Sentences with phrase «in embryonic tissue»

After analysing the presence of NANOG in different mouse tissues by immunohistochemistry, the CNIO team demonstrated that, in addition to being present in embryonic tissue, this factor is also found in stratified epithelia such as the esophagus, skin or vagina.

Not exact matches

A seriously ill person in need of embryonic stem cells to repair damaged tissue.

In a study in the journal Science, researchers explain how they used mouse embryonic stem cells and microchip technology to create heart muscle tissue that actually beatIn a study in the journal Science, researchers explain how they used mouse embryonic stem cells and microchip technology to create heart muscle tissue that actually beatin the journal Science, researchers explain how they used mouse embryonic stem cells and microchip technology to create heart muscle tissue that actually beats.

The decision whether the maternal or the paternal version is shut down occurs early in embryonic development — one reason, why for long it was thought that the pattern of active alleles is nearly homogeneous in the various tissues of the organism.

In females, a similar embryonic tissue called the Müllerian duct develops into the fallopian tubes, uterus and vagina.

Yoshiki Sasai at the RIKEN Center for Developmental Biology in Kobe, Japan, and colleagues encouraged embryonic stem cells to develop into retinal cells, and then grew them alongside a protein matrix to promote the formation of tissue.

A new study shows that many genes are abnormally regulated in cloned embryos, especially in extra embryonic tissue and the placenta.

ERRORS have occurred in a type of stem cell that could be used instead of embryonic stem cells — and in tissues made from them.

Scientists have focused for decades on the role of biochemical cues in embryonic development, Campàs said, because no techniques existed to measure the mechanical cues that cells are exposed to during the formation of tissues and organs.

Now, many research advocates are wondering how Price's mix of views might play out in the new administration's approach to a wide range of issues, including funding, research involving human embryonic stem cells and fetal tissue, and the appointment of a new NIH director.

Those embryonic cells migrate in the embryo and contribute to tissues involved in the fight - or - flight response, facial development and coloring.

The immediate payoff was a commercialization deal in age - related macular degeneration in which Pfizer became the first big pharma company to make a move into the use of embryonic stem cells as the basis for a tissue regeneration therapy.

In order to overcome the limited ability of the neurons of the adult nervous system to regenerate spontaneously, cell replacement strategies employing embryonic tissue transplantation show attractive potential.

In addition to providing an alternative to embryonic stem cells for potential use in regenerating diseased tissues, iPS cells are being used to learn more about diseases, especially diseases driven by mutated geneIn addition to providing an alternative to embryonic stem cells for potential use in regenerating diseased tissues, iPS cells are being used to learn more about diseases, especially diseases driven by mutated genein regenerating diseased tissues, iPS cells are being used to learn more about diseases, especially diseases driven by mutated genes.

In 2004 they devised a way to coax embryonic stem cells to turn into transplantable RPE tissue.

On the other hand, the problem is, you know, with embryonic stem cells, they haven't been able to get stem cell lines from livestock animals that can proliferate in that way, without just sort of veering up in their own direction and turning into, instead of muscle, turning into brain tissue or bone tissue or something else.

Whales today don't have digit muscles, but some fishes gradually acquired embryonic digit - forming tissue in their fin muscles.

These include a family of signaling molecules called protocaderins, which regulate neuronal development and short - range interactions between neurons, and a family of transcription factors called zinc fingers, which are mainly expressed in embryonic and nervous tissues and are thought to play roles in brain development.

The results help fill in the scientific puzzle kicked off by Dolly's cloning, which proved that mammalian egg cells were capable of dissolving the genetic roadblocks that limit the potential of most adult cells to give rise to only a single type of tissue — that of the organ from which they hail — whereas embryonic stem cells have the potential to become virtually any kind of body tissue.

In contrast to embryonic stem cells, when adult stem cells divide, their offspring are only able to develop at the same site and in certain tissue typeIn contrast to embryonic stem cells, when adult stem cells divide, their offspring are only able to develop at the same site and in certain tissue typein certain tissue types.

They propose that normal tissue becomes primed for cancer when oncogenes are activated and tumor suppressor genes are silenced or lost, but that cancer develops only when a cell in the tissue reverts to a more primitive, embryonic state and starts dividing.

His work involves high - resolution imaging of chick embryonic tissue slices to study the cell - biological mechanisms driving neurogenesis in the spinal cord, for which Dr. Das played an instrumental role in pioneering new imaging technology.

But if homologous recombination could be worked out in human (embryonic) stem cells, then cardiomyocytes with mutations in ion channels could be derived, as well as a large number of other very useful disease models of other tissues.

Another gene active in the peduncle is related to one that, in higher organisms, functions prominently in embryonic heart tissue.

In another series of experiments, they inserted a green fluorescent protein into the tissues that give rise to blood and lymph vessels in embryonic zebrafisIn another series of experiments, they inserted a green fluorescent protein into the tissues that give rise to blood and lymph vessels in embryonic zebrafisin embryonic zebrafish.

The result — the second such finding in the past year — suggests that similar cells from human testicles might have similar powers, paving the way to creating replacement tissue for men who have suffered damage from heart attacks or other injuries and avoiding some of the controversy surrounding embryonic stem cells (ESC).

In vitro experiments used human colon carcinoma cells with and without MMP9 and mouse embryonic fibroblasts, which are connective tissue cells that make the extracellular matrix and collagen and play an important role in tissue repaiIn vitro experiments used human colon carcinoma cells with and without MMP9 and mouse embryonic fibroblasts, which are connective tissue cells that make the extracellular matrix and collagen and play an important role in tissue repaiin tissue repair.

