Sentences with phrase «in decreased ability»

When seen, this occurs 7 - 10 days after the vinblastine treatment, and can result in decreased ability to fight infection and can possibly inhibit the blood's ability to clot resulting in bleeding.

Seen 7 - 10 days after and sometimes up to 16 days after treatment — resulting in decreased ability to fight infection, and possibly bleeding.

Canine dilated cardiomyopathy (DCM) is a primary disease of cardiac muscle that results in a decreased ability of the heart to generate pressure to pump blood through the vascular system.

Low white blood cell counts — if seen, occurs 7 - 10 days after treatment, and can result in decreased ability to fight infection.

Not exact matches

I expect, however, that there will be three first - order effects that will be very similar to those that followed the BP spill: 1) increased public consciousness of the dangers inherent in transporting oil and oil products and more aversion to having these products moved nearby; 2) increased calls for alternatives to oil rather than alternative means of transporting oil; and 3) decreased trust in regulators» and firms» abilities to sufficiently mitigate risks from transporting oil.

Beyond that the adrenal gland responsible for secreting the stress response hormone becomes fatigued, resulting in decreased immunity to infection, reduced ability to repair the body and increased inflammation and tissue damage.

These risks and uncertainties include: Gilead's ability to achieve its anticipated full year 2018 financial results; Gilead's ability to sustain growth in revenues for its antiviral and other programs; the risk that private and public payers may be reluctant to provide, or continue to provide, coverage or reimbursement for new products, including Vosevi, Yescarta, Epclusa, Harvoni, Genvoya, Odefsey, Descovy, Biktarvy and Vemlidy ®; austerity measures in European countries that may increase the amount of discount required on Gilead's products; an increase in discounts, chargebacks and rebates due to ongoing contracts and future negotiations with commercial and government payers; a larger than anticipated shift in payer mix to more highly discounted payer segments and geographic regions and decreases in treatment duration; availability of funding for state AIDS Drug Assistance Programs (ADAPs); continued fluctuations in ADAP purchases driven by federal and state grant cycles which may not mirror patient demand and may cause fluctuations in Gilead's earnings; market share and price erosion caused by the introduction of generic versions of Viread and Truvada, an uncertain global macroeconomic environment; and potential amendments to the Affordable Care Act or other government action that could have the effect of lowering prices or reducing the number of insured patients; the possibility of unfavorable results from clinical trials involving investigational compounds; Gilead's ability to initiate clinical trials in its currently anticipated timeframes; the levels of inventory held by wholesalers and retailers which may cause fluctuations in Gilead's earnings; Kite's ability to develop and commercialize cell therapies utilizing the zinc finger nuclease technology platform and realize the benefits of the Sangamo partnership; Gilead's ability to submit new drug applications for new product candidates in the timelines currently anticipated; Gilead's ability to receive regulatory approvals in a timely manner or at all, for new and current products, including Biktarvy; Gilead's ability to successfully commercialize its products, including Biktarvy; the risk that physicians and patients may not see advantages of these products over other therapies and may therefore be reluctant to prescribe the products; Gilead's ability to successfully develop its hematology / oncology and inflammation / respiratory programs; safety and efficacy data from clinical studies may not warrant further development of Gilead's product candidates, including GS - 9620 and Yescarta in combination with Pfizer's utomilumab; Gilead's ability to pay dividends or complete its share repurchase program due to changes in its stock price, corporate or other market conditions; fluctuations in the foreign exchange rate of the U.S. dollar that may cause an unfavorable foreign currency exchange impact on Gilead's future revenues and pre-tax earnings; and other risks identified from time to time in Gilead's reports filed with the U.S. Securities and Exchange Commission (the SEC).

These risks include, in no particular order, the following: the trends toward more high - definition, on - demand and anytime, anywhere video will not continue to develop at its current pace or will expire; the possibility that our products will not generate sales that are commensurate with our expectations or that our cost of revenue or operating expenses may exceed our expectations; the mix of products and services sold in various geographies and the effect it has on gross margins; delays or decreases in capital spending in the cable, satellite, telco, broadcast and media industries; customer concentration and consolidation; the impact of general economic conditions on our sales and operations; our ability to develop new and enhanced products in a timely manner and market acceptance of our new or existing products; losses of one or more key customers; risks associated with our international operations; exchange rate fluctuations of the currencies in which we conduct business; risks associated with our CableOS ™ and VOS ™ product solutions; dependence on market acceptance of various types of broadband services, on the adoption of new broadband technologies and on broadband industry trends; inventory management; the lack of timely availability of parts or raw materials necessary to produce our products; the impact of increases in the prices of raw materials and oil; the effect of competition, on both revenue and gross margins; difficulties associated with rapid technological changes in our markets; risks associated with unpredictable sales cycles; our dependence on contract manufacturers and sole or limited source suppliers; and the effect on our business of natural disasters.

