Not exact matches
Important factors that could cause actual results to differ materially from those reflected
in such forward - looking statements and that should be considered
in evaluating our outlook include, but are not limited to, the following: 1) our ability to continue to grow our business and execute our growth strategy, including the timing, execution, and profitability of new and maturing programs; 2) our ability to perform our obligations under our new and maturing commercial, business aircraft, and military development programs, and the related recurring production; 3) our ability to accurately estimate and manage performance, cost, and revenue under our contracts, including our ability to achieve certain cost reductions with respect to the B787 program; 4) margin pressures and the potential for additional forward losses on new and maturing programs; 5) our ability to accommodate, and the cost of accommodating, announced increases
in the build rates of certain aircraft; 6) the effect on aircraft demand and build rates of changing customer preferences for business aircraft, including the effect of global economic conditions on the business aircraft market and expanding conflicts or political unrest
in the Middle East or Asia; 7) customer cancellations or deferrals as a result of global economic uncertainty or otherwise; 8) the effect of economic conditions
in the industries and markets
in which we operate
in the U.S. and globally and any changes therein, including fluctuations
in foreign currency exchange rates; 9) the success and timely execution of key milestones such as the receipt of necessary regulatory approvals, including our ability to obtain
in a timely fashion any required regulatory or other third party approvals for the consummation of our announced acquisition of Asco, and customer adherence to their announced schedules; 10) our ability to successfully negotiate, or re-negotiate, future pricing under our supply agreements with Boeing and our other customers; 11) our ability to enter into profitable supply arrangements with additional customers; 12) the ability of all parties to satisfy their performance requirements under existing supply contracts with our two major customers, Boeing and Airbus, and other customers, and the risk of nonpayment by such customers; 13) any adverse impact on Boeing's and Airbus» production of aircraft resulting from cancellations, deferrals, or reduced orders by their customers or from labor disputes, domestic or international hostilities, or acts of terrorism; 14) any adverse impact on the demand for air travel or our operations from the outbreak of
diseases or epidemic or pandemic outbreaks; 15) our ability to avoid or recover from cyber-based or other security attacks, information technology failures, or other disruptions; 16) returns on pension plan assets and the impact of future discount rate changes on pension obligations; 17) our ability to borrow additional funds or refinance debt, including our ability to obtain the debt to finance the purchase price for our announced acquisition of Asco on favorable terms or at all; 18) competition from commercial aerospace original equipment manufacturers and other aerostructures suppliers; 19) the effect of governmental laws, such as U.S. export control laws and U.S. and foreign anti-bribery laws such as the Foreign Corrupt Practices Act and the United Kingdom Bribery Act, and
environmental laws and agency regulations, both
in the U.S. and abroad; 20) the effect of changes
in tax law, such as the effect of The Tax Cuts and Jobs Act (the «TCJA») that was enacted on December 22, 2017, and changes to the interpretations of or guidance related thereto, and the Company's ability to accurately calculate and estimate the effect of such changes; 21) any reduction
in our credit ratings; 22) our dependence on our suppliers, as well as the cost and availability of raw materials and purchased components; 23) our ability to recruit and retain a critical mass of highly - skilled employees and our relationships with the unions representing many of our employees; 24) spending by the U.S. and other governments on defense; 25) the possibility that our cash flows and our credit facility may not be adequate for our additional capital needs or for payment of interest on, and principal of, our indebtedness; 26) our exposure under our revolving credit facility to higher interest payments should interest rates increase substantially; 27) the effectiveness of any interest rate hedging programs; 28) the effectiveness of our internal control over financial reporting; 29) the outcome or impact of ongoing or future litigation, claims, and regulatory actions; 30) exposure to potential product liability and warranty claims; 31) our ability to effectively assess, manage and integrate acquisitions that we pursue, including our ability to successfully integrate the Asco business and generate synergies and other cost savings; 32) our ability to consummate our announced acquisition of Asco
in a timely matter while avoiding any unexpected costs, charges, expenses, adverse changes to business relationships and other business disruptions for ourselves and Asco as a result of the acquisition; 33) our ability to continue selling certain receivables through our supplier financing program; 34) the risks of doing business internationally, including fluctuations
in foreign current exchange rates, impositions of tariffs or embargoes, compliance with foreign laws, and domestic and foreign government policies; and 35) our ability to complete the proposed accelerated stock repurchase plan, among other things.
Two key components come into play
in coeliac
disease: genes and
environmental factors.
Over the last 50 years CSIRO has saved and will continue to save Australian agriculture billions of dollars
in impacts and reduced
environmental degradation from nationally important emerging infectious
diseases.
Professor Neal has a long - standing research interest
in cardiovascular
disease and diabetes, including the
environmental determinants of high blood pressure and poor cardiovascular health.
The U.S. Centers for
Disease Control and Prevention (CDC) says human exposure to BPA has dropped significantly
in recent years, but some health and
environmental groups believe more needs to be done to get BPA out of consumer products because a wide range of products — such as food storage containers, plastic tableware, and food packaging — are still manufactured with BPA.