«It assumes the difficult task of maintaining the protein balance in a quickly dividing tissue and an acidic environment during the embryonic phase.

Handa's team found that beads tagged with thalidomide bound to a little - known protein called cereblon, which is expressed widely in both embryonic and adult tissues.

In September California's Democratic governor, Gray Davis, crystallized the politics by signing the first state legislation permitting research on the embryonic cells, the master cells that can morph into any tissue in the bodIn September California's Democratic governor, Gray Davis, crystallized the politics by signing the first state legislation permitting research on the embryonic cells, the master cells that can morph into any tissue in the bodin the body.

In 1983, Beddington set up her own lab at Oxford and became one of the first scientists to demonstrate that embryonic stem cells can give rise to any tissue found in a developed bodIn 1983, Beddington set up her own lab at Oxford and became one of the first scientists to demonstrate that embryonic stem cells can give rise to any tissue found in a developed bodin a developed body.

A team of researchers from DuPont added so - called morphogenic genes — known from basic research to promote the production of embryonic tissue — to the other genes being transformed (in this case to express green fluorescent protein as a marker of transformation).

The ERK pathway plays a critical role in embryonic development and tissue repair because it instructs cells to multiply and start dividing, but when over activated cancer growth occurs.

I don't know too many other consortia which can integrate expertise in embryonic and tissue stem cell biology, tissue regeneration and repair, bioengineering and nanotechnology, materials science, genomics and bio-informatics.

By contrast, most embryonic and induced pluripotent stem cells are more restricted in their developmental potential, able to form embryonic cell types, but not extra-embryonic tissues.

In contrast, embryonic stem cells are pluripotent which means they can make all the cells of the organism, but typically not the extra-embryonic tissue.

Several years ago, one of the students in Verma's lab noticed that BRCA1 is very active in the neuroectoderm, a sliver of embryonic tissue containing neural stem cells that divide and differentiate into the brain's vast assortment of cell types and structures.

Previous research in rodent disease models has shown that transplanted oligodendrocyte precursor cells derived from embryonic stem cells and from human fetal brain tissue can successfully create myelin sheaths around nerve cells, sometimes leading to dramatic improvements in symptoms.

This has always been a worry with tissues produced from embryonic stem cells, as these have the capability to form tumours if any are left in their original state in the transplanted tissue.

A group that included researchers at the Wellcome Trust Sanger Institute and the University of Cambridge, both in the United Kingdom, developed a possible treatment for A1ATD by first reprogramming a skin cell from a patient into iPS cells, which are embryonic - like cells that can develop into many tissue types.

Both teams successfully used these to reprogramme skin cells in a lab dish into cells resembling embryonic stem cells, which have the ability to turn into any tissue of the human body.

The so - called WNT proteins carry messages into cells and regulate embryonic and adult tissue in mammals, including humans.

However, malformation of skeletal bones during embryogenesis also occurs in FOP patients and illustrates that the underlying genetic mutation occurs in a gene with functional importance in regulating chondro - osseous differentiation during embryonic skeletal development as well as in adult musculoskeletal tissues.

The research used skin samples from five men to create what are known as induced pluripotent stem cells, which closely resemble embryonic stem cells in their ability to become nearly any tissue in the body.

In 1963 Pietro Angeletti and one of us (Levi Montalcini), who were then at the Istituto Superiore di Sanità in Rome, dissected sensory and sympathetic ganglia into their cellular components: neurons, glial cells (which support and nourish the neurons) and fibroblasts (embryonic connective - tissue cellsIn 1963 Pietro Angeletti and one of us (Levi Montalcini), who were then at the Istituto Superiore di Sanità in Rome, dissected sensory and sympathetic ganglia into their cellular components: neurons, glial cells (which support and nourish the neurons) and fibroblasts (embryonic connective - tissue cellsin Rome, dissected sensory and sympathetic ganglia into their cellular components: neurons, glial cells (which support and nourish the neurons) and fibroblasts (embryonic connective - tissue cells).

According to the researchers, these findings suggest that differences in shape from cell - to - cell within a tissue are key to their ability to jam and unjam — and that this process appears to drive biological events including embryonic development, wound healing, and, potentially, cancer cell invasion.

For example, there is no equivalent of indefinitely self - renewing embryonic stem cells in the human embryo — these are instead transient cells that very quickly specialise to become the precursors of tissues in the embryo.

One way is to identify transcription factors, and one way to identify transcription factors in microRNAs that can be used for reprogramming, is to screen for them through microarrays or RNA sequencing within the embryonic brain tissue.

In this edition, we're going to take a look at a very interesting tool that can be used for creating (excuse the pun) specific, targeted DNA modifications in transgenic animals, embryonic stem cells, and / or tissue - specific cell types: Cre - lox recombinatioIn this edition, we're going to take a look at a very interesting tool that can be used for creating (excuse the pun) specific, targeted DNA modifications in transgenic animals, embryonic stem cells, and / or tissue - specific cell types: Cre - lox recombinatioin transgenic animals, embryonic stem cells, and / or tissue - specific cell types: Cre - lox recombination.

Probably a number of embryonic genes, after being turned off for decades, are reexpressed in cancer cells, enabling those cells to regain their embryonic capacity to move around and invade other tissues.»