The publication of the latest Canine genome build and annotation, CanFam3.1 provides an opportunity to enhance our understanding of gene regulation across tissues
in the dog model system.
«Gene therapy leads to long - term benefits
in dog model of devastating childhood disease.»
Not exact matches
In an effort to entice fashion - forward
dog owners into buying, Roni lines up canine catalog
models for a photo shoot.
Paul's text has helped me find
in this memory a paradigm, a warm, rough
model for the ministry: the ministry is like the role of the adolescent boy playing midwife to his beloved
dog.
He did not set up office hours on the front porch (the clinic
model) and send out a general announcement to all
dogs in the neighborhood that he was there if they cared to come.
Graduation «Don Shula is «An athlete and role «
In this home of Day Tribute the embodiment
model... you played the cheese of winning» Bobby Riggs and won» steak, you're our hot
dog»
Yes,
dogs sometimes need CPR too, and veterinary schools have been using the fake Fido as a practice
model since it was invented
in 1983 by Cornell veterinary professor Dr. Charles E. Short.
Supporters of Clark argue that she's been a
model prisoner, earning two college degrees and taking part
in programs that trained service
dogs and tutored other inmates.
This is advantageous, since
dogs provide new
models to investigate the disease mechanisms and to plan new therapies such as gene therapy, successfully applied to blindness
in dogs and human previously,» explains Lohi.
Dr Luis Pedro Coelho, commented: «These findings suggest that
dogs could be a better
model for nutrition studies than pigs or mice and we could potentially use data from
dogs to study the impact of diet on gut microbiota
in humans, and humans could be a good
model to study the nutrition of
dogs.
«Data from this study serves as rationale to now include
dogs with spontaneous cancers
in the advancement and optimization of PMed for human patients,» according to the study, Prospective molecular profiling of canine cancers provides a clinically relevant comparative
model for evaluating personalized medicine (PMed) trials.
And the trouble with extrapolating so much from mouse studies is that «nobody has actually shown over the long term how long these quote un-quote improvements persist, and we don't know whether it's broadly improving aspects of aging or it's specific to certain tissues,» said Matt Kaeberlein, a biologist who studies aging
in dogs and other animal
models at the University of Washington.
Robot
dog Aibo was launched
in 1999 and after several different
models was discontinued
in 2006.
To better understand a heart
in extremis, two medical researchers have made a three - dimensional
model of the electrical activity
in a
dog's heart.
The researchers told MIT Technology Review that their next step is engineering
dogs with humanlike illnesses for use as
models in medical research.
Dogs» and other mammals» responses to and offerings of displays of affection, which are so unlike an autistic person's relationship to other people, completely undermine the
model proposed
in the article for interspecies understanding.
«There's a lot of literature that points to chondrodystrophy
in dogs as an exciting animal
model for degenerative disc disease
in people,» said Bannasch, who also holds the Maxine Adler Endowed Chair
in Genetics.
«The
dog has a retina very similar to ours, much more so than mice, so when you want to bring a visual therapy to the clinic, you want to first show that it works
in a large animal
model of the disease,» said lead researcher Ehud Isacoff, professor of molecular and cell biology at UC Berkeley.
«The
dog is an invaluable
model for exploring hereditary copper - storage diseases, and observations made
in this study will benefit both canine and human patient populations.»
Using a genome - wide approach
in a new
dog model for copper toxicosis, a team of researchers led by Hille Fieten have now revealed that mutations
in a copper transporter gene, ATP7A, can ameliorate symptoms of the disease.
So we would never make the argument that
dogs in general are a better
model for the human mind — it's really just this special set of social skills.»
So geneticists have been focusing on the
dog as a possible
model for gene searches because this lack of sequence variation may help them circumvent a frequent problem with studies
in humans.
So pet
dogs might not be a suitable
model for colon cancer
in humans.»
The alternative
model is that mutations of large phenotypic effect underlie most of these traits
in dogs and that the same variants have been transferred to a wide diversity of
dog breeds leading to phenotypic diversity from a narrow genetic base [5], [8], [12].
But are mice and rats good
models for these complex diseases, can depression
in dogs really equate with depression
in people, and how much does that matter?
We sequenced exons and regulatory elements for 608 genes implicated
in OCD
in humans and two animal
models, mouse and
dog.
Guilak's
models are now being tested
in hound
dogs, which also develop hip issues.
One of her special interests is the field of veterinary comparative oncology: the study of naturally occurring cancers
in pet
dogs provides a suitable
model for the advancement of the understanding, diagnosis and management of cancer
in humans.