Dr. Song has a special interest
in providing integrative care for children with complex medical issues, including autism, ADHD, asthma, autoimmune illness, eczema, failure to thrive, food allergies / sensitivities, reflux, inflammatory bowel
disease and other gastrointestinal disorders, seizures and other neurologic disorders, and
environmental illness.
Dioxin, by far the most toxic of chemicals regulated by the
Environmental Protection Agency, is linked to cancer, birth defects, liver damage, skin
diseases, immune system disorders and changes
in endocrine regulation.
Certainly some of these are involved, as may be excessive processing of foods, drug residues
in foods and water, now - common deficiencies
in DHA and vitamin D, excessive hygiene, lack of challenging childhood
diseases, and likely other nutritional and
environmental causes we have yet to learn of.
Krysia Lynch, Chair Krysia Lynch started her working life as a researcher
in environmental health and epidemiology; researching spatial variations
in disease incidence and health provision.
«We advise families with private wells to have their tap water tested for arsenic,» Dr. Margaret Karagas, senior author and professor at Dartmouth's Children's
Environmental Health and
Disease Prevention Research Center, said
in a press release.
He said most of the
diseases in this part of the world are
environmental related, and keeping the environment clean will keep a lot of sickness and
diseases away.
A coalition including cooling industry representatives and
environmental activist Erin Brockovich called on the state to enforce federal water regulations, regularly test the water supply and improve New York's water infrastructure, as data show the state has the highest number of Legionnaire's
disease cases
in the nation.
In addition, Belinda has many hours of graduate work at the Tulane School of Public Health & Tropical Medicine, with a specialization in International Health, Infectious Disease Control and Environmental Healt
In addition, Belinda has many hours of graduate work at the Tulane School of Public Health & Tropical Medicine, with a specialization
in International Health, Infectious Disease Control and Environmental Healt
in International Health, Infectious
Disease Control and
Environmental Health.
New York Leads the Nation
in Cases of Legionnaires»
Disease The Alliance to Prevent Legionnaires»
Disease Partners with Iconic Public Health and
Environmental Advocate Erin Brockovich and Allergy & Asthma Network to Call for Real Solutions to New York's Growing -LSB-...]
Janet Stout, director of Special Pathogens Laboratory
in Pittsburgh and an associate professor of research at the School of Civil and
Environmental Engineering at the University of Pittsburgh, has studied Legionnaires»
disease for 30 years and called the idea of legislation from the state and the pending City Council legislation «unprecedented.»
The project, first announced by the County Executive
in the fall of 2012, utilizes funding from a two - year grant awarded the state's Center for
Environmental Health by the Agency for Toxic Substances and
Disease Registry, (ATSDR) and was one of only two awarded nationally
in that grant round.
ERIE COUNTY, NY — To increase awareness of childhood lead poisoning prevention, the Erie County Department of Health («ECDOH») along with the Centers for
Disease Control and Prevention, the U.S.
Environmental Protection Agency, and the U.S. Department of Housing and Urban Development, is participating
in National Lead Poisoning Prevention Week (NLPPW) October 20 - 26.
Many
in the Hoosick Falls Central School auditorium viewed the discussion — which included representatives from the
Environmental Protection Agency, Centers for
Disease Control and National Institute of
Environmental Health Sciences — as a way for Gillibrand to grasp the depth of the problem.
In addition, the ECDOH Division of
Environmental Health will have staff from their Rabies,
Disease and Vector Control Program distributing baits via vehicles and on foot.
The press conference also featured Dr. Claressa Lucas of the National Center for Immunization and Respiratory Diseases and Dr. Jasen Kunz of the National Center for
Environmental Health — who will lead the federal Center for
Disease Control team dispatched to assist
in the anti-Legionnaire's effort.
Technological and analytical advances are helping to take
environmental exposures the route of genetic profiles
in predicting a person's
disease risk with greater precision
Earlier research has shown that
environmental factors, including pesticide exposure, may aggravate inherited deficiencies
in mitochondrial function, possibly explaining some cases of Parkinson's
disease.
In September the Centers for
Disease Control and Prevention and the
Environmental Protection Agency issued a joint paper informing the public how to combat these pests.
Environmental health scientist Richard Stahlhut of the University of Rochester Medical Center and his colleagues discovered that even those who had been fasting for 24 hours still had high BPA levels
in their urine, using a U.S. Centers for
Disease Control and Prevention (CDC) survey of 1,469 adults.
«Decreased adiponectin, if it happens
in vivo, appears to be a bad thing and could result
in increased heart
disease,» says
environmental health scientist Richard Stahlhut of the University of Rochester Medical Center, who was not involved
in the research.
Look at the enormous cost of
diseases of
environmental origin
in children — which we've calculated at about $ 55 billion each year for the 4 million babies born
in this country.
In the forefront of battles to eliminate
environmental toxins ever since, the Boston native has helped show the relationship between asbestos, pesticides, and benzene and human
disease.
