Sentences with phrase «in culture dishes»

Manipulating genes and then sorting through many cells to find the desired alterations wasn't possible with these cells because scientists couldn't grow them in the culture dishes where such maneuvers would take place.

The colonies were fixed in culture dishes with 4 % paraformaldehyde in phosphate - buffered saline (0.01 M PBS, pH 7.4) for 20 min at room temperature (RT) followed by washing with PBS (2 × 5 min).

The scientists explored this possibility in mouse neurons grown in culture dishes.

The researchers showed that inhibiting SIRT1 increased levels of both the acetylated tau and the p - tau in neurons grown in culture dishes.

Spike and Gray grew the mammary stem cells in culture dishes and stained them so that new stem cells appeared a different color from differentiated mammary cells.

In culture dishes, ramping up the expression of just four genes can turn skin and other cells into so - called induced pluripotent stem (iPS) cells.

They have spread lies about his methods, accused him of electrocuting monkeys when in fact he was working with cells in culture dishes, and limited his job opportunities.

Sheltzer, who began his project in the laboratory of Dr. Angelika Amon at MIT and carried it to conclusion in his own research group at CSHL, placed two sets of otherwise identical cells in culture dishes, side by side.

The investigators studied application of various doses of a common PBDE flame retardant on human adrenal cells in culture dishes and compared the effects with those of only the vehicle, the inactive substance used to deliver the chemical.

They then grew the mammary buds in culture dishes for five days.

In a culture dish microglia that were modified to make a lot of TREM2 gobbled more amyloid and removed more dying neurons, compared with microglia having less of the protein.

In 2000 Michael Elowitz, now 38, designed a genetic circuit that made E. coli blink in a culture dish.

They studied H. pylori bacteria in a culture dish and compared the effect of only the antibiotic metronidazole against the bacteria versus the prodrug system with metronidazole and carbon monoxide combined.

But observing what goes wrong when a gene is missing is easier than learning to orchestrate differentiation in a culture dish.

CELLS GONE WILD Turning off the gene Apc in mouse intestinal cells in a culture dish spurs out - of - control cell growth (left panel, pink).

In one study, published today in PLoS ONE, the researchers grew rat neurons in a culture dish and then attached them to a sheet of stretchy polymer.

Moving forward, he was able to place these taste stem cells in a culture dish and prompt them to grow into the different mature taste cell types, thus creating a taste bud in a dish — scientifically known as taste organoids.

Adoptive cell transfer procedures are mimicking exactly this process in a culture dish by taking T cells from patients, multiplying them, sometimes genetically modifying them, and then returning them to patients so that they can, for example, locate and kill cancer cells.

The researchers, led by University of California, San Diego neuroscientist Mark Tuszynski, took skin cells from the patients, grew them up in a culture dish and genetically engineered them to make human nerve growth factor (NGF).

Researchers in Japan have made fertile mammalian sperm in a culture dish, a feat long thought to be impossible.

The patient, already in a wheelchair, visited the lab and watched in amazement as his own muscle cells beat in a culture dish after corrective editing.

One major roadblock, Miglietta told me, is that most of the work on transcription factors has been done on cells grown in a culture dish.

Investigations into human brain development using human cells in the culture dish have so far been very limited: the cells in the dish grow flat, so they do not display any three - dimensional structure.

Benjamin Reubinoff, Tamir Ben - Hur, and their colleagues at Hadassah University Hospital in Jerusalem, Israel, and Monash University in Melbourne, Australia, took a simpler approach, letting the stem cells multiply in a culture dish until they differentiated on their own.

Normally, CD4 cells will start dividing when they are treated with certain proteins in a culture dish.

By adding a combination of four key factors, a skin cell can be made into an iPSC, which can then be coaxed into forming liver, lung and brain cells in a culture dish.

Reprogramming in living tissues is not only possible, «it's even better» than in a culture dish, Serrano says.

