Sentences with phrase «in contractile»

The greater gains in strength - to - size that result from an increase in specific tension are not reflected in improvements in muscle power, because the reduction in contractile velocity counteracts the effects of the increased muscle fiber force (Erskine et al. 2011).

Myofibrillar hypertrophy is an increase in the contractile component of the cell.

When looking at the whole muscle, this decrease is more than outweighed by gain in contractile strength and power.

Consequently, any change in the contractile behaviour of the plantarflexor muscles induced by long - term use of HH might indirectly also affect tendon mechanical properties.

Studies have shown an increase in contractile force of our TA and PF muscles when activated together vs. contracting individually.

The shortened tissues become compressed and dehydrated and this leads to a decrease in contractile strength.

Hypertrophy is an increase in the different size dimension of muscular fibers, whether in terms of size increases in the contractile or non-contractile fibers of muscle tissue.

The soreness is known as DOMS — delayed - onset muscle soreness and it happens as a result of micro tears in the contractile proteins as well as the muscle cell membrane.

Modeling of PRDM16haploinsufficiency and a human truncation mutant in zebrafish resulted in both contractile dysfunction and partial uncoupling of cardiomyocytes, and also revealed evidence of impaired cardiomyocyte proliferative capacity.

No differences in contractile parameters were observed in soleus muscles from IL - 15Rα — KO mice (Supplemental Figure 2 and Table 2) or when comparing contractile parameters in muscles from IL - 15 — KO mice and BL / 6NTac control mice or HSA - IL - 15TG mice and HSA - IL - 15Con mice (data not shown).

Not exact matches

In this research, Yousaf and his team made a scaffold free beating tissue out of three cell types found in the heart — contractile cardiac muscle cells, connective tissue cells and vascular cellIn this research, Yousaf and his team made a scaffold free beating tissue out of three cell types found in the heart — contractile cardiac muscle cells, connective tissue cells and vascular cellin the heart — contractile cardiac muscle cells, connective tissue cells and vascular cells.

«I thought, «why would capillaries contract, when conventionally arteries are the main contractile vessels, and why should dietary amino acids circulating in the blood cause these contractions?»»

Dilated cardiomyopathy is a relatively common disease in which the heart enlarges and loses contractile strength.

Staining on these slides shows that engineered human arteries produce contractile proteins (left) and calponin (right) just one week after being grown in culture.

The tissue, called the stroma, includes fat cells, or adipocytes, that provide padding; fibroblasts, which make the framework for tissue; pericytes in blood vessels, which are contractile cells that help regulate blood pressure; as well as myoepithelial cells comprising the outer layer of the ductal system through which milk flows.

The new study shows that the proportion of patients with a severely deteriorated heart contractile function is much less (60 %) in the group that received metoprolol.

The investigators then used mass spectrometry to home in on the particular regions in each protein to which the anesthetics were bound and these turned out to be domains that are critical for the proteins» contractile function.

Case Western Reserve researchers already demonstrated that a single protein plays a pivotal role in the use of nutrients by major organs that allow for the burning of fat during exercise or regulating the heart's contractile and electrical activity.

But when physiologist H. Lee Sweeney of the University of Pennsylvania School of Medicine in Philadelphia and his colleagues put this faulty gene into embryonic quail muscle cells growing in lab dishes, the cells made a shortened version of the protein and incorporated it into their contractile machinery.

The contractile activity of smooth muscle cells in the walls of cerebral arteries determines the degree of constriction they experience (known as arterial tone) and thereby controls blood flow.

«In this study, we developed a novel method for controlled crumpling of graphene and graphite via heat - induced contractile deformation of the underlying substrate,» explained Michael Cai Wang, a graduate student and first author of the paper, «Heterogeneous, Three - Dimensional Texturing of Graphene,» which appeared in the journal Nano LetterIn this study, we developed a novel method for controlled crumpling of graphene and graphite via heat - induced contractile deformation of the underlying substrate,» explained Michael Cai Wang, a graduate student and first author of the paper, «Heterogeneous, Three - Dimensional Texturing of Graphene,» which appeared in the journal Nano Letterin the journal Nano Letters.

Muscle contractile properties were examined in the EDL and soleus muscles.

These morphological data highlight a unique feature of fast muscles that are IL - 15Rα deficient, which likely contributes to the slower contractile characteristics we observed in these normally fast muscles.

The observation of reduced calsequestrin in the muscles of IL - 15Rα — KO mice is interesting inasmuch as calsequestrin concentrations are reported to be higher in fast muscles (52) and fast muscles from calsequestrin - 1 — null mice display contractile characteristics similar to those of slow muscles, including longer contraction times and half - relaxation times (ν RTs)(53).

