Sentences with phrase «in drug side»

«In the future, if it is confirmed that similar mechanisms exist in humans, we expect our research to lead to optimal dosing and a reduction in drug side effects.»

Not exact matches

These risks and uncertainties include, among others: the unfavorable outcome of litigation, including so - called «Paragraph IV» litigation and other patent litigation, related to any of our products or products using our proprietary technologies, which may lead to competition from generic drug manufacturers; data from clinical trials may be interpreted by the FDA in different ways than we interpret it; the FDA may not agree with our regulatory approval strategies or components of our filings for our products, including our clinical trial designs, conduct and methodologies and, for ALKS 5461, evidence of efficacy and adequacy of bridging to buprenorphine; clinical development activities may not be completed on time or at all; the results of our clinical development activities may not be positive, or predictive of real - world results or of results in subsequent clinical trials; regulatory submissions may not occur or be submitted in a timely manner; the company and its licensees may not be able to continue to successfully commercialize their products; there may be a reduction in payment rate or reimbursement for the company's products or an increase in the company's financial obligations to governmental payers; the FDA or regulatory authorities outside the U.S. may make adverse decisions regarding the company's products; the company's products may prove difficult to manufacture, be precluded from commercialization by the proprietary rights of third parties, or have unintended side effects, adverse reactions or incidents of misuse; and those risks and uncertainties described under the heading «Risk Factors» in the company's most recent Annual Report on Form 10 - K and in subsequent filings made by the company with the U.S. Securities and Exchange Commission («SEC»), which are available on the SEC's website at www.sec.gov.

Canada's generic drug king found himself on the wrong side of several shaking fingers in the past year.

That defensive position came under attack in 2015 as political rhetoric from both sides zeroed in on perceived unfair drug pricing.

Companies like U.S. biotech giant Gilead and the U.K.'s GlaxoSmithKline (the majority stakeholder in global HIV partnership ViiV Healthcare) have developed drugs that drastically lower the chance of HIV infection — or which simply lower the number of drugs you have to take to treat it, consequently curbing the risk of toxic side effects while simplifying medical regimens.

The experimental drug, according to reports, sharply reduced the cell - killing protein in the subjects» nervous systems and apparently had no major side effects.

In addition to partnering with Celgene (celg) to better track negative drug side effects, IBM (ibm) is applying its cognitive computing AI technology to recommend cancer treatment in rural areas in the U.S., India, and China, where there is a dearth of oncologists, said Deborah DiSanzo, general manager for IBM Watson HealtIn addition to partnering with Celgene (celg) to better track negative drug side effects, IBM (ibm) is applying its cognitive computing AI technology to recommend cancer treatment in rural areas in the U.S., India, and China, where there is a dearth of oncologists, said Deborah DiSanzo, general manager for IBM Watson Healtin rural areas in the U.S., India, and China, where there is a dearth of oncologists, said Deborah DiSanzo, general manager for IBM Watson Healtin the U.S., India, and China, where there is a dearth of oncologists, said Deborah DiSanzo, general manager for IBM Watson Health.

Agios Pharmaceuticals shares plunged more than 18 percent after the company discontinued development of an experimental drug for rare blood disorder due to side effects seen in a study.

The side effect was first observed earlier this month at the American Society of Hematology conference, where CEODavid Schenkein spoke with CNBC about the safety of one of the molecules in its drug, which was meant to treat pyruvate kinase deficiency, a rare, genetic anemia.

She said that employers» increased use of high - deductible plans, one of the side - effects of the law, has resulted in patients paying more out of pocket for the drug, and that's «where you're seeing a lot of noise around EpiPen.»

The flip side of that, though, is that an increase in demand for prescriptions will only intensify government efforts to keep drug costs down.

Our Government is also committed to ensuring that drug labels are written in plain language, and that the potential side effects of medication are accurately indicated.

These healthcare brands will have the effect of soothing out the inevitable fluctuations that occur on the pharmaceutical side, though right now, Glaxo's portfolio is boasting robust growth from small - scale HIV drugs Triumeq and Trivicay (which, as the CEO noted in the last annual report, sport year - over-year sales growth of 41 % and 43 %, respectively).

To combat the activities of Mexican, Central American, and South American transnational criminal organizations — including illicit finance and money laundering activities and the flow of illegal drugs — the FBI works side - by - side with its numerous domestic and international partners to infiltrate, disrupt, and dismantle these groups by targeting their leadership and using sensitive investigative and intelligence techniques in long - term, proactive investigations.

But in 2010 and 2013, the F.D.A. rejected the drug for that use, saying the side effects, including nausea and dizziness, outweighed the benefits.

Luxury condo conversion of drug rehab center in NYC's Upper West Side priced for $ 61 million sellout

If there is a competitive drug market, with limited advantage offered by the new drug in terms of increased effectiveness or reduced side effects, the drug will probably not win substantial market share in its product category.

ALKS 3831 is a treatment for schizophrenia that avoids the side effects of weight gain and metabolic problems that the incumbent drug has, and a phase 3 trial for it should read out in the fall of 2018.

Just about every illegal drug can be used in a medicinal way, often with less danger from side effects or addiction than legal drugs.

It tells the story of «the guinea pigs»» the people most likely to be research subjects in Phase I trials, which test the safety of a drug under development by giving it to healthy subjects and examining any side effects they experience.

It raves about how wonderful the drug can make you feel in the short term but then lists some major side effects: premature relational difficulty, divorce, shallow relationships.

When I meet the drug addicts in downtown east side, both their character and the conditions they're stuck in need to change.

