Sentences with phrase «in coding region»

One of these is a variable number 48 base pair tandem repeat (48 bp VNTR) in the coding region of the gene [89].

One SNP, c. 1175G > A, in the coding region was observed to lead to the substitution p.Gly392Ser.

In addition, in a series of cardiac biopsies from 131 individuals with DCM, we found 5 individuals with 4 previously unreported non-synonymous variants in the coding region of PRDM16.

Copy number variation (CNV) is a common chromosomal alteration that can occur during in vitro cultivation of human cells and can be accompanied by the accumulation of mutations in coding region sequences.

Although the researchers found no change in the coding region of the gene, they did find that autistic children were much more likely to have inherited a shortened form of the genes promoter — the DNA sequence that serves as the on ramp for the cellular machinery that will express the gene.

Using this analysis, the researchers identified deletions in the coding region of the gene (in exons E2 to E9, E5 to E9, E8, E10, E14, and E1 to E15), duplications (E11 to E12) on two chromosomes, and a nonsense mutation.

For example, more than 33 % of the base changes they found in coding regions also alter its protein product.

To resolve this paradox, we analyzed introns and demonstrated that these are deficient in single - nucleotide polymorphisms, as are synonymous sites in coding regions.

The observed mutation rate in coding regions seems to reflect the aggressiveness of breast cancer subtypes: lower in luminal A (0.84 mutations / Mbp) than luminal B (1.36 mutations / Mbp), higher in Her2 - enriched (2.05 mutations / Mbp) and Basal - like (1.68).

Even more astonishing are the 6 + million coding variants: depending on how you define the exome, that's about one variant every 5 or 6 base pairs in coding regions.

Not exact matches

Akins said that the new tax code, combined with federal deregulation, would drive growth in his company's main operating region between Texas and Ohio.

Regions are divided on «changing employee dress codes» to attract digital talent — it is not a widely adopted tactic in the Middle East or Africa.

The average price of a condo in the city of Toronto was $ 366,532 while one in the outlying areas known as the «905» region after the local telephone area code, is priced at $ 288,604.

Babylonia, situated on a broad low plain between the rivers at their widest points, was very fertile and had developed an advanced culture as early as 3500 B.C.. From this region comes the famous Code of Hammurabi which, dating from long before the time of Moses, shows high ethical discernment regarding the establishment of justice in human relations.

Regarding «Junk DNA,» yes, previous assumptions about the role of non-coding DNA have been replaced with an appreciation for other roles in regulation of coding regions, but this simply doesn't support the notion that our genomes were intelligently designed.

Kelsey Trail Health Region in Northern Saskatchewan put up its annual WBW display, this year based on the theme of the 25th anniversary of the International Code.

Feeding and nutrition of infants and young children (2003) Guidelines for the WHO European region, with emphasis on the former Soviet countries Development of a global strategy on infant and young child feeding: report on a WHO / UNICEF consultation for the WHO European Region (2001) Budapest, Hungary 28 May - 1 June 2001 Comparative analysis of implementation of the Innocenti Declaration in WHO European member states (1999) Monitoring Innocenti targets on the protection, promotion and support of breastfeeding Breastfeeding and healthy eating in pregnancy and lactation (1998) Report on a WHO workshop, Arkhangelsk, Russian Federation, 5 - 8 October 1998 Breastfeeding: how to support success (1997) A practical guide for health workers Health workers and the WHO International Code of Marketing of Breast - Milk Substitutes (1987) Report on a WHO meeting, Copenhagen, 31 October 198region, with emphasis on the former Soviet countries Development of a global strategy on infant and young child feeding: report on a WHO / UNICEF consultation for the WHO European Region (2001) Budapest, Hungary 28 May - 1 June 2001 Comparative analysis of implementation of the Innocenti Declaration in WHO European member states (1999) Monitoring Innocenti targets on the protection, promotion and support of breastfeeding Breastfeeding and healthy eating in pregnancy and lactation (1998) Report on a WHO workshop, Arkhangelsk, Russian Federation, 5 - 8 October 1998 Breastfeeding: how to support success (1997) A practical guide for health workers Health workers and the WHO International Code of Marketing of Breast - Milk Substitutes (1987) Report on a WHO meeting, Copenhagen, 31 October 198Region (2001) Budapest, Hungary 28 May - 1 June 2001 Comparative analysis of implementation of the Innocenti Declaration in WHO European member states (1999) Monitoring Innocenti targets on the protection, promotion and support of breastfeeding Breastfeeding and healthy eating in pregnancy and lactation (1998) Report on a WHO workshop, Arkhangelsk, Russian Federation, 5 - 8 October 1998 Breastfeeding: how to support success (1997) A practical guide for health workers Health workers and the WHO International Code of Marketing of Breast - Milk Substitutes (1987) Report on a WHO meeting, Copenhagen, 31 October 1986 WPRO

