Dr. Ghavami joined PsychoGenics in 2007 and directs molecular biology and electrophysiology groups and has been extensively involved
in drug discovery research.
Deuterium - and tritium - labeled pharmaceutical compounds are pivotal diagnostic tools
in drug discovery research, providing vital information about the biological fate of drugs and drug metabolites.
Experts say it could also help to boost supplies of cells for use
in drug discovery research and could eventually aid production of cells for use as therapies.
Not exact matches
Pharmanet's
drug discovery program was recently expanded to include additional
in vitro programs, which are to be undertaken by independent scientists at government - supported medical
research facilities
in Perth.
In January 2017, SiteOne announced the closing of a
research and development agreement with Amgen, a collaboration focused on combining SiteOne's experienced
drug discovery team and portfolio of novel Naᵥ1.7 inhibitors with Amgen's neuroscience capabilities.
«Her breadth of experience
in biomedical
research and development can benefit Exelixis greatly as the company recommits its resources to
drug discovery and bolstering its pipeline following the successful ongoing commercialization of its lead medicine, CABOMETYX.»
An original co-founder of MaRS, U of T has chosen the site for its renowned
research teams working
in drug discovery, regenerative medicine, infectious diseases and advanced computing.
As an investment, a
drug that is
in the
discovery or pre-clinical stage is a very risky proposition, with less than a 1 % chance of getting to market (according to an industry report published
in 2003 by the Pharmaceutical
Research and Manufacturers of America).
Looking at sixty - seven recent
drug discovery projects based on preclinical cancer biology
research, they found that
in more than 75 percent of cases the published data did not match up with their
in - house attempts to replicate.
In listening to our terminally ill patients, we were always impressed that even the most accepting, the most realistic patients left the possibility open for some cure, for the discovery of a new drug or the «last minute success in a research project.&raqu
In listening to our terminally ill patients, we were always impressed that even the most accepting, the most realistic patients left the possibility open for some cure, for the
discovery of a new
drug or the «last minute success
in a research project.&raqu
in a
research project.»
Founded
in 1998 by Leonard A. and Ronald S. Lauder, the ADDF provides critical seed funding to leading scientists conducting breakthrough
drug discovery and clinical
research.
New York State was planning to invest
in a new facility
in Buffalo for a
drug discovery company, Albany Molecular
Research Inc., and the medical campus was being invited to partner.
The latest
research in Science Signaling, covering cell signaling and regulation, synthetic biology, and
drug discovery.
Although the pharmaceutical industry, like the rest of the business world, has suffered a slowdown, the market
research company Frost and Sullivan still expects spending on
drug discovery to expand from US$ 19.6 billion
in 2002 to US$ 25.6 billion by 2006, an annual growth rate of about 6 %.
Of approximately 300 staff at the Center for Therapeutic
Research, only nine postdocs and students are conducting basic research; the rest work in drug discovery and deve
Research, only nine postdocs and students are conducting basic
research; the rest work in drug discovery and deve
research; the rest work
in drug discovery and development.
Making the Leap: When, How, and Why a Career
in Drug Discovery May Be Right for You Matthew Bell who heads of discovery research for Wyeth Pharmaceuticals tells when, how, and why a career in drug discovery may be right for
Drug Discovery May Be Right for You Matthew Bell who heads of
discovery research for Wyeth Pharmaceuticals tells when, how, and why a career
in drug discovery may be right for
drug discovery may be right for you.
Richard Hargreaves, executive director of imaging at Merck
Research Laboratories, says, «Nuclear imaging using radiotracers gives the opportunity to put your arms around proof - of - concept very early
in a
drug discovery and development program by focusing the selection of doses to study on those proven to deliver enough
drug to the target therapeutic sites.»
«
In any CNS
drug discovery program,» Hargreaves says, «occupancy studies form a very early part of
research.
During one - third of the year, the students will learn about the cutting - edge developments
in the life sciences with the greatest entrepreneurial potential — from bioinformatics to neuroscience, epidemiology,
drug discovery, and stem cell
research.
The journal provides cutting - edge
research including results from animal models that are likely to apply to patients, studies
in human tissue that provide new information about therapies or disease, and innovative reports of
drug discovery and development.
Promega, headquartered
in Madison, Wisconsin, has nearly a thousand employees worldwide and manufactures over two thousand products, consisting of kits and reagents as well as integrated solutions for life science
research and
drug discovery, genetic identity, and clinical diagnostics.
Lowe, a medical chemist by profession, provides daily commentary on
drug discoveries, the pharmaceutical industry, and relevant
research and news, especially
in chemistry.
«With the availability of more and more data analytics
in health care, it's the right time to use data to direct the investments of
drug discovery and biomedical
research for the common good,» said the study's first author, Lixia Yao, PhD, assistant professor at the University of North Carolina at Charlotte.
The Canadian
drug discovery industry is still small, especially
in comparison to the United States, owing to the lack of big pharmaceutical companies conducting
research and development
in this country.
