Sentences with phrase «in earlier stage disease»

Not exact matches

Still, more drugs are in late - stage trials that could have an impact on the disease, and researchers are pinning hopes on diagnosing the disease early, before symptoms even show up.

Years ago, when Mass Design was in the early stages of planning and designing Butaro Hospital in the Burera District of Rwanda, it faced a serious design challenge: To reduce the transmission of airborne diseases like TB.

Our goal is to complement the current strategic interest of Chiesi Farmaceutici in the space of rare diseases by investing in early stage opportunities and accelerate the expansion of the Chiesi network in the US among universities, venture capital investors, rare disease patient organizations and start - ups developing treatments for rare diseases.

BioNTech hit the headlines in July when its experimental personalized cancer vaccine, tailored to the tumors of individual patients, kept disease in check in an early - stage clinical trial.

A married retired man who finds his wife sexually unattractive tracks down a college girlfriend, a widow in the early stages of Alzheimer's disease, and the two begin a passionate affair.

As defined by Custer in the early 1970s, the disease has three stages.

«I'm sorry, but f**k cancer,» Kerr said in France after winning the contest staged in memory of LET player Cassandra Kirkland, who died earlier this year at age 32 from lung cancer, and just days after former LPGA Tour golfer Kelli Kuehne's mother passed away from the disease.

Those diseases are routinely prevented or cured in their early stages.

In the early stages, Paget's disease can look like a normal rash related to irritation from your bra.

[210] By then Wilson was the last surviving member of Attlee's cabinet, [211] and the unveiling of the statue would be one of the last public appearances by Wilson, who was by that point, in the early stages of Alzheimer's Disease and died at the age of 79 in May 1995.

Comparing a new patient's information with millions of other cases, Patient Rescue might be able to predict that they are in the early stages of a disease that has not yet become symptomatic, for example.

24 Love and Other Drugs, a film by Edward Zwick, director of the 2006 film Blood Diamond, depicts an artist named Maggie (Anne Hathaway) in the early stages of Parkinson's disease.

In particular, Parkinson's disease happens to be something that, before you can diagnose early stage Parkinson's in any other way, you can literally take someone speaking over the telephone and analyze it really quicklIn particular, Parkinson's disease happens to be something that, before you can diagnose early stage Parkinson's in any other way, you can literally take someone speaking over the telephone and analyze it really quicklin any other way, you can literally take someone speaking over the telephone and analyze it really quickly.

The combination of changes in oxidised, nitrated and sugar - modified amino acids in blood enabled early stage detection and classification of arthritis — osteoarthritis, rheumatoid arthritis or other self - resolving inflammatory joint disease.

Studies on the origins of BSE — a fatal disease marked in the early stages by loss of balance — gained urgency with the 1996 emergence in humans of the BSE - like new variant Creutzfeldt - Jakob disease (nvCJD).

In her opinion, it remains essential to screen aggressively for breast cancer in hopes of catching the disease in an early, treatable stagIn her opinion, it remains essential to screen aggressively for breast cancer in hopes of catching the disease in an early, treatable stagin hopes of catching the disease in an early, treatable stagin an early, treatable stage.

«Ultrasound enables you to screen a larger population, and that in turn means that life - threatening cardiovascular diseases can be detected at an earlier stage,» says Magnus Cinthio, senior lecturer in biomedical engineering and one of the researchers leading the work.

This will improve the ability to detect an active infection more easily than before so that healthy people with Lyme disease antibodies in their blood do not receive unnecessary antibiotic treatment and so that appropriate treatments can be initiated at an early stage.

Electrophysiological testing to measure peripheral nerve conduction properties is not a viable alternative because current methods lack the sensitivity required to detect damage to small, unmyelinated fibers, especially in early stages of disease.

«An estimated 220,000 men are expected to be newly diagnosed with prostate cancer each year in the United States, and the majority will have early - stage disease at low risk for recurrence,» Lee said.

As rates of skin cancer, or melanoma, rise for men and women in the United States, health experts are debating the effectiveness of annual total body examinations in helping to detect the disease in its earlier stages.

The trial has also included 10 HER -2-negative breast cancer patients, all of them in early stages of the disease.

In the early stages of the disease, however, tau proteins undergo changes that nudge them off microtubules.

The biological molecules increase the sensitivity of the material, meaning it can sense extremely low concentrations of substances, such as antibodies, and thus potentially detect diseases in their earliest stages.

«Patients diagnosed with early - stage prostate cancer — and that's the vast majority of patients with this disease — face many treatment options that are thought to be similarly efficacious,» said Ronald C. Chen, MD, MPH, UNC Lineberger member and associate professor in the UNC School of Medicine Department of Radiation Oncology.