Some researchers wondered if this tiny island
in the South Pacific had revealed an elusive
environmental trigger for neurodegenerative
disease elsewhere
in the world — the «Rosetta stone» of neurodegeneration.
Modern living produces multi-interactional
environmental pollution but the changes
in human morbidity, including neurological
disease is remarkable and points to
environmental influences.»
The study suggests that dwindling global
environmental biodiversity and worldwide spikes
in infectious
diseases may be linked, said Jason Rohr, associate professor of integrative biology, University of Southern Florida.
Anniston residents with diabetes had much higher PCBs levels
in their bodies — on average 27 percent more — than those who did not have the
disease, according to the study, which was published
in the journal
Environmental Health Perspectives
in May.
A study linking a pesticide
in fish to diabetes adds to the growing chorus of studies suggesting that
environmental contaminants may play a role
in the widespread
disease.
This opens up the possibility for the production and use of sentinel circuits, which produce other bioactive compounds
in response to
environmental or cellular changes, to target a range of
diseases including cancer.»
For instance, alterations
in the composition of the bacterial community are implicated
in the origin of various so - called
environmental diseases.
Modern geographers and cartographers are involved
in diverse projects: tracking fleets of vehicles or products, helping customers locate a Dunkin' Donuts, modeling
environmental scenarios such as oil spills, and studying the spread of
disease.
In the future, some may find work at research institutions,
disease - focused foundations, and
environmental nonprofits, Irion says.
A team of researchers from Simon Fraser University and Culex
Environmental, a Burnaby - based mosquito control company, are studying an invasive,
disease - carrying mosquito, Aedes japonicus, after finding it for the first time
in Western Canada.
«The system could also be adapted for use with other respiratory viruses, and with some modification, for infectious
diseases more broadly,» says lead author Sen Pei, a postdoctoral scientist
in Environmental Health Sciences at Columbia's Mailman School of Public Health.
This can result
in a serious genetic
disease that can cause anemia, neuro - cognitive impairment, and even early death,» says the study's lead - author, Dr. Jean - Louis Guéant, director of the Inserm unit of Nutrition - Genetics -
Environmental Risks at University of Lorraine and head of the Department of Molecular Medicine and Personalized Therapeutics — National Center of Inborn Errors of Metabolism at the University Regional Hospital of Nancy.
«
In some communities it has been a disaster,» said Christopher Portier, director of the U.S. Agency for Toxic Substances and
Disease Registry (ATSDR) and the National Center for
Environmental Health.
The authors contend that the Parkinson's community must come together and focus its activism
in support of: developing a better understand the
environmental, genetic, and behavioral causes and risk factors for Parkinson's to help prevent its onset; increasing access to care — an estimated 40 percent of people with the
disease in both the U.S. and Europe do not see a neurologist and the number is far greater
in developing nations; advocating for increases
in research funding for the
disease; and lowering the cost of treatments — many patients
in low - income countries do not have access to drugs that are both lifesaving and improve quality of life.
Other genetic and
environmental factors, such as pesticide exposure, also play a role
in the
disease.
Because
environmental exposures have not had time to impact IBD progression
in children, researchers have a clearer genetic picture of the
disease allowing them to pick out additional genes overlooked
in adult research, says senior study author Hakon Hakonarson, director of the Center for Applied Genomics at The Children's Hospital of Philadelphia.
«To our knowledge, this is the first documentation of an outbreak of childhood lead poisoning associated with artisanal gold mining,» the team, directed by lead experts from the U.S. Centers for
Disease Control and Prevention, wrote
in the online edition of the journal
Environmental Health Perspectives.
In May, Sen. Robert Casey Jr., D - Pa., wrote to Environmental Protection Agency administrator Lisa Jackson, the Centers for Disease Control and Prevention and state officials, asking them to investigate illness clusters in Pennsylvani
In May, Sen. Robert Casey Jr., D - Pa., wrote to
Environmental Protection Agency administrator Lisa Jackson, the Centers for
Disease Control and Prevention and state officials, asking them to investigate illness clusters
in Pennsylvani
in Pennsylvania.
The incoming AAAS Public Engagement Fellows work
in such varied disciplines as virology, vaccine and pharmaceutical development, public health, demography,
disease ecology,
environmental health, parasitology, and human and veterinary epidemiology.
A study
in rats suggests that exposure to
environmental toxins could be contributing to an inherited vulnerability to common
diseases like breast cancer and high cholesterol.
While Sandia monitors ponds and evaluates resistance to
diseases, PNNL will quantify the biomass production rate of 10 strains of algae that they grow
in a variety of simulated
environmental conditions.
The Children's Health
Environmental Coalition (CHEC) concurs, citing a raft of studies that show how children living
in wood - burning households experience «higher rates of lung inflammation, breathing difficulties, pneumonia, and other respiratory
diseases.»
A protein found
in some animals could lead to a new class of biosensors for detecting
environmental contamination or airborne
disease