In one recent study, Choi and several colleagues wrote that smartphone addiction, like other impulse - control disorders, can «interfere with school or work; decrease real - life social interaction; decrease academic ability; and cause relationship problems.»

For in - house recruiters, the ability to share applicant information with the relevant hiring manager, as well as schedule interviews and gather feedback from those same hiring managers within one system can save time and decrease the number of days in the hiring cycle.

Additionally, our customers have the ability to cancel purchase orders in the event of any delays in production and may decrease future orders if delays are persistent.

If credit conditions worsen, and adversely affect the ability of customers to finance potential purchases at acceptable terms and interest rates, it could result in a decrease in sales of our products or delay any improvement in our sales.

Examples of these risks, uncertainties and other factors include, but are not limited to the impact of: adverse general economic and related factors, such as fluctuating or increasing levels of unemployment, underemployment and the volatility of fuel prices, declines in the securities and real estate markets, and perceptions of these conditions that decrease the level of disposable income of consumers or consumer confidence; adverse events impacting the security of travel, such as terrorist acts, armed conflict and threats thereof, acts of piracy, and other international events; the risks and increased costs associated with operating internationally; our expansion into and investments in new markets; breaches in data security or other disturbances to our information technology and other networks; the spread of epidemics and viral outbreaks; adverse incidents involving cruise ships; changes in fuel prices and / or other cruise operating costs; any impairment of our tradenames or goodwill; our hedging strategies; our inability to obtain adequate insurance coverage; our substantial indebtedness, including the ability to raise additional capital to fund our operations, and to generate the necessary amount of cash to service our existing debt; restrictions in the agreements governing our indebtedness that limit our flexibility in operating our business; the significant portion of our assets pledged as collateral under our existing debt agreements and the ability of our creditors to accelerate the repayment of our indebtedness; volatility and disruptions in the global credit and financial markets, which may adversely affect our ability to borrow and could increase our counterparty credit risks, including those under our credit facilities, derivatives, contingent obligations, insurance contracts and new ship progress payment guarantees; fluctuations in foreign currency exchange rates; overcapacity in key markets or globally; our inability to recruit or retain qualified personnel or the loss of key personnel; future changes relating to how external distribution channels sell and market our cruises; our reliance on third parties to provide hotel management services to certain ships and certain other services; delays in our shipbuilding program and ship repairs, maintenance and refurbishments; future increases in the price of, or major changes or reduction in, commercial airline services; seasonal variations in passenger fare rates and occupancy levels at different times of the year; our ability to keep pace with developments in technology; amendments to our collective bargaining agreements for crew members and other employee relation issues; the continued availability of attractive port destinations; pending or threatened litigation, investigations and enforcement actions; changes involving the tax and environmental regulatory regimes in which we operate; and other factors set forth under «Risk Factors» in our most recently filed Annual Report on Form 10 - K and subsequent filings by the Company with the Securities and Exchange Commission.

The chief ends in life are individual expression and success, with decreasing attention to the public good and even less ability to talk about the public good.

JED has been described as «an ecumenical sharing of abilities and expertise» and a partnership which makes «good, economic sense in these days of decreasing financial resources for the work of the church.»

The formation of the white blood cells, essential in fighting infection, is reduced in severe PEM, and the ability of white blood cells to engulf and consume bacteria is decreased.

Wheat and corn production already has been declining and the ability to catch fish in areas of the tropics is expected to decrease by 40 to 60 percent.

Diabetes is the decreased ability of your body to use glucose, especially in the form of simple, refined sugars.

The ability to provide consistent product, reliable supply and regular and transparent assurance that Australian food products are safe not only allows market access in these regions, but also enables the charging of premium prices and decreases the potential for non-tariff barriers.

The ability to move product from one workstation to the next in a safe, efficient, and sanitary way improves processing times, increases output, and often can result in decreased labor costs.

Being dehydrated can result in up to a 50 percent decrease in athletic ability.

Dehydration can result in up to a 50 percent decrease in ability.

There are strong speculations that the French playmaker could exit the team with decreasing confidence in his abilities by the coach Jose Mourinho but then the huge financial investment in him is a major hindrance.