The proportion of countries with comprehensive legislation in line with the Code was highest in the WHO South - East Asia Region (four out of 11 countries), followed by the African Region (14/47 countries), the Eastern Mediterranean Region (6/21), the Region of the Americas (8/35), Western Pacific Region (4/27) and the European Region (3/53).

With the results for all constituencies and regions in Scotland in, BASC - the largest shooting association in Scotland - has announced that it has identified 48 out of 129 (37 %) members of Scottish Parliament (MSPs) from all parties except the Greens who are supportive of shooting according to the current law and codes of practice.

«The so called military operations code named «OPERATION PULO SHIELD» in the Niger Delta region who our partners in the oil bunkering activities, because presently without been told the former JTF Commander, Major - General Emmanuel Atewe who was arrested by the EFCC last week over pipelines surveillance contract amounts to N8.2 billion in the region, is an eye opener to the federal government that the military are fully involved in illegal bunkering in the area.

While unemployment in Erie County as a whole is comparable to other metropolitan regions in the United States, the unemployment rate within certain zip codes located in Erie County is as high as 21.7 % and the poverty rate as high as 44.7 %; these zip codes are among the 16 targeted for attention by the Executive Order.

The educators are taking classes such as «Discover Coding in Our Everyday Lives» and «Connecting the Polar Regions to Climate Change,» to supercharge their science lessons.

Many Party members will take the same line as LabourList and want to convince themselves that elections in our Party are fair and above board.Sadly this is not the case.Last year after the CAC Election a number of delegates, from several different Regions, came forward and said full time officials encouraged them to vote against Katy and myself.This is totally against the Code of Conduct and, to me, is little different to ballot rigging.An investigation is underway.We have a good idea who was behind it.LeftFutures will keep you updated.

I am a member of the Chartered Institute of Public Relations — and a finalist or the 2012 CIPR PRide Awards in the Eastern Region — and adhere to their professional Code of Conduct.

WAMC's David Guistina talks with Mike Spain of the Times Union about a code blue shelter in Saratoga and delayed propane deliveries around the Capital Region.

Commander of the JTF in Niger Delta, Rear Admiral Suleiman Apochi who made this known in a statement, said, «In line with the Joint Task Force (JTF) Operation Delta Safe (OPDS) mandate to protect critical Oil and gas facilities in the Niger Delta region, a deliberate operation code named Op Ember Safe was conducted by the Forcin Niger Delta, Rear Admiral Suleiman Apochi who made this known in a statement, said, «In line with the Joint Task Force (JTF) Operation Delta Safe (OPDS) mandate to protect critical Oil and gas facilities in the Niger Delta region, a deliberate operation code named Op Ember Safe was conducted by the Forcin a statement, said, «In line with the Joint Task Force (JTF) Operation Delta Safe (OPDS) mandate to protect critical Oil and gas facilities in the Niger Delta region, a deliberate operation code named Op Ember Safe was conducted by the ForcIn line with the Joint Task Force (JTF) Operation Delta Safe (OPDS) mandate to protect critical Oil and gas facilities in the Niger Delta region, a deliberate operation code named Op Ember Safe was conducted by the Forcin the Niger Delta region, a deliberate operation code named Op Ember Safe was conducted by the Force.

Compared with mutations in protein - coding regions, variants in regulatory regions usually have «smaller but additive effects.

Dr. Jackson has also been instrumental in the development of a Code of Conduct for chemists in the Middle East — a critical step in helping to create a weapons - of - mass - destruction - free zone in the region.

All of this makes for a headache for those trying to sort out appropriate building codes and engineering designs; to try to bring some harmony to the dispute, the latest hazard assessment incorporated a model that followed some of Stein's ideas, including using GPS to detect tectonic strain in the region, as well as the data from NRC.

