Sentences with phrase «in deacetylation»
Not exact matches
PARP family members are also NAD + - consuming enzymes which degrades NAD + in NAM and O - acetyl ADP ribose by sirtuin mediated deacetylation.
http://www.cellr4.org/
Valproic acid reduces histone deacetylation, in effect promoting acetylation, as the oncogene does.
Silencing of the Oct4 promoter in P19 cells is a complex process, mediated by a combination of events including orphan receptor binding, DNA methylation, histone deacetylation, and heterochromatin formation [36], [37].
The increase in intracellular NAD elicited by CD38 deletion significantly activated SIRT1 and prompted clinical phenotypes similar to those expected for SIRT1 activation, including protection against diet - induced obesity and a robust deacetylation of SIRT1 targets.