When assessing potential targets, in any position, efficiency is king; with time a precious commodity and space on the pitch decreasing through the proliferation of highly effective pressing tactics, the ability to do things quickly and accurately becomes invaluable.

And as your baby grows and pushes up on your lungs, you'll notice a decreased ability to breathe in more air (and the oxygen it contains) when you exercise.

Children that don't get the nutrients their bodies need will often have decreased cognitive abilities and performance in the classroom.These children are also at a higher risk for disease, which means they will miss classes.

This orientation decreases the neck's ability to absorb shock, resulting in potential head trauma (e.g. concussion or worse) or spine fractures.

If we wish to impact and decrease infant mortality in our state, then the ability to provide human milk for all babies in need is crucial,» said Harley Ginsberg, MD, Section Head of Neonatology and Medical Director of Neonatal Intensive Care at Ochsner Baptist.

This decreases the number of calories that you take in each day and helps you lose weight, but it also affects your body's ability to absorb some important nutrients.

Furthermore, it is now clear that all kinds of crying (i.e. fussing, crying and inconsolable crying) is prolonged, that this prolongation occurs only in the first few months, and that inconsolable crying is almost unique to the first few months of life.3, 40 The «unpredictability» of the crying, and of the caregiver's ability or inability to soothe the infant is most likely due to the facts that (1) the infant cry in the first few months is a reflection of the organization of its behavioural states (crying, awake alert, sleeping), rather than an intentional «signal,» 14 (2) that behavioural state changes occur in «steps» rather than due to increases or decreases in arousal7, 41 and (3) infants are resistant to behavioural state change unless they are in a transitional phase in which they are «ready» to change state.7 Finally, there is now good evidence that the proportion of infants that have evidence of organic disease to explain their crying is less than 5 %.8, 42,43 In the absence of other compromise, infants with «colic» have as good an outcome as infants without «colic.&raquin the first few months, and that inconsolable crying is almost unique to the first few months of life.3, 40 The «unpredictability» of the crying, and of the caregiver's ability or inability to soothe the infant is most likely due to the facts that (1) the infant cry in the first few months is a reflection of the organization of its behavioural states (crying, awake alert, sleeping), rather than an intentional «signal,» 14 (2) that behavioural state changes occur in «steps» rather than due to increases or decreases in arousal7, 41 and (3) infants are resistant to behavioural state change unless they are in a transitional phase in which they are «ready» to change state.7 Finally, there is now good evidence that the proportion of infants that have evidence of organic disease to explain their crying is less than 5 %.8, 42,43 In the absence of other compromise, infants with «colic» have as good an outcome as infants without «colic.&raquin the first few months is a reflection of the organization of its behavioural states (crying, awake alert, sleeping), rather than an intentional «signal,» 14 (2) that behavioural state changes occur in «steps» rather than due to increases or decreases in arousal7, 41 and (3) infants are resistant to behavioural state change unless they are in a transitional phase in which they are «ready» to change state.7 Finally, there is now good evidence that the proportion of infants that have evidence of organic disease to explain their crying is less than 5 %.8, 42,43 In the absence of other compromise, infants with «colic» have as good an outcome as infants without «colic.&raquin «steps» rather than due to increases or decreases in arousal7, 41 and (3) infants are resistant to behavioural state change unless they are in a transitional phase in which they are «ready» to change state.7 Finally, there is now good evidence that the proportion of infants that have evidence of organic disease to explain their crying is less than 5 %.8, 42,43 In the absence of other compromise, infants with «colic» have as good an outcome as infants without «colic.&raquin arousal7, 41 and (3) infants are resistant to behavioural state change unless they are in a transitional phase in which they are «ready» to change state.7 Finally, there is now good evidence that the proportion of infants that have evidence of organic disease to explain their crying is less than 5 %.8, 42,43 In the absence of other compromise, infants with «colic» have as good an outcome as infants without «colic.&raquin a transitional phase in which they are «ready» to change state.7 Finally, there is now good evidence that the proportion of infants that have evidence of organic disease to explain their crying is less than 5 %.8, 42,43 In the absence of other compromise, infants with «colic» have as good an outcome as infants without «colic.&raquin which they are «ready» to change state.7 Finally, there is now good evidence that the proportion of infants that have evidence of organic disease to explain their crying is less than 5 %.8, 42,43 In the absence of other compromise, infants with «colic» have as good an outcome as infants without «colic.&raquIn the absence of other compromise, infants with «colic» have as good an outcome as infants without «colic.»

