Sentences with phrase «in endothelial»
... The impairment in endothelial function is significant after just one hour of sitting.
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High homocysteine levels can result in endothelial dysfunction (a narrowing of the arteries) which in turn is believed to be a precursor of atherosclerosis.
Activation of Nrf2 in endothelial cells protects arteries from exhibiting a proinflammatory state.
Rizza, Stefano, et al. «Citrus polyphenol hesperidin stimulates production of nitric oxide in endothelial cells while improving endothelial function and reducing inflammatory markers in patients with metabolic syndrome.»
Over time, elevated homocysteine levels can result in endothelial injury or blood vessel inflammation.
Research shows that L - theanine can increase nitric oxide production in endothelial cells15.
Fructose Induces the Inflammatory Molecule ICAM - 1 in Endothelial Cells.
Fatty acids differentially influence phosphatidylinositol 3 - kinase signal transduction in endothelial cells: impact on adhesion and apoptosis.
Eating an anti-inflammatory diet like you do is always the best first step to eliminating or at least decreasing inflammation in the endothelial wall but may not be enough in some cases.
Magnesium deficiency in vitro enhances free radical - induced intracellular oxidation and cytotoxicity in endothelial cells
All three studies on walnuts showed an improvement in endothelial function, arterial function — this so - called flow - mediated dilation measured in the arm.
Selectively expressed in endothelial cells.
Activation of Signal Transducer and Activator of Transcription 1 (STAT1) Is Not Sufficient for the Induction of STAT1 - dependent Genes in Endothelial Cells: COMPARISON OF INTERFERON --LCB- gamma -RCB- AND ONCOSTATIN M
However, in this investigation no isoform of p73 was found in endothelial tissues.
In addition, the team noted that soraphen A could be a useful chemical tool for studying fatty acid metabolism in endothelial cells.
Finally, the anti-inflammatory potential of this compound is demonstrated by its inhibition of both COX - 2 expression and MCP - 1 secretion in endothelial cells.
The new findings build on a 2010 study conducted by Rask - Madsen, which found that insulin resistance only in endothelial cells is sufficient to increase susceptibility to atherosclerosis.
mouse liver, IHC - P, high background in endothelial cells.
«The second step involving Akt activation by R - Ras stabilizes the microtubule cytoskeleton in endothelial cells, creating a steady architecture that promotes lumen formation.»
F: Demonstrates that extensive serial dilutions of central - intermediate and peripheral area HCECs only show telomerase activity in the endothelial peripheral area as taken from mixed aged donors (21 - 52 years).
Expression and function of the homeostatic molecule Del - 1 in endothelial cells and the periodontal tissue.
Dynamics of RhoGTPase activity in endothelial cells induced by addition of nocadozole.
Dr. Rotimi's lab has shown that a polymorphism in the endothelial nitric oxide gene is associated with diabetic retinopathy in Africans.
Mechanisms of H2O2 - induced oxidative stress in endothelial cells.
Expression of angiopoietin - 1 in hypoxic pericytes: regulation by hypoxia - inducible factor - 2alpha and participation in endothelial cell migration and tube formation.
Egg - Derived Peptide IRW Inhibits TNF - α - Induced Inflammatory Response and Oxidative Stress in Endothelial Cells.
The physiological function of von Willebrand's factor depends on its tubular storage in endothelial Weibel - Palade bodies.
Homocysteine - Induced Apoptosis in Endothelial Cells Coincides With Nuclear NOX2 and Peri-nuclear NOX4 Activity.
Receptor - mediated activation of nitric oxide synthesis by arginine in endothelial cells.
Microtubule - targeting agents inhibit angiogenesis at subtoxic concentrations, a process associated with inhibition of Rac1 and Cdc42 activity and changes in the endothelial cytoskeleton.
This study examines long - term changes in endothelial cell density in eyes implanted with Artisan (Ophtec BV) iris - fixated phakic intraocular lens.
Cadmium overkill: autophagy, apoptosis and necrosis signalling in endothelial cells exposed to cadmium.
If we understand the special features of insulin resistance in endothelial cells, we may be able to find more effective treatments against artery damage and cardiovascular disease in people with diabetes.»
The scientists began with a line of mice in which the gene for the insulin receptor has been knocked out in endothelial cells only.
We considered focusing our studies on the peripheral corneal endothelium and endothelial limbus after reports by Schimmelpfenning [16] and Daus et al. [17] indicated a significant increase in endothelial cell density of the peripheral corneal endothelium.
Related to this, the discovery of an increased endothelial cell population in the periphery of the human cornea has prompted an investigation for evidence of the existence of stem - like cells in the endothelial periphery.
They then asked why biglycan expression was increased in the endothelial cells, and found that the promoter region of the gene was de-methylated, meaning the gene was switched on.
These analyses showed that Angiopoietin - 2 is not just affecting angiogenesis, but controls at the same time the production of tumor promoting growth factors in endothelial cells.
The scientists in Augustin's laboratory consequently pursued preclinical tumor therapy experiments, which were aimed at not just blocking angiogenesis, but to also suppress the production of tumor - promoting growth factors in endothelial cells.
«Up to now, the Tie2 receptor has only been known in endothelial cells that line the inside of blood vessels,» Milde said.
«In endothelial cells, glutamine is metabolized to ammonia,» Durante said.
The team then introduced short RNA molecules that deactivate a gene called Id1, which promotes angiogenesis and is active in endothelial progenitors.
In these studies, they used mice that had been specially bred to express a fluorescent green protein in their endothelial cells.
To make their molecular delivery vehicles, the researchers combined the polymersomes with a protein called LRP1, which is abundant in the endothelial cells that make up the blood — brain barrier wall.
The researchers also found that SIRT1 activity in endothelial cells is critical for the beneficial effects of exercise in young mice.
«The effect of the precursors that boost NAD is to counteract the decline that occurs with normal aging, to reactivate SIRT1, and to restore function in endothelial cells to give rise to more blood vessels.»
To do that, they deleted the gene for SIRT1, which encodes the major mammalian sirtuin, in endothelial cells of mice.
In their latest study, Guarente and his colleagues decided to explore the role of sirtuins in endothelial cells, which line the inside of blood vessels.
However, when the researchers knocked out SIRT1 in endothelial cells of 10 - month - old mice, then put them on a four - week treadmill running program, they found that the exercise did not produce the same gains seen in normal 10 - month - old mice on the same training plan.
Not exact matches
It has received attention for its hypolipidaemic and hypocholesterolaemic properties, as well as its ability to lower blood pressure, improve arterial compliance and endothelial function, insulin resistance and weight loss in obesity.