The difference between a human being and a chimp is
in gene expression in the epigenome.
Clostridium botulinum produces a transcription factor that can aggregate and self - propagate a prion - like form, leading to genome - wide changes
in gene expression in E. coli, according to a study.
Single - cell RNA - sequencing (scRNA - seq) allows studying heterogeneity
in gene expression in large cell populations.
Paternally inherited Dp / + (patDp / +) mice showed expected increases
in the gene expression in bone, normal postnatal growth and body weight acquisition compared to the littermate controls.
We compared the transcriptomes from VNO and OM of both male and female mice to assess whether differences
in gene expression in these tissues could underpin sexually dimorphic behaviors [17].
These reporters will give us the ability to sort infected cultures to analyze changes
in gene expression in directly infected cells and bystander cells and compare to uninfected cells.
Additionally, the interpretation of levels of change
in gene expression in isolation, without the additional statistical rigor provided by the concomitant analysis of ontological interaction networks, may severely limit critical insights into relevant biologic processes.
This is not a very conceptually satisfying situation and does little to advance our understanding of the mechanism (s) underlying the changes
in gene expression in response to the perturbation or its implications for clinical phenotype.
Susana Zanello, Universities Space Research Association scientist at NASA's Johnson Space Center in Houston, examined eye tissue for changes
in gene expression in the retina — the sensory tissue at the back of the eye.
To see what genes might be involved in this increased aggression, the team used microarrays to look for differences
in gene expression in fly brains.
A baseline study shows major differences
in gene expression in the hypothalamus and pituitary between male and female pigeons.
He has been studying differences
in gene expression in infected and uninfected plants and finds that the fungus seems to increase the activity of genes involved in seed production.
For instance, protein and DNA modifications involved
in gene expression in kidneys must at some point be turned off.
That work revealed that after mating, seminal fluid proteins passed from males to females led to changes
in gene expression in females and led females to increase egg production, reduce feeding and decrease their likelihood to mate again.
They found similar changes
in gene expression in the same genes with increased activity of glucose transporters in both the stem cells and the fat cells, Sen noted.
They compared changes
in gene expression in 37 of them who developed suicidal feelings with previously published work and with post-mortem samples of 26 men who had killed themselves.
Not exact matches
Our study
in an animal model found that influenza infection leads to an increase
in the
expression of muscle - degrading
genes and a decrease
in expression of muscle - building
genes in skeletal muscles
in the legs.
There's better communication,» she told Inc.com
in an interview, citing science that shows meditation changes the brain, immune system, and even
gene expression.
Alnylam has been developing drugs that target
gene expression in order to prevent to production of certain biological material which can cause devastating diseases.
In the clearest possible case, the ANT - OAR cell would differ from a zygote on all of the parameters noted above: The ANT - OAR cell would have a pattern of
gene expression that is clearly distinct from a zygote; it would generate a homogeneous population of cells rather than multiple cell types; it would undergo simple cleavage divisions and not produce any multicellular structures.
Either activating or blocking the
expression of a
gene in the cloning procedure
in order to prevent the development of a zygote might sound like a moral advance.
The net effect of both the assumptions and the conclusion is that some boys are born into situations
in which the combination of
gene expression and social context heavily determine what kind of person they will be.
This dataset contains millions of genomic sequences from a diverse set of rice varieties that, when combined with phenotyping observations,
gene expression, and other information, provides an important step
in establishing
gene - trait associations, building predictive models, and applying these models to breeding.
Because epigenetics is the real driver of your health status, and diet plays a major role
in gene expression (aka epigenetics), at least
in this post's animal study!
Often, the
genes of the new are present
in the body of the old — they are the ideas, the social movements, the fair food networks that start life on the innovative edge, the social fringe, and move towards the middle where they give
expression to the new systems that grows out of the old.
Moshe Szyf, a molecular biologist at McGill University, discusses the way parental licking and grooming affects the
expression of certain
genes in rat pups.
Neuroscientists have over the past decade uncovered evidence, both
in rodent and human studies, that parental caregiving, especially
in moments of stress, affects children's development not only on the level of hormones and brain chemicals, but even more deeply, on the level of
gene expression.