Bailey now uses imaging technology to observe the changes in the synaptic connections in single motor neurons, as they are subjected to physiological stimulation in a culture dish.

This information could then be used to prompt embryonic stem cells to differentiate in the culture dish into neurons for potential use in cell - replacement therapy.

Figure 1: New progenitor cells produced from existing cells in the eye growing in culture dish.

Isolated salamander heart cells will divide in a culture dish, and scientists are trying to understand the mechanics of this cell division.

Because neurodegenerative disorders like PD are largely diseases of aging, modeling them in a culture dish using neurons grown from iPS cells has been thought to be exceedingly difficult, if not impossible.

I firmly believe that basic knowledge is absolutely necessary; if we are going to be able to repair injured retinas, we need to know how different retinal cells are made normally, so we can remake them in a culture dish and use them to replace injured retinal cells.

In this process, a couple's sperm and eggs are fertilized in a culture dish.

Testicular tissue exposed to painkillers in a culture dish had around a quarter fewer sperm - producing cells after exposure to paracetamol or ibuprofen.

We came across a compound that had been isolated from a plant species and shown to have effects on blocking the growth of blood vessel cells, both in the culture dish and also in animal models.

This is basically tweaking the molecules: making small chemical changes to the compound in hopes of finding something that could block the growth of blood vessel cells initially in the culture dish without having toxic effects on other cell types.

The cell types involved in diabetes — the beta and immune cells — are being studied in the culture dish, as well as transplanted into lab animals.

After a very extended childhood spent dividing in a culture dish, even stem cells tend to grow up and assume adult roles as workaday nerve, muscle, or blood cells, never to return to their youthful state.

In a study published earlier this year, the same Belmonte and Gage lab team demonstrated that a few ES cells in a culture dish tended to lose stemness and evolve into muscle cell precursors, most likely goaded by a muscle differentiation factor known as BMP.

Not exact matches

Applied to cell cultures in a petri dish, it works.

When U.K. television recently aired footage of three foodies tasting meat formed from approximately 20,000 thin strips of cultured muscle tissue in a Petri dish, viewers were witnessing a breakthrough that raises both hope and concern.

A cell in my brain is different from a cell not in my brain but, say, in a culture of cells in a dish.

Smørrebrød — an open - faced rye sandwich piled high with toppings — is one of the most essential dishes in the Danish culture, most commonly eaten for...

This is a combo of cultures in a South American Dish.

Everyone brings a dish to share so lunch is always a beloved mish - mash of cultures — last year my mum's soya sauce duck with Chinese mushrooms fought for space on the overloaded table with my Auntie R's traditional roast turkey, my sister in law's clove - studded ham, our friend's Malaysian lamb curry, king prawns, oysters, my ex's German coleslaw and potato salad, noodles, smoked fish and quinoa salad brought by friends and my dad's famous lobster noodles.

This dish is inspired by the smoked herring culture on the island of Bornholm in Denmark.

Discovering dishes from different cultures, exploring new flavor combinations, and simply stuffing her face on some homemade comfort food are definitely past times that make her top five — along with scribbling about them in her notebook.

In addition to the delicious day - to - day options, guests can indulge in Wednesday Ethnic Inspirations tasting menus, which feature dishes that celebrate numerous cultures of cuisine, as well as afternoon tea times with dessertIn addition to the delicious day - to - day options, guests can indulge in Wednesday Ethnic Inspirations tasting menus, which feature dishes that celebrate numerous cultures of cuisine, as well as afternoon tea times with dessertin Wednesday Ethnic Inspirations tasting menus, which feature dishes that celebrate numerous cultures of cuisine, as well as afternoon tea times with desserts.

Located in the fashionable Heddon Street food quarter, off Regent Street, tibits restaurant offers over 40 delicious, healthy and filling dishes inspired by cultures from around the world, including hot dishes, salads, soups, desserts, smoothies, cocktails, wines and beers.