Not exact matches
Molecular characterization
of the
cells that undergo
cell fate transition upon oncogenic Pik3ca expression demonstrated a profound oncogene - induced reprogramming
of these newly formed
cells and identified gene expression signatures, characteristic
of the
different cell fate switches, which was predictive
of the
cancer cell of origin, tumour
type and clinical outcomes
in women with breast
cancers.
In their latest study, they tested compounds against
cells from nine
different types of human
cancer, including common
types affecting blood, colon, breast, prostate, ovaries, kidneys, and lungs.
«
Different types of cancer cells with different strengths and weaknesses are both present in the tumor at the same time and can work together to spread faster and more eff
Different types of cancer cells with
different strengths and weaknesses are both present in the tumor at the same time and can work together to spread faster and more eff
different strengths and weaknesses are both present
in the tumor at the same time and can work together to spread faster and more efficiently.
The study published
in Cancer Cell shows that exosomes from tumor cells of breast cancer (and other tumor types such as ovarian and endometrial) are different in size and composition than those of healthy
Cancer Cell shows that exosomes from tumor
cells of breast
cancer (and other tumor types such as ovarian and endometrial) are different in size and composition than those of healthy
cancer (and other tumor
types such as ovarian and endometrial) are
different in size and composition than those
of healthy
cells.
PTEN prevents tumor
cells from growing uncontrollably, and mutations
in the gene encoding this protein are commonly found
in many
different types of cancer.
For each patient, the suitable combination treatment could then be designed, which,
in the first step, would turn the variety
of different tumor
cells into a mass
of cancer cells of the same
type.
Backman has been studying
cell abnormalities at the nanoscale
in many
different types of cancers, using an optical technique he pioneered called partial wave spectroscopic (PWS) microscopy.
The team used five
types of antibiotics — including one used to treat acne (doxycycline)-- on
cell lines
of eight
different types of tumour and found that four
of them eradicated the
cancer stem
cells in every test.
If the finding that resident memory T
cells are the most potent mediators
of immunity holds up
in different types of cancer, which I think it will, you could take a biopsy
of the lung or the pancreas, for example, to see if there are resident T
cells there.
They found that the number
of copies
of lncRNA genes on a chromosome consistently change
in 12
different cancer types and lncRNA genes are widely expressed
in cancer cells.
«We've seen this
in six
different types of human
cancer cell lines
in the lab,» Choudhury said.
• Given the fact that normal
cells possess wild -
type p53 function, FL118 - induced p53 activation might explain the favorable toxicology profile
of FL118: highly toxic to
cancer cells but not so
in healthy animal
cells, and these
different consequences might be mediated through p53 activation.
Surprisingly, they found that although the patterns
of gene expression — as shown by the RNA sequencing — differed between the hepatocellular carcinomas and the liver
cancers with biliary phenotype and depended on the histological
type, the overall pattern
of mutations
in the
cells was actually similar between the tumors —
of either
type — that had emerged
in patients who had had infections with either hepatitis C or B, and were
different in patients without such infections.
«Although right now we are focusing on developing a
cancer vaccine,
in the future we could be able to manipulate which
type of dendritic
cells or other
types of immune
cells are recruited to the 3D scaffold by using
different kinds
of cytokines released from the MSRs,» said co-lead author Aileen Li, a graduate student pursuing her Ph.D.
in bioengineering at Harvard SEAS.
They found that silencing the TOR signalling pathway — activated
in many
different types of cancer — increased ER stress
in the
cells.
Christian Seiser says: «Our results highlight that it is crucial to understand the individual role the various HDAC variants
in different cell types and hence
different types of cancer, before HDAC inhibitors can be used safely as therapeutics.»
The notable differences
in fluorescence intensity observed between normal
cells and
cancer cells, as well as
different cancer types, provide important points
of differentiation between
different cell types and make these probes promising tools for
cancer detection and diagnostics.
If these preclinical studies are successful, the researchers plan to further develop their CAR T
cell therapy and test its safety and efficacy for
different types of metastatic
cancer in upcoming clinical trials.
«Our work outlines the genetic similarities
of the tissue and
cells in different types of tumors and shows the strong relationships mice can have to other human
cancers too.»
They analysed about a million
different cell mutations
in more than 7,000 tumours from the
Cancer Genome Atlas covering 24 types of c
Cancer Genome Atlas covering 24
types of cancercancer.
Different types of tumors show a preference for specific organs and tissues; circulating breast
cancer cells, for example, are likely to take root
in bones, lungs, and the brain.
Dr. David Gilley's laboratory at the Indiana University School
of Medicine
in Indianapolis and Dr. Connie Eaves» laboratory at the BC
Cancer Agency's Terry Fox Laboratory
in Vancouver, Canada, collaborated to determine how telomeres are regulated
in different types of normal breast
cells.