The good news is that little tweaks
in your diet, like adding foods that are high
in long - chain omega - 3 fats, can change the
expression of your
genes.
Maternal care,
gene expression, and the transmission of individual differences
in stress reactivity across generations.
The recent Lancet Breastfeeding Series refers to new discoveries being made about breastmilk — such as its role
in gene expression — so it can be expected that Nestle will use the strategy of launching «new improved» formulas that are «closer to breastmilk» for decades to come (Nestle is currently investing heavily
in epigentics research).
This can lead to change
in baby's physiology and
gene expression.
Our conference for 2018 is packed full of fascinating topics such as the antibacterial properties of human milk carbohydrates, breastmilk as a communication and
gene expression tool, management of chronic breast pain, the physiology of the milk ejection reflex, collaboration
in high conflict settings, and so much more!
Following this
in 2015, an article (Alsaweed et al.) described over 300 novel milk microRNA molecules, components that are known to play a key role
in the regulation of
gene expression.
They examined whether there were differences
in the composition of the breast milks» microRNAs, snippets of RNA that affect
gene expression and can be passed to the infant.
Secretory antibodies
in breast milk promote long - term intestinal homeostasis by regulating the gut microbiota and host
gene expression
Gene Expression in Cumulus Cells and Correlation with Pregnancy Outcome
in Women.
Maternal melatonin effects on clock
gene expression in a nonhuman primate fetus.
Taylor and colleagues made this discovery by exposing fetal mice to BPA during pregnancy and examining
gene expression and DNA
in the uteruses of female fetuses.
Therefore, we questioned whether PTPRF
gene expression might be elevated
in Mature Group 2 samples, as PTPRF overexpression could be causing excessive downward modulation of the insulin signaling pathway
in the women with lower insulin sensitivity.
Therefore, variation
in RNA quality across lactation stage must be considered when interpreting
gene expression results across postpartum time points.
Entitled Social science and epigenetics: opportunities and challenges, the symposium will seek to examine how multidisciplinary research into epigenetics — the science of the lasting marks that modify the
expression of the
genes encoded
in our DNA — might help provide answers to societal concerns including why deprivation has such a marked impact on child development and on health outcomes.
A new study
in Biological Psychiatry found that heroin use is associated with excessive histone acetylation, an epigenetic process that regulates
gene expression.
The DNA segments that carry genetic information are called
genes, but other DNA sequences have structural purposes, or are involved
in regulating the
expression of genetic information.
However, the impact of the two methylation - regulating enzymes was still seen at 10 to 15 months, when scientists found decreased
expression of hundreds of
genes — many of which are key tumor suppressor
genes such as BMP3, SFRP2 and GATA4 —
in the smoke - exposed cells and a five - or - more-fold increase
in the signaling of the KRAS oncogene that is known to be mutated
in smoking - related lung cancers.
Sebat's team was especially interested
in the parts of noncoding DNA that regulate
gene expression.
Utilizing this very sensitive technique they were able to demonstrate significant changes
in the
expression of over 4000
genes.
In subsequent analyses, striking losses in gene expression were observed in genomic regions that had become increasingly methylated with age, whereas regions that had become less methylated showed increases in gene expressio
In subsequent analyses, striking losses
in gene expression were observed in genomic regions that had become increasingly methylated with age, whereas regions that had become less methylated showed increases in gene expressio
in gene expression were observed
in genomic regions that had become increasingly methylated with age, whereas regions that had become less methylated showed increases in gene expressio
in genomic regions that had become increasingly methylated with age, whereas regions that had become less methylated showed increases
in gene expressio
in gene expression.
This study built on previous research from the Sundrud lab, which showed that when TH17 cells entered the intestine
in human tissue samples, they increased the
expression of a
gene called MDR1.
Other labs have used DNA microarray analysis to characterize
gene expression changes
in this model.
When the authors tested the ability of the lizard and snake versions of this limb - genital enhancer to function
in mice, they found that the lizard version was capable of driving
gene expression in the legs and the genitalia (much like the mouse version), while the snake version was only capable of driving
gene expression in the genitalia.