Lack of DHA in the body leads to serious consequences: inflammation of the skin, decreased learning ability, as well as disorders of concentration and memory, and these are some of the consequences.

Breast milk jaundice can be caused by substances in mother's milk that decrease the infant's liver's ability to deal with bilirubin.

As always, do follow up with your pediatrician if you become really concerned or you notice any significant changes / decreases in your baby's abilities.

Decreases in heart rate effect a decrease in blood pressure and promotion of the baby's ability to regulate their body temperature.

Pay attention to signs like increased interest in solid food (they'll probably try to steal if right off of your plate), ability to sleep through the night, sit up fully on their own, and a decreased interest in nursing, according to Baby Center.

You have the ability to decrease the stress and last - minute drama, if you respectfully and cordially confirm all the details with your children's mom well in advance.

«I see twisted harness straps all the time, which decreases their ability to hold your child securely in a crash,» says Dr. Hoffman.

To a large extent, state fiscal policies have caused great pressure on property taxes in needy cities, counties and school districts, including decisions: to reduce revenue sharing; to decrease the share of local school budgets covered by state aid, to divide the non-federal share of Medicaid costs without considering ability to pay, and to allocate STAR benefits... (read more)

In a press release, Pratt said the company's initial goals are to decrease the likelihood of car accidents, make driving accessible to everyone «regardless of ability,» and bring extra mobility to the home — «particularly for the support of seniors.»

RBS chief executive Stephen Hester told the Commons» Treasury committee reflected those of many in the City when he warned: «I believe that creating a ring - fence increases somewhat the systemic risk and decreases the ability of banks to withstand the risk and has significant costs.»

«If we increase wages, the ability to hire decreases, then it sets this whole city in another direction.»

Researchers from the University of Michigan, Wayne State University and Friedrich Miescher Institute for Biomedical Research in Switzerland found that suppressing the animal's ability to taste its food - regardless of how much it actually eats — can significantly increase or decrease its length of life and potentially promote healthy aging.

In frogs with the disease, the skin's ability to take up sodium and potassium ions from the water decreases by more than 50 per cent, Jamie Voyles of James Cook University in Townsville, Queensland, Australia, and his colleagues found (Science, DOI: 10.1126 / science.1176765In frogs with the disease, the skin's ability to take up sodium and potassium ions from the water decreases by more than 50 per cent, Jamie Voyles of James Cook University in Townsville, Queensland, Australia, and his colleagues found (Science, DOI: 10.1126 / science.1176765in Townsville, Queensland, Australia, and his colleagues found (Science, DOI: 10.1126 / science.1176765).

Huntington's disease is a brain disorder characterized by the emergence of decreased motor, cognitive, and psychiatric abilities, most commonly appearing in the mid-30s and 40s.

«We know that exposure to smoking cues such as visual depictions of cigarettes, ashtrays, matches, lighters, and smoke heightens smokers» urge to smoke a cigarette, and decreases former smokers» confidence in their ability to refrain from smoking a cigarette,» said Dr. Maloney.

This chimera, created by a team at the Georgia Cancer Center, has the ability to simultaneously decrease the expression of three growth factors that are over-expressed in some cancers.

However, the reduction in the numbers of stomatal pores decreases the ability of plants to cool their leaves during a heat wave via water evaporation.

In regions that had undergone improvements in living conditions and expansion of gender - equal educational opportunities, women displayed superior memory to men, men's advantage in mathematical abilities decreased, and equivalent abilities in category fluency were observeIn regions that had undergone improvements in living conditions and expansion of gender - equal educational opportunities, women displayed superior memory to men, men's advantage in mathematical abilities decreased, and equivalent abilities in category fluency were observein living conditions and expansion of gender - equal educational opportunities, women displayed superior memory to men, men's advantage in mathematical abilities decreased, and equivalent abilities in category fluency were observein mathematical abilities decreased, and equivalent abilities in category fluency were observein category fluency were observed.

The findings could have an impact on the tests and measurements that physicians rely on to diagnose and treat two heart conditions: hypertrophic cardiomyopathy, in which the heart muscle becomes abnormally thick, and non-ischemic dilated cardiomyopathy, in which the heart's ability to pump blood decreases as the organ's main pumping chamber, the left ventricle, is enlarged and its muscle thinned.

Therefore, screening could result in over-treatment and consequently in decreased quality of life and ability to function in older breast cancer patients, without lowering the incidence of advanced stage breast cancer or deaths from the disease,» he said.