The research highlights the importance
of investigating
different cell types in normal human tissues to understand the cellular origin
of cancer and the factors that may contribute to its development.
A research team, led by Chao Cheng, Ph.D., Assistant Professor
in the Department
of Genetics at The Geisel School
of Medicine at Dartmouth, used gene expression data from breast
cancer patients to computationally infer the presence
of different types of immune
cells.
Studying
cancer with single -
cell technology will allow us to unlock the interactions between
different types of cells in tumors — and monitor how these interactions change over time, affecting patients» outcomes.
Expression
of Snail represses expression
of E-cadherin and induces EMT
in different cell types, including breast
cancer cells [36, 37].
• Detect Zika virus
in blood and urine samples within hours and distinguish between its African and American strains • Distinguish between Zika and dengue • Discriminate
different types of bacteria, like E. coli • Detect
cancer cell mutations • Detect antibiotic resistance genes • Read human genetic information from saliva sample
Their strategy, described
in the Jan. 4, 2009 issue
of the journal Nature Medicine, could not only prove a very useful method to faithfully reproduce
different types of tumors but also to elucidate the nature
of elusive
cancer stem
cells.
-- discovery awarded international science prize Researcher Allison Cleary has, for the first time, demonstrated that
different types of tumor
cells cooperate
in the development and growth
of breast
cancer.
While many
different types of cancer can occur
in the head and neck, squamous
cell carcinoma
in the most common
cancer of the head and neck.
Researcher Allison Cleary has, for the first time, demonstrated that
different types of tumor
cells cooperate
in the development and growth
of breast
cancer.
Although
cancer stem
cells have been identified
in many
different types of cancer, it is becoming increasingly clear that the properties
of these
cells may vary greatly among the
different tumor
types.
Similar to primary keratinocytes, long - term — cultured squamous
cell carcinoma (30) and many other epithelial
cancer cells (30, 31) can also form
different types of clones
in culture.
These results reveal that prostate
cancer cells are heterogeneous
in establishing
different types of clones.
It means that
cancers are not the same — between
types of cancers, between
cancers in different individuals, even between
cancer cells within the same person.
For example, studies
of cell signaling pathways
in normal
cells and
cancer cells have contributed greatly to our knowledge about the disease, revealing molecular alterations that are shared among
different types of cancer and pointing to possible strategies for treatment.
Non-Hodgkin lymphoma — sometimes also called non-Hodgkin's lymphoma or just NHL — covers a number
of different cancers that start
in a specific
type of white blood
cells called lymphocytes.
While cancerous
cells have a variety
of different causes, excessive alcoholic intake can increase the risk
of various
types of cancers, including neck, liver, breast, and colorectal, and may play a role
in the development
of many other
types of cancers, though the link has yet to be proven.
And, anthocyanins also trigger apoptosis — or
cell suicide —
in several
different types of cancer cells.
Interleukin - 8 (IL - 8), a well - known tumor - growth promoting inflammatory cytokine104 is «substantially increased»
in a number
of different types of cancer cells.105 «We found for the first time that caprylic acid and MCT suppress IL - 8 secretion by Caco - 2
cells [colon
cancer cells],» reported Japanese researchers
in 2002.106
It's been shown to be anticancer, fights
cancer in over 60
different cancer cell lines, meaning 60
different types of cancer.
In a study published this year in Current Drug Targets, a combination of tocotrienols and quercetin induced senescence and promoted apoptosis in many different types of cancer cells, while delaying senescence in healthy cells and rejuvenating formerly healthy senescent cell
In a study published this year
in Current Drug Targets, a combination of tocotrienols and quercetin induced senescence and promoted apoptosis in many different types of cancer cells, while delaying senescence in healthy cells and rejuvenating formerly healthy senescent cell
in Current Drug Targets, a combination
of tocotrienols and quercetin induced senescence and promoted apoptosis
in many different types of cancer cells, while delaying senescence in healthy cells and rejuvenating formerly healthy senescent cell
in many
different types of cancer cells, while delaying senescence
in healthy cells and rejuvenating formerly healthy senescent cell
in healthy
cells and rejuvenating formerly healthy senescent
cells.
A lab - based study showed that myrrh actually inhibited the growth
in eight
different types of cancer cells.
Curcumin inhibits the growth and spread
of different types of cancer cells,
in particular leukemia, hepatic, colorectal, pancreatic, gastric, prostate, breast, and oral
cancers.
But because metformin may stem
cancer through several
different channels — by lowering insulin, directly slowing tumor growth, or promoting suicide by
cancer cells — it could potentially prove useful
in many
types of cancer.
Cell - based vaccine strategies that stimulate anti-tumor immunity have shown promise
in the treatment
of many
different cancer types including non-Hodgkin's lymphoma (NHL)
in humans.