at the Technical University of Denmark.

In prior, unrelated experiments, the same species of worm had become hypersensitive to smell when its nerve cells experienced problems with dopamine signaling, a cellular process that helps control how readily cells can communicate with one another.

The budding yeast, Saccharomyces cerevisiae, is a prime organism for studying fundamental cellular processes, with the functions of many proteins important in the cell cycle and signaling networks found in human biology having first been discovered in yeast.

It thus seems quite likely that this new signaling path also links the performance of the cellular power plants and cell division in human cells,» says Meisinger, who now plans to analyze these mechanisms in tumor tissues.

At a minimum, the result is an incredibly complex web of cellular signals that are constantly working together (or in opposition, as the case may be) to adjust the number and type of proteins expressed in a cell and so, ultimately, the health of the cell itself.

Most importantly, when the team disabled the HIF - 1α cellular alarm, BMP signaling in human FOP bone progenitor cells was restored to levels comparable to cells in normal oxygen.

«Signal in may send cancer's cellular factories into overdrive.»

With entry categories for science / healthcare workers and the under 25s as well as professional and amateur photographers, the competition is an opportunity to stimulate an interest in any area of science, from planetary movements to cellular signalling or more general topics such as physics or the environment, as well as demonstrating artistic flair.

What scientists once thought was unremarkable cellular «noise» in neuron signaling has come to be viewed as important to overall system - wide functioning in the brain.