Sentences with phrase «in gene expression during»

The team found deep conservation of certain processes that likely reflects similar underlying regulatory processes between mouse and man, but there were also significant differences in gene expression during kidney development, as well as in the timing, scale, organization, and molecular profile of key cell types and cell structures.

Not exact matches

Taylor and colleagues made this discovery by exposing fetal mice to BPA during pregnancy and examining gene expression and DNA in the uteruses of female fetuses.

RNAs contained in this non-coding part act as regulatory molecules and have a large impact on gene expression: where in the body and when during development or adulthood genes are expressed.

Messenger RNA (mRNA) serves as an important intermediary during gene expression, by relating the genetic information of DNA to the molecular mechanisms involved in manufacturing proteins.

«By observing neuronal gene expression in these distinct pathways during development, we detected common patterns, as if an underlying genetic language was bringing them together.»

Enzymes that chemically modify DNA, known as DNA methyltranferases, play critical roles in regulating gene expression during development, but their role in cancer formation is less clear.

This program, resulting in shorter 3 ′ UTRs, is a characteristic of gene expression during immune cell activation and correlates with proliferation across diverse cell types and tissues.

But when the UPR was chemically activated, Bmal1 stayed low during both light and dark phases, which caused a phase shift in the expression of circadian genes.

In aging, this gene expression presumably occurs to compensate for the accumulation of protein damages; during diapause, the same genes may be activated to prepare the whole embryo to catch up with the interrupted development and be ready to hatch as the rainy season starts.

When that lab closed she went back to university, working in a biochemistry and molecular biology lab to study gene expression during wine making, but this contract, too, came to an end.

Several studies had already pinned some of the visible abnormalities in clones on the absence of vital molecules that turn gene expression on and off during fetal development.

The new research focused on just nine genes, those most strongly associated with autism in recent sequencing studies, and investigated their effects using precise maps of gene expression during human brain development.

During development, as an embryo forms differentiated tissues, liver cells, brain cells, muscle cells, the cells in those tissues begin to allow for the selective expression of genes contained in those same 3 billion nucleotides.

«TIA - 1 is known for its ability to regulate gene expression during cellular stress,» says Hewett, who studies the processes that suppress the severe electrical storms in the brain, leading to seizures.

In the new study, a team led by Vanessa Dumeaux during her time at McGill University examined links between gene expression in breast cancer tumors and in the bloodstreaIn the new study, a team led by Vanessa Dumeaux during her time at McGill University examined links between gene expression in breast cancer tumors and in the bloodstreain breast cancer tumors and in the bloodstreain the bloodstream.

«RNA controls splicing during gene expression, further evidence of «RNA world» origin in modern life.»

A study carried out by the Laboratoire Neurobiologie des Interactions Cellulaires et Neurophysiopathologie (CNRS / Aix - Marseille Université), in collaboration with clinicians from Marseilles Public Hospitals (AP - HM) and scientists from the Salk Institute in San Diego (US), has revealed a new gene that plays a crucial role during early development in humans and whose under - expression may induce certain autistic traits.

Another provocative observation from the new study was that transient gene expression events during brain development set up broad distinctions in neural fate between cells in different areas in the cerebral cortex.

Hutchinson - Gilford progeria is caused by a spontaneous mutation during conception in a gene called LMNA, which encodes a protein called prelamin A. Progeria patients experience a buildup of an abnormal version of prelamin A in their cells that, among other changes, distorts the nucleus and alters gene expression.

«We didn't set out to study the relationship between the epigenetic chromatin marks and gene expression during development, but rather to analyze the function of these marks in DNA processing.

Methylation is one type of so - called epigenetic changes, alterations in genes during the lifetime that affect their expression.

For the first time, it is now found by a study that various mechanisms of transcribing DNA into RNA exist during gene expression in the different development phases of zebrafish.

To determine whether shifts in the balance of anterior and posterior field occurred during fin - to - limb evolution, Onimaru, postdoctoral researcher currently at Sharpe's lab (CRG), and his colleagues carefully compared the expression, function and regulation of genes involved in anterior - posterior patterning in pectoral fins of catsharks, with those of mice.

Although we have long known that this signal strongly inhibits protein synthesis in general, during hemoglobin gene expression it first plays its indispensable, positive role before being turned off promptly to allow for massive hemoglobin formation needed for breathing,» said Prof. Raymond Kaempfer, the Dr. Philip M. Marcus Professor of Molecular Biology and Cancer Research at the Hebrew University of Jerusalem.