The research team had already shown that the technique worked
in mice but needed a more accurate
model of human diabetes and so used
dogs.
Visual signaling from biologically - inspired robots has been used to investigate the behavior of birds [27]--[31],
dogs [32], lizards [33], fish [22], [34]--[42], and rats [43]; salient chemical cues have been implemented on a miniature mobile robot to investigate social behavior of cockroaches [44]; audio feedback has been integrated
in a
model of a robotic squirrel to influence squirrels» behavior [45]; pulsing air currents created by robotic honeybees have been used to investigate honeybees» dance [46]; and hydrodynamic cues from a swimming robotic fish have been considered
in [20] to modulate fish behavior
in a water tunnel.
However, population viability
models in African wild
dogs suggest that diseases causing high adult mortality can pose a significant extinction threat [19].
Their analytical
model can also be applied to
dogs and horses — indeed, to any species that show structured breeding
in their populations instead of random gene flow.
In January, model and actress Emily Ratajkowski was spotted in New York walking a dog — and wearing nothing but lingerie and black moto boot
In January,
model and actress Emily Ratajkowski was spotted
in New York walking a dog — and wearing nothing but lingerie and black moto boot
in New York walking a
dog — and wearing nothing but lingerie and black moto boots.
Five vintage cars and their chauffeurs, alongside seven pairs of pedigree
dogs were gathered together with the
models in Brooklyn to stage this striking story of an iconic degree.
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Comedic force of nature Eddie Pepitone delivers a darkly funny, rage - fueled performance
in Brooklyn, where he discusses the perils of being a male
model, speaking to his
dog like his therapist, and the death of the American Dream.
From dealing with cats and
dogs in his white lab coat during the day to
modeling with bikini girls at night, this is the true story about Russell Mitchell and how one of his legendary motorcycles comes to life.
Modeled after Toshiro Mifune's towering performance
in Akira Kurosawa's «High and Low» (the first of the film's many nods to Japan's most famous director), the villainous bureaucrat suggests relocating every single one of the
dogs in Uni Prefecture to a place called Trash Island, starting with his own Short - Haired Oceanic Speckle - Eared Sport Hound, Spots.
Once
in the backwoods, Melanie: reunites with sour Ma (Mary Kay Place) and dour Pa (Fred Ward), both actors
modeling their characters on Grant Wood's necessarily two - dimensional painting «American Gothic»; «outs» poor Bobby Ray (Ethan Embry)--
in the real world, they'd probably have been hung from the same pole flying the Confederate Flag outside the local watering hole; and delivers the most embarrassing monologue since Phoebe Cates's
in Gremlins to, of all things, a license plate marking the burial spot of a «coon
dog» named after legendary Crimson Tide coach Paul «Bear» Bryant.
But at 17 she got her big break, when she was spotted by a
modelling scout as she walked her
dog outside Harrods, and she is now
in the running for the EE Bafta Rising Star Award.
The character of Spot is more of a
dog than a human
in the function of the story, so it just made sense to
model his movements off of creatures of that kind.
Wenn
Model Yolande Ngom has accused Miley Cyrus of perjury
in a
dog attack lawsuit filed against the pop star's half - sister Brandi.
Watching it, I was reminded strongly of Krzysztof Kieslowski's magnificent Red,
in which the relationship between a young
model and her own emotionally insecure boyfriend echoes a story from the distant past of a reclusive judge (played, as it happens, by Amour star Jean - Louis Trintignant) whom the
model meets when she runs over his
dog.
The
model and photographer, 49, on her fear of death, why she'd choose to photograph Marilyn Monroe and being
in love with her
dog
In response to outbreaks of snout fever and canine flu,
dog - hating Mayor Kobayashi (
modelled on the great Japanese screen actor Toshiro Mifune and voiced by co-writer Kunichi Nomura) banishes the mutts of Megasaki City to Trash Island, starting with his own household's loyal Spots.
Additionally, the puppetry is the film's crowning technical accomplishment, with each of the adorable
dog models conveying a physical heft, texture and painstakingly achieved articulation that is reminiscent of the artistry
in Aardman's claymation output and the Rankin / Bass holiday specials.
Parents who play an instrument can
model good practice behavior by fitting
in some practice time themselves, even during the
dog days of summer.
There's a similar progression
in the electronically limited top speeds: even the base
model is good for 161 mph, the S for 171 mph, and the top
dog for 186 mph.