The dog has already played an important role
in emerging therapies for inherited blindness in humans and similarities in disease phenotype and eye structure and function between dog and man, together with the increasingly sophisticated genetic tools that are available for the dog, mean that the dog is likely to play an ever increasing role in both our understanding of the normal functioning of the eye and in our ability to treat inherited eye disorders.
Not exact matches
Companies are also finding that using M&A to acquire R&D capabilities is an effective way to build positions
in emerging technologies such as gene
therapy and biosimilars.
Kite is one of the leading players
in the
emerging field of CAR T, and is competing with rivals Novartis AG, Juno Therapeutics Inc and Bluebird Bio Inc
in a race to get the first approved
therapy.
The research shows that millions more around the world should be taking pills or benefiting from
therapy — just one person
in 27
in emerging - market countries get proper treatment.
The researchers found that seventeen (43 \ %) had been misdiagnosed by their referring physicians as being
in PVS; thirteen (33 \ %) slowly
emerged from the vegetative condition during rehabilitation
therapy; and only ten (25 \ %) remained
in the vegetative state.
Soon I was an
emerging expert on Early Intervention, an Illinois state program of low - cost,
in - home
therapy services for kids age 0 - 3.
Although parents
in recent decades have been almost excruciatingly concerned that older sibs not feel replaced by younger ones, the issues continue to
emerge in therapy with adults.
A new study
in Journal of Neurophysiology reports that peripheral nerve stimulation
therapy can reverse SCI - associated nerve deterioration, potentially improving the benefits of current and
emerging rehabilitation treatments.
Even if positive results
emerge from these trials, ACT will still face major challenges
in getting an ES - cell - based
therapy approved for wider use.
Early
in the 20th century, radiation
therapy was also an
emerging cancer treatment, and the nation's preeminent cancer pathologist, James Ewing, staunchly favored treating patients with this promising new method.
Despite being curable with multidrug
therapy, leprosy still persists
in many developing countries, with more than 200,000 new cases every year and increasing drug - resistant strains of the leprosy bacterium, Mycobacterium leprae,
emerging.
This is important because it makes it possible to model almost any autoimmune disease, evaluate new drug
therapies, and even identify novel targets
in the
emerging area of cancer immunotherapies.
Over the past few years, researchers have seen resistance against artemisinin derivatives — which are combined with other drugs
in so - called artemisinin - based combination
therapies —
emerge in Cambodia,
in an area along the border with Thailand.
Nonalcoholic fatty liver disease (NAFLD)-- induced hepatocellular carcinoma (HCC) is an
emerging malignancy
in the developed world; however, mechanisms that contribute to its formation are largely unknown, and targeted
therapy is currently not available.
Still, by identifying the human hairless gene as an important master switch
in regulating cell death
in a hair follicle — a discovery that could lead to gene
therapies for unwanted hair growth — Christiano
emerged as a new star
in the field, and a glamorous one.
The technical advances
emerging from gene
therapy have fueled the larger fields of cell and immune
therapy, where DNA, immune molecules, and viruses are all elements to be manipulated,
in concert or one at a time.
The article
in the journal Molecular
Therapy — Nucleic Acids titled «As Technologies for Nucleotide Therapeutics Mature, Products
Emerge» describes the analysis of more than 60,000 research publications related to oligonucleotide
therapies.
«There is no obvious breakthrough
therapy emerging in the coming years.
Among the interesting topics covered
in Pathways are: the changing role of the patient
in the total health equation and the ways
in which decentralized information is affecting their expectations and demands; the dearth of pipeline products among international pharmaceutical companies against a backdrop of increased research and development spending; the dynamics of
emerging markets and their rising demand for
therapies in chronic disease; the value of drugs and biotechnology solutions within the context of global economic realities.
This webinar is the third
in a series focusing on the cancer pathways that support tumor development, the
emerging research
in identifying and targeting these pathways, and innovations
in the development of increasingly effective cancer
therapy options.
This webinar is the second
in a series (see Part 1 here) focusing on the cancer pathways that support tumor development, the
emerging research
in identifying and targeting these pathways, and innovations
in the development of increasingly effective cancer
therapy options.
Thus, finding new targets for drugs already
in use to treat other diseases,
in other words drug repurposing, is an
emerging area
in developing anti-cancer
therapies.
For these reasons,
in this issue's special report, «Calming a Child's Mind,» we highlight
emerging therapies for the three most prevalent childhood disorders — anxiety, behavior or conduct disorder, and attention - deficit hyperactivity disorder (ADHD).
Tom Solomon, director of the United Kingdom's Health Protection Research Unit
in Emerging Infections based at the University of Liverpool, says he is also considering a trial of the
therapy in humans.
«As with many
therapies in medicine today, evidence is
emerging that a more personalized approach is likely the best approach when determining how much vitamin D is optimal for an individual.
Stem and progenitor cell (PC)
therapy that promotes neoangiogenesis [formation of blood vessels] is an
emerging treatment modality
in PAD,» according to background information
in the article.
Starting
in 2010, cancer immunotherapy has
emerged as the «new» breakthrough approach to cancer
therapy but this is actually the fruit of decades of labor and CRI has been steadfastly behind that research from the beginning.»
This year's Action Award honorees include global leaders
in the fight to end cancer as we know it; a world leader
in advancing the
emerging field of regenerative medicine and game - changing cell
therapy medical treatments; the president of a non-profit group focused on developing cures for chronic, debilitating and fatal diseases; a sickle cell and stem cell advocate and founder / science administrator of the Axis Advocacy; and the founding director of the Institute for Integrated Cell - Material Sciences (iCeMS) at Japan's Kyoto University.
