Generation of animals deficient
in desmin (structuring protein of muscle fibers involved in human muscular dystrophies) using TALE nucleases.
Not exact matches
As shown
in Figure 4, all three germ layers developed
in our cultures as shown by alphafetoprotein (AFP) for endoderm (Figure 4B), smooth muscle actin (SMA) and
desmin for mesoderm (Figure 4D, E), glial fibrillary acid protein (GFAP) and SMI31 for ectoderm (Figure 4G, H).
(A) iPS cells can form embryoid bodies (EB) and can differentiate
in vitro to endoderm shown by alpha fetoprotein (AFP)(B), mesoderm shown by smooth muscle actin (SMA) and
desmin (D, E), and ectoderm shown by GFAP and SMI31 staining (G, H).