Sentences with phrase «in early embryogenesis»

Here, we exploit functional genomic strategies to identify Ta and Tbx16 targets in early embryogenesis.

Vastenhouw NL, Schier AF Bivalent histone modifications in early embryogenesis.

Shp2, for example, plays an essential role in early embryogenesis and is also known to play a role in cancer.

Not exact matches

In order to elucidate the significance of early epigenetic modifications on the development of neural cells during embryogenesis in the mouse, Götz and her colleagues specifically inactivated the gene UhrfIn order to elucidate the significance of early epigenetic modifications on the development of neural cells during embryogenesis in the mouse, Götz and her colleagues specifically inactivated the gene Uhrfin the mouse, Götz and her colleagues specifically inactivated the gene Uhrf1.

When they had a closer look into the embryos, the team found that several important developmental genes that are normally switched off during early embryogenesis were turned on in embryos without H3K27me3.

Each colored circle in the image shows one of the embryo's cells, and the corresponding tail indicates that cell's movement over a short time interval during early embryogenesis (at around 3 hours post-fertilization).

Therefore the researchers used a variety of genetic tools in fruit flies to remove the enzyme that places H3K27me3 marks and discovered that embryos lacking H3K27me3 during early development could not develop to the end of embryogenesis.

Our recent analysis of SAC signaling in C. elegans revealed that there is a gradual increase in SAC strength during early embryogenesis, as cells become smaller and smaller (1).

Interestingly, events early in the life history of corals, prior to the initiation of calcification, such as fertilization, embryogenesis, larval survival and settlement are not overly affected by high acidity.

Tachibana, M.; Sugimoto, K.; Nozaki, M.; Ueda, J.; Ohta, T.; Ohki, M.; Fukuda, M.; Takeda, N.; Niida, H.; Kato, H.; Shinkai, Y. G9a histone methyltransferase plays a dominant role in euchromatic histone H3 lysine 9 methylation and is essential for early embryogenesis.

The data show that the presence of a modification of an evolutionary conserved structure, such as the presence of a rib on the seventh vertebra (a cervical rib, i.e. a change in the number of cervical vertebrae), can be used as a reliable indicator of disturbances of early embryogenesis (Collaboration with Liliane Wijnaendts, Free University Medical Centre (VUMC).

We estimate that approximately three base substitution mutations occur per cell per cell - doubling event in early human embryogenesis and these are mainly attributable to two known mutational signatures.

Global analyses of mRNA translational control during early Drosophila Embryogenesis X. Qin, S. Ahn, T.P. Speed, G.M. Rubin Genome Biology In Press Supplemental datasets

We propose that a defect in the CNV formation process is responsible for the «CNV - mutator state,» and this state is dampened after early embryogenesis.

«Most of the epigenome is set during embryogenesis and early development,» says Jean - Pierre Issa, director of the Fels Institute for Cancer Research and Molecular Biology at Temple University in Philadelphia.

These genes have been also implicated in the gastrulation phase of embryogenesis [55] indicating that «Time Series» clusters provide a comprehensive collection of genes expressed at specific stages of ES cell differentiation and early embryonic development.

Whitehead Institute researchers have determined that poly (A) tails on messenger RNAs (mRNAs) shift their role in the regulation of protein production during early embryogenesis.

In mammals, inductive signaling early in embryogenesis creates a small number of primordial germ cells (PGCsIn mammals, inductive signaling early in embryogenesis creates a small number of primordial germ cells (PGCsin embryogenesis creates a small number of primordial germ cells (PGCs).

Such cells provide a better model of early human embryogenesis than conventional ESCs in later stages of development.