This specificity
in treatment fits with an
emerging approach
in cancer treatment nationwide, known as personalized medicine,
in which the
therapies for each patient are selected based on the genes altered
in their tumors.
Other Institutions also belong to the Campus: the University of Milan; Cogentech, an IFOM - IEO consortium committed to developing leading genomic technologies (nanotechnologies, proteomics, bioinformatics, disease models), the European School of Molecular Medicine (SEMM), that organizes training
in emerging sectors of Biomedicine, offering the first European PhDs
in Molecular Medicine, Medical Nanotechnologies, Foundations of the Life Sciences and their Ethical Consequences; Genextra, a biotech company whose mission is to develop new
therapies against cancer and aging - related disease; Biopolo, a not for profit company involved
in the technological transfer of basic research to the productive system.
This newly restructured committee will aid the PMC
in advancing the era of personalized medicine, specifically by critically evaluating
emerging applications of science and technology to patient care for risk assessment,
therapy and prevention.
ViaCyte, a private company that has
emerged as a leader
in the field of regenerative medicine, is currently focused on developing a novel cell
therapy for the treatment of diabetes.
«Thanks to improvements
in the understanding of AML biology, a multiplicity of so - called targeted
therapies and
therapies based on differential pathophysiology of leukemic stem cells compared with normal counterparts have
emerged,» noted Richard M. Stone, MD, clinical director of the Adult Leukemia Program at Dana - Farber Cancer Institute
in Boston, and colleagues, writing
in a review for the ASCO 2017 Educational Book.
Cell
therapy is an
emerging pillar
in healthcare with the potential to provide curative solutions to a wide range of indications.
NYC Neuromodulation 2017 will focus on technologies and mechanism for advanced brain stimulation
in areas that include transcranial direct current stimulation (tDCS), transcranial alternating current stimulation (tACS), transcranial magnetic stimulation (TMS), high - definition transcranial direct current stimulation (HD - tDCS), electroconvulsive
therapy (ECT), deep brain stimulation (DBS), and other
emerging areas.
Muthumani's research interest is
in the area of immune approaches to
emerging infectious diseases and immune
therapy approaches for the treatment cancer.
Dr. Bosarge was honored by the Regenerative Medicine Foundation (RMF) at its annual Stem Cell and Regenerative Medicine Action Awards for his efforts
in advancing the
emerging field of regenerative medicine and game - changing cell
therapy medical treatments.
As part of the internationally recognized University of Chicago Comprehensive Cancer Center (UCCCC), we participate
in national clinical trials testing new and
emerging therapies.
The U-M cystic fibrosis program is the largest program of its kind
in the state, accredited by the Cystic Fibrosis Foundation with leadership
in numerous research studies investigating
emerging therapies.
AAV gene
therapy vectors are
emerging as the gene transfer vehicle with high potential for use
in the CNS as they transduce post mitotic cells that mediate the sustained, long term gene expression required
in chronic progressive diseases.
Progress
in the evolving field of immunotherapy and the
emerging field of viral - based gene
therapy herald a promising new era
in the field of liver cancer.
My work is
in the
emerging field called: Targeted Cancer
Therapy (TCT).
It is also the first
in an
emerging class of
therapies called «checkpoint blockade,» which enhance the immune system's ability to attack cancer by interfering with immunological checkpoints that slow or stop immune cell activation and proliferation
in the presence of tumors or chronic viral infection.
«We are encouraged by the preclinical data
emerging on SRK - 015, including the effects upon fast - twitch muscle fibers that are particularly relevant for SMA as well as its selectivity profile, which may be very important when considering chronic
therapy in children,» said Karen S. Chen, PhD, Chief Scientific Officer of the SMA Foundation and a co-author of the study being presented at the Cure SMA Annual Conference.
2:15 PM From
emerging new
therapies in children to defining and implementing healthcare needs
in adults: Cradle to grave management
in Achondroplasia.
Recent spread of artemisinin resistance and
emerging piperaquine resistance
in Southeast Asia show that artemisinin combination
therapy, such as dihydroartemisinin - piperaquine, are losing clinical effectiveness, prompting investigation of drug resistance mechanisms and development of strategies to surmount
emerging anti-malarial resistance.
Background: As the prevalence of artemisinin - resistant Plasmodium falciparum malaria increases
in the Greater Mekong subregion,
emerging resistance to partner drugs
in artemisinin combination
therapies seriously threatens global efforts to treat and eliminate this disease.
Myelosuppression is a well - established side effect of current AML
therapies, with prolonged events leading to an increased risk of infections and death.44 Consequently,
therapies that preferentially kill leukemic cells over normal bone marrow cells are urgently required, and the overexpression of CD123 on AML leukemic stem cells and blasts compared with normal hematopoietic cells contributes to its attractiveness as a therapeutic target
in this disease.6, 45 However, severe myelosuppression and myeloablation have
emerged for some investigational CD123 - targeted treatment modalities.
In fact, some emerging therapies for depression use electrical stimulation of the vagus nerve to trigger changes in the brain.&raqu
In fact, some
emerging therapies for depression use electrical stimulation of the vagus nerve to trigger changes
in the brain.&raqu
in the brain.»
«
In the Womens Health Initiative (WHI) trial, when women got seven years of estrogen alone, there was no increased risk of breast cancer, but after four to five years on combined hormone
therapy, the risk
emerges,» she says.