Even if we can not know the answer to all of society's ills, even if we can not pretend to know how to solve the problems of crime and drugs and inflation and poverty, we can still proclaim that it is obviously and unquestionably a moral wrong to maintain a penal system based on vengeance instead of rehabilitation; to allow human rights violations to go unchallenged (on either side of the iron curtain); to waste vast quantities of food and resources while others are malnourished and sick and poor; or to allow so many children in our own midst to go through childhood unwanted and unloved and even abused.

The conclusion: given relatively unlimited availability, heroin users will voluntarily stabilize or reduce their dosage and some will even choose abstinence; long - addicted users can lead relatively normal, stable lives if provided legal access to their drug of choice, and with few side effects; and ordinary citizens (in Switzerland at least) will support such initiatives.

«In upcoming episodes we will be showing the very negative side of drug taking as Billy's life starts to fall apart.»

One animal study even found it worked as well as the anti-inflammatory drug indomethacin in treating arthritis, but without the side effects.8

When inflammation strikes, we are conditioned into reaching for a quick fix in the way of pharmaceutical or prescribed drugs such as aspirin and ibuprofen, temporary panacea's that come with their own adverse side effects and with long term use have the potential to create a host of health problems independently.

After suffering from the terrible side effects of steroids, antibiotics, and immunosuppressant drug therapy, I decided to do some research of my own and I soon discovered that my symptoms could be controlled simply by the food I put in my body.

His second failed drugs test was in January 2010, with current club Fiorentina; Mutu failed a doping test after the Florence sides match with Lazio.

It's a sad sad world when a fucking drug cheat is the A side and the warrior who just wants to fight in his actual weight class can't be the A side.

Zagreb midfielder Arijan Ademi failed a drug test in the wake of his side's shock 2 - 1 win in their opening Champions League fixture against the Gunners on September 16.

I'm terrified to fly, but it got me to and from St. Louis w / o a care in the world — it isn't a drug, there are no side effects accept feeling totally calm.

She said she talked to the doctor and he didn't think I would have any side effects since I already had the drug in my system and it would only help me start to feel better.

Her side of the issue is understandable and My side of the issue is understandable but it leaves a rift in our relationship that cant be filled by money or drugs, ive tried... im still trying.

I'd caution against immediately jumping into using herbs as there may be side effects and drug interactions, and in many cases, galactogogues aren't necessary to increase / maintain supply.

Thus, a baby born to a mother on this drug during the pregnancy, will have large amounts in his body, and even the small amount added during breastfeeding may result in significant accumulation and side effects.

I was told on some occasions to stop because of the antibiotics I was on, but I rang the Drugs in Breastmilk helpline run by the BFN (Breastfeeding Network) and they told me I could still nurse with that particular drug, but that doctors were largely ill - informed and tended to err on what they would call «the safe side» ie to stop feeding and use formula!

Naloxone can reverse a heroin or other opiate drug overdose within minutes, but it has no effect on people who do not have an opiate drug in their system and side effects are rare, according to information from the DuPage Narcan Program given to Orland Park trustees.

But after more than two years of meetings and tens of thousands of dollars spent in consulting fees and administrative costs, the district finally put together its Rangers in the Parks program: four unarmed souls on bikes to patrol the gang - and drug - infested Garfield Park on the city «s West Side.

Let's look more at the benefits and side effects of this very common drug in labor and delivery.

Are you suggesting that subtle changes in microbiome should now be listed as a side effect and affect the approval of drugs to treat serious problems like schizophrenia, diabetes, thyroid dysfunction, and rheumatoid arthritis?

Although none of the groups reported on drug side effects, while Guo who tested only breastfed infants reported on significant decrease in infant crying, and decrease in depressive symptoms at one month and at two months respectively, Sung who tested both formula fed and breastfed infants reported on increase crying in the probiotic treated infants (particularly in the formula fed infants) compared to placebo with no effect on maternal depressive symptoms.

In 2009, the FDA issued a warning about the drug's possible side effect, a potentially permanent movement disorder called tardive dyskinesia, which can resemble Tourette's Syndrome or Parkinson's disease.

Many of the epidural side effects mentioned below are not improved with low - dose or walking epidurals, because women using these techniques may still receive a substantial total dose of local anesthetic, especially when continuous infusions and / or patient - controlled boluses (single large doses) are used.34 The addition of opiate drugs in epidurals or CSEs can create further risks for the mother, such as pruritus (itching) and respiratory depression (see below).

The drugs used in labor epidurals are powerful enough to numb, and usually paralyze, the mother's lower body, so it is not surprising that there can be significant side effects for mother and baby.

Other common side effects of epidurals include: inability to pass urine (and requirement for a urinary catheter) for up to two - thirds of women; 38 itching of the skin (pruritus) for up to two - thirds of women administered an opiate drug via epidural; 39, 40 shivering for up to one in three women; 41 sedation for around one in five women; 42 and nausea and vomiting for one in 20 women.43

But by the 1980s, Chicago's West Side was suffering, and in Garfield Park, drugs and weeds flourished more reliably than art and roses.

The side effects of the drug being used constantly results in the need for a C - section.

Because weight loss is a commonly noted side effect of fluoxetine use in adults, it is possible that the drug acts directly to limit weight gain in infants who receive it through breast milk.

Two case reports and two small case series subsequently have provided reassuring evidence regarding the limited amount of drug transferred to the infant through breast milk and the lack of adverse side effects noted in infants by nursing mothers.5 — 8