Researchers at Carnegie Mellon University have developed a new dynamic statistical model to visualize changing patterns in networks, including gene expression during developmental periods of the brain.

The CMU team used PisCES to follow neural gene expressions from conception through adulthood in rhesus monkey brains to find out what genes work together during different points of development.

In particular, they examined what happens during gene expression — when genes copy data from DNA to RNA in order to create proteinIn particular, they examined what happens during gene expression — when genes copy data from DNA to RNA in order to create proteinin order to create proteins.

One is straightforward — during development, cells are assuming their identities and need precise control over protein production, so cells lacking a gene expression regulation mechanism are bound to have defects, particularly in the case of specialized cells like neurons.

«We showed that these genes have unique expression patterns in different brain regions at varying times during brain development.

Increased expression of a gene linked to autism spectrum disorders (ASDs) leads to a remodeling of dendrites during brain development, according to a new study conducted in cultured neurons and an ASD mouse model published in JNeurosci.

Deaf1 isoforms control the expression of genes encoding peripheral tissue antigens in the pancreatic lymph nodes during type 1 diabetes.

Along this line, our primary research goals are directed towards understanding how noncoding RNAs and their RNA - binding proteins are integrated in to the regulation of gene expression and modulation of the host immune response during ¿ - herpesviral infection.

We notably follow the time course of structural changes in response to cues that affect gene expression either transiently or permanently: changes in genome structure during transient hormonal response of differentiated cells and stable trans - differentiation of B cells to macrophages.

Dr. Saptarsi Haldar's research focuses on how cells in the cardiovascular system control gene expression and how these gene control mechanisms go awry during disease.

Along this line, our primary research goals are directed towards understanding how noncoding RNAs and their RNA - binding proteins are integrated in to the regulation of gene expression and modulation of the host immune response during gammaherpesvirus infection.

Current projects are investigating: 1) the expression of inflammatory genes during ischemia and reperfusion of kidneys during urology transplantation and in mouse models; 2) the expression of inflammatory genes and proteins in urine as markers indicating the presence of rejection in renal allografts; and 3) the role of adhesion molecules and chemokines in directing leukocyte infiltration into organ allografts.

Highly Synchronized Expression of Lineage - Specific Genes during In Vitro Hepatic Differentiation of Human Pluripotent Stem Cell Lines.

Exposing S. pistillata to seawater with an elevated calcium concentration resulted in up - regulation of gene expression during the day relative to the night.

Bethesda, USA (2016 - present) Research areas: Super-resolution microscopy, single - molecule imaging, gene expression, computational modeling and data analysis This section includes all projects during my postdoctoral research stay at the National Institutes of Health in Bethesda, MD (Unites States): (9) Understanding gene expression in eukaryotic cells»

The galaxin gene has displayed a high relative expression during midday (relative expression of 59.76 ± 0.89 at 11:00, C11 in Fig. 5A) with statistically significant of p < 0.0005 (one - way ANOVA).

However, there was no difference in the relative expression of the gene during the night - time (C23 and T23 in Fig. 5C).

During specification of SM identity, bd1 mRNA accumulates in a boundary region between the indeterminate meristem and differentiating lateral organ, where it is predicted to suppress ectopic expression of other meristem identity genes in the SM.

The Wnt and TGF - β signaling pathways were identified in the gene expression analysis as being up - regulated during the day (Fig. 4).

A careful examination of tassel development in the maize BR mutants, and evaluation of gene expression patterns during BR loss and GA supplementation, may help shed light on links between these two systems.

In addition to hinting at a link between depression and brain gene expression during development, there was also evidence of overlap between the genetic basis of depression and other mental illnesses.

In the second crucial step, they experimented with dozens of proteins known to control gene expression, especially during the formative process of embryo growth.

In collaboration with Margarita Salas (CBM - CSIC), in bacteriophage φ29 we examine the transcriptional regulator p4 that functions as a switch between early and late gene expression during the infection cyclIn collaboration with Margarita Salas (CBM - CSIC), in bacteriophage φ29 we examine the transcriptional regulator p4 that functions as a switch between early and late gene expression during the infection cyclin bacteriophage φ29 we examine the transcriptional regulator p4 that functions as a switch between early and late gene expression during the infection cycle.

Adaptive changes in adipocyte gene expression differ in AKR / J and SWR / J mice during diet induced obesity.

Changes in gene expression as a response to death, and during subsequent post-mortem ischemia, might be expected to reflect stochastic variation resulting from the enzymatic processes underlying mRNA degradation.

Adaptive changes in adipocyte gene expression differ in AKR / J and SWR / J mice during diet - induced obesity.