The AUC for those patients was 0.87 for Stage I / IIA, 0.93 for Stage IIB and 0.89 for all early stages of the disease using the combination, pointing to a potential ability to detect disease in those who lack either of those known risk - raising conditions.

The neuroprotective effects of nicotine were studied in a randomized clinical trial involving 67 subjects in the early stages of Alzheimer's disease, where memory was slightly impaired but decision - making and other cognitive abilities remained intact.

«We believe that we have made an important step forward in minimising post-operative complications for patient with early HNSCC, enabling a more accurate identification of the stage of their disease, and reducing the cost to healthcare systems at the same time,» Prof de Bree will conclude.

«Based on the results of this study, the side of origin of CC [colon cancer](left vs. right) should be acknowledged as a criterion for establishing prognosis in both earlier and advanced stages of disease.

Adding two blood - borne proteins associated with cancer cell migration increases the predictive ability of the current biomarker for pancreatic cancer to detect early stage disease, a research team from The University of Texas MD Anderson Cancer Center reports in the Journal of the National Cancer Institute.

As well as revealing step by step how disease and infection can aggravate and accelerate the early stages of Alzheimer's, Perry and his colleague Clive Holmes have begun a pioneering trial in 40 people to see if a drug that acts to dampen inflammation in the body can help delay the progress of the brain disease.

Although tau imaging is still in its earliest stages, Ryan hopes that such imaging will accelerate drug development and that finding a blood - based biomarker for Alzheimer's to reveal risk (much like cholesterol serves as a marker for cardiovascular risk) will change the field dramatically in terms of how doctors can diagnose the disease.

The first, called bio-bar-code assays, relies on nanoparticles designed to attach themselves to specific disease - causing proteins; these will vastly improve a doctor's ability to detect diseases like cancer and Alzheimer's in their early stages and to identify pathogens like anthrax.

The team is now planning a larger trial in people who have earlier stages of the disease.

«Tackling childhood diseases at an early stage allows for a healthier general population in the long run.»

The Duke medical researchers and ecologists who have joined that project hope to identify which species flourish in early stages of the human microbiome, how they are influenced by the consumption of breast milk, and what role they play in critical diseases affecting infants as well as in chronic diseases that occur later in life.

«Physical therapy not associated with improvements in patients with early stages of Parkinson's disease.»

These tangle - like structures appear at early stages of Alzheimer's and are not found in other neurodegenerative diseases such as Parkinson's disease.

Pancreatic cancer has the lowest survival rate among all major cancers, largely because physicians lack diagnostic tools to detect the disease in its early, treatable stages.

She recently co-authored research appearing in the peer - reviewed Journal of Alzheimer's Disease that used state - of - the - art accelerometers to track daily physical activity of healthy people and those in the early stage of AD.

Once stem cells can be grown and differentiated in a controlled way to replace degenerated cells and repair tissues, medical science may then be able to diagnose and cure many intractable diseases at their earliest stages, such as type 1 diabetes, Parkinson's disease, various cardiovascular diseases, liver disease, and cancer.

«Our findings show that a specific genetic marker (known as allele * 2 of the HS1, 2 A enhancer region) influences not just disease activity in RA patients, but also response to therapy in the early stages of their disease,» said lead investigator Dr Gabriele Di Sante of the Institute of Rheumatology and Related Sciences, Catholic University of the Sacred Heart, Rome, Italy.

Dr Schneck and coauthors add, «The most common age - related eye diseases (glaucoma, age - related macular degeneration, and diabetic eye disease) all produce blue - yellow color vision anomalies, at least in the preclinical or early stages.»

A specific genetic marker influences response to therapy in the early stages of RA; a link thought to be due to the gene activating a cell - signalling protein involved in the inflammatory disease process.

Motor neurons in the brain are not lost until the final stages of the disease, but starting very early in the process they appear to exist in a dysfunctional form.

In current clinical practice, no biomarkers exist for diagnosing early - stage disease.

Future refinements should sharpen the method's ability to accurately identify Alzheimer's disease at an early stage — prior to the onset of clinical symptoms — in a primary care setting, with just a simple blood extraction.

Should doctors treat patients in early stages of Parkinson's disease, when drug side effects may be worse than the symptoms they alleviate?

But the early stage work is promising, he says, because it holds out hope that doctors will soon be able to image breast cancer with several techniques simultaneously, significantly increasing the chances of spotting the disease in its earliest stages.

Through studies like these, Jirtle says, «we're beginning to understand how a molecule present at the very earliest stages after fertilization can in effect be remembered into your twenties and thirties and maybe give rise to diseases.