Mark Rosen, senior legal adviser at CNA Corp. who is not affiliated with environmental groups, said there should be a requirement in the code that ships operating in polar regions carry a certain level of insurance, based on their cargo.

It is preparing the final draft of the «polar code,» which if enacted would be the first comprehensive mandatory rules for commercial ships in polar regions.

The team integrated three, complementary gene sequencing approaches to look for mutations in tumor cells from SS patients: whole - genome sequencing in six subjects, sequencing of all protein - coding regions (exomes) in 66 subjects, and comparing variation in the number of copies of all genes across the genome in 80 subjects.

Standard mapping procedures depend on homing in on informative coding regions in genes and «walking» along the chromosome, past any uninformative repetitive DNA, to the next gene.

Kingsley's research has shown that these adaptive changes are often driven by changes in the regulatory regions that surround and control gene expression, rather than within the coding regions of the genes themselves.

The gene (E2A) that codes for proteins with the properties of immunoglobulin enhancer binding factors E12 / E47 was mapped to chromosome region 19p13.2 - p 13.3, a site associated with nonrandom translocations in acute lymphoblastic leukemias.

The new study, published this month in the journal The Leading Edge, provides a color - coded map of the 75,000 - square mile region that identifies those potential oil and gas development sites that would be would be most likely to trigger an earthquake associated with fluid injection.

«There is increased interest in enhancers and eRNAs in the cancer biology world because defective enhancers can cause too much or too little of a protein to be made, or can cause the coding region to be turned off or on, or can make a protein at the wrong time,» Berger said.

«This is understandable in some regions where less developed countries face competing pressures for limited financial resources, but it is notable that this threat is not addressed in design codes for at - risk European countries,» the final paper says.

Pugh added that the implications of this research could represent one step towards solving the problem of «missing heritability» — a concept that describes how most traits, including many diseases, can not be accounted for by individual genes and seem to have their origins in regions of the genome that do not code for proteins.

Nobody knows why an invertebrate should need such a gene, but the fact that its various coding regions are organised in a subtly different way from those of all other known globin genes is forcing a rethink about the evolutionary history of globin genes.

In the new study, the researchers show that Stau2 binds specifically to a so - called intron sequence found near the end of a specific subset of mRNAs — in a region that contains no coding information, but serves a regulatory function insteaIn the new study, the researchers show that Stau2 binds specifically to a so - called intron sequence found near the end of a specific subset of mRNAs — in a region that contains no coding information, but serves a regulatory function insteain a region that contains no coding information, but serves a regulatory function instead.

In about 70 percent of the cases, he found a dislocation in a particular region of a certain chromosome, but at first he could not find any protein - coding gene responsiblIn about 70 percent of the cases, he found a dislocation in a particular region of a certain chromosome, but at first he could not find any protein - coding gene responsiblin a particular region of a certain chromosome, but at first he could not find any protein - coding gene responsible.

Nahata's team used terahertz radiation to read the coded information because the wavelengths in this region are best suited for imaging the resolution available from commercial inkjet printers.

It had a microRNA hidden in one of its introns,» the region of DNA that doesn't code for proteins.

To get a clearer picture of the settlement patterns, David Reich of Harvard Medical School in Boston and his colleagues compared DNA from 52 Native American populations across Canada, Greenland and Central and Southern America, focusing on variations called single - nucleotide polymorphisms (SNPs) in protein - coding and non-coding regions across the genome.

The mutation isn't in a region of the gene that codes for the SMARCAD1 protein; instead it's near a key splicing site that prevents SMARCAD1 from being made correctly, the researchers report today in The American Journal of Human Genetics.

Nix and Rais - Bahrami say this new technology offers a «targeted biopsy,» which refers to direct tissue sampling of suspicious areas seen on MRI as opposed to the traditional method of random, systematic sampling that is essentially performed «blindly» in different «ZIP code» regions of the prostate.

This site is within the coding region of a gene that's «aberrantly expressed» in a form of childhood leukemia, Fischer says.

Using whole exome sequencing (a next generation test to analyze the exons or coding regions of thousands of genes simultaneously) conducted at the Baylor College of Medicine Human Genome Sequencing Center, the researchers identified CLP1 mutations in two unrelated families with the disorder.

Previous work had shown that the DNA region in question, a promoter located on chromosome 17, switches on a nearby gene coding for a protein that shuttles serotonin back into nerve cells so they can reuse it as a neurotransmitter.