Because the phenotypes were distinct in these knockout mouse models with respect to spontaneous cage activity and fast muscle isometric contractile characteristics, we can conclude that the roles of IL - 15Rα and IL - 15 in vivo are distinct with regard to muscle function.

In vitro experiments in myogenic cells initially suggested that IL - 15 was an anabolic factor for skeletal muscle, able to stimulate the accumulation of contractile protein in differentiated myotubes (8 — 10In vitro experiments in myogenic cells initially suggested that IL - 15 was an anabolic factor for skeletal muscle, able to stimulate the accumulation of contractile protein in differentiated myotubes (8 — 10in myogenic cells initially suggested that IL - 15 was an anabolic factor for skeletal muscle, able to stimulate the accumulation of contractile protein in differentiated myotubes (8 — 10in differentiated myotubes (8 — 10).

On this basis, we propose that IL - 15Rα has a role in determining the contractile and morphological phenotypes of fast skeletal muscles in vivo.

Clara Franzini — Armstrong writes about Annemarie Weber, «a major contributor to the renaissance of muscle biology research in the 1950s to 1970s, when the components of the contractile machinery were identified; novel views of muscle contraction and regulation were elucidated; and principles of energy transduction, motility and intracellular signaling common to all cells were revealed.»

For example, he explains, smooth muscle cells grow thicker in large blood vessels like arteries, but similar type of contractile cells begin to die off in tiny blood vessels in the eye.

The understanding of this group of disorders has advanced in recent years through the identification of the causative mutations in the gene encoding one of the major proteins of the basic contractile unit of skeletal muscle, i.e., actin.

Nrf2 modulates contractile and metabolic properties of skeletal muscle in streptozotocin - induced diabetic atrophy.

An anthelmintic drug, pyrvinium pamoate, thwarts fibrosis and ameliorates myocardial contractile dysfunction in a mouse model of myocardial infarction.

Their contribution to the formation and maintenance of the contractile apparatus highlight an unconventional role for clathrin flat lattices in skeletal muscle which may be relevant to pathophysiology of several neuromuscular disorders.

It is thought that using HRT, at least in part, reduces modifications of muscle contractile proteins that are linked to ageing.»

Organ bath experiments for detecting contractile response in rat uterus 2.

Oxytocin - and NAADP - mediated effects were investigated by using contractile measurements of whole uterine strips from rat in organ baths.

Finally, in a collaboration with Frank Jülicher's group at the Max Planck Institute for the Physics of Complex Systems, we are using these data to develop physical models that will help us understand how local cellular adhesive, elastic and contractile properties are influenced by PCP proteins and other molecules, and how they combine to produce specific packing geometries at a global level.

Unlike inanimate matter, cells contain molecular force generators that produce active contractile stresses in the cellular material.

Here we study the effect of contractile forces originated from model tumor spheroids embedded in a biomimetic collagen I matrix.

Some of the recognized challenges are poor engraftment of implanted cells and, in the case of human cardiomyocytes, functional immaturity and lack of electrical integration, leading to limited contribution to the heart's contractile activity and increased arrhythmogenic risks.

These different contractile properties result in the self - organised sorting of the cells in either inner or outer position.

Ancestral state reconstruction suggests that contractile mesodermal midline cells existed in bilaterian ancestors.

Regardless of its nature, dorsoventral axis inversion (35) would have brought the ventral midline tissue into a dorsal position in the chordate lineage, and the appearance of incompressible vacuoles (14) would have gradually transformed it into a stiff rod of constant length; the amphioxus notochord could then be regarded a vestige of a contractile - cartilaginous transition.

Interestingly, these cyclic contractile events are conserved in evolution and can take various forms.

Strength training has an undisputable good record for providing benefits such as increased muscle fiber size, increased muscle contractile strength, increased tendon strength and increased ligament strength, in people who train consistently (more than twice per week) for 12 weeks.

And concerning the tissue which is involved with the neural drive, this would theoretically occur in a direct response for the requirement of contracting the cells via the hypertrophied contractile mechanisms.

for example, if you were to do a biceps curl with a dumbbell, the load is at its maximum when your forearm is parallel to the earth; that is about mid-range with relation to the sliding (contractile) filaments in the muscle.

A review over low carb diets revealed that «Complications such as heart arrhythmias, cardiac contractile function impairment, sudden death, osteoporosis, kidney damage, increased cancer risk, impairment of physical activity and lipid abnormalities can all be linked to long - term restriction of carbohydrates in the diet.»

This is known as myofibrillar hypertrophy, in which the contractile unit of the muscle gets stronger and larger, ultimately leading to greater force production.

When you build for bulk, you actually increase the fluid in the space between the strands, inflating the size of the muscle without increasing its contractile capacity.