Kotra is content to remain
in academic
research, despite the somewhat limited funding for chemistry studies with a
drug discovery focus.
Scientists are taking medical imaging
research and
drug discovery to a new level by developing a molecular imaging system that combines several advanced technologies for all -
in - one imaging of both tissue models and live subjects, say presenters at the 2015 Annual Meeting of the Society of Nuclear Medicine and Molecular Imaging (SNMMI).
Working on the premise that scientific
research is the foundation of any technology industry, Hancock and others at UBC are writing a business proposal for an integrative centre for
drug research, with an objective of developing intellectual property
in drug discovery, providing training for
drug discovery researchers, and developing new technologies.
«These results enable future studies
in Alzheimer's and other disease models and highlight the importance of basic
research which precedes
drug -
discovery,» says Jaan - Olle Andressoo.
He believes that a great deal of
drug discovery research, and hence informal training
in the area, is performed at academic institutions located
in Canada's bioscience clusters, and their spin - off companies.
The
discovery involved ORNL's Spallation Neutron Source, which provides the most intense pulsed neutron beams
in the world for scientific
research and industrial development, and ORNL's Titan supercomputer, the nation's most powerful for open science — a one - two punch for illuminating the physical properties of potential
drugs that inform new design principles for safer, improved delivery platforms.
«While we celebrate the «a ha» moment of scientific
discovery and invention, such moments are only the point of initiation for the basic
research required to develop new
drugs,» said Dr. Laura McNamee, the lead author of the paper and a
research associate
in Bentley's Center for Integration of Science and Industry.
«This opens up entirely new opportunities
in pharmaceutical
research and may lead to the
discovery of new
drugs,» says Yitzhak Apeloig, who specializes
in organic chemistry at the Technion Israel Institute of Technology
in Haifa.
Hooker and Van de Bittner note, however, that the tool also has tremendous potential for
research applications, particularly for
drug discovery in smell - loss therapy and
in understanding the relationships between olfactory neuron health and brain health more generally.
An essential new way to move
discoveries forward has emerged
in the form of multi-stakeholder collaborations involving three or more different types of organizations, such as
drug companies, government regulators and patient groups, write Magdalini Papadaki, a
research associate, and Gigi Hirsch, a physician - entrepreneur and executive director of the MIT Center for Biomedical Innovation.
Some basic
research findings are being translated into new treatments, and with the
discovery of induced pluripotent stem cells
in 2006, the field has seen a step - change
in biological understanding that will affect the way new
drugs are identified and tested and, potentially, the way cells can be generated
in the lab.
I've almost completed this study, so it's time to apply the results
in Organon's
drug discovery research.
New
research published
in Nature Methods will dramatically improve how scientists «see inside» molecular structures
in solution, allowing for much more precise ways to image data
in various fields, from astronomy to
drug discovery.
Research like this, that's made publically available, will help speed up crucial advances
in drug discovery to save more lives from cancer.»
One of the most exciting recent advances
in clinical cancer
research was the
discovery that this subgroup of patients respond — sometimes dramatically — to a new class of
drugs targeting the MAPK pathway through which BRAF signals.
Research continues to apply this fundamental
discovery to the development of innovative
drugs that could inhibit the X protein» highlights Dr. Simon Fletcher, from Gilead Sciences, Inc., whose team provided the
in vivo verification of the
discoveries made by the University of Geneva microbiologists.
The
discovery, made
in research laboratories at the University of Michigan Medical School and the U.S. Food and
Drug Administration, is published
in the online journal PLoS Pathogens.
For the study, Ho and Kosik, leading experts
in Alzheimer's
research, compiled a list of 64 conceivable approaches to
drug discovery, addressing a range of biological mechanisms that may be involved
in the disease.
Draper's human organ system should be able to identify effective
drugs and ineffective ones early
in the
drug discovery process, allowing developers to refocus resources on the strong candidates earlier and end unproductive
research earlier, minimizing costs, Borenstein said.
The experimental
research, conducted by Griffith University's Centre for Quantum Dynamics, aims to help
in the design of new molecules for materials science or
drug discovery.
This has resulted
in industry laboratories dedicated to
drug discovery or human genome
research.
We had been looking for a senior scientist with experience
in high throughput screening (HTS) assay development for a large
drug discovery research program.
Systems biology provides better methods of
drug discovery:
research teams can measure changes
in genetic activity, protein levels and cellular behavior of the immune system
in response to a potential vaccine.
Overall, the upcoming involvement of academia
in the
drug discovery process will provide graduate students and postdocs the opportunity to gain experience and skills which are important for pharmaceutical and biotech companies whilst still engaging
in hypothesis - driven academic
research.
Their
discovery might ultimately lead to an alternative treatment for jaundice, such as a new
drug or supplement, says Daniel Kim, a
research technician
in Guelph's Department of Biomedical Sciences.
An example of the academic
drug discovery process and one that my own
research has focused on is the
discovery of CFTR chloride channel inhibitors and the role of CFTR
in intestinal fluid secretion.