Sentences with phrase «in gene expression in»

The difference between a human being and a chimp is in gene expression in the epigenome.
Clostridium botulinum produces a transcription factor that can aggregate and self - propagate a prion - like form, leading to genome - wide changes in gene expression in E. coli, according to a study.
Single - cell RNA - sequencing (scRNA - seq) allows studying heterogeneity in gene expression in large cell populations.
Paternally inherited Dp / + (patDp / +) mice showed expected increases in the gene expression in bone, normal postnatal growth and body weight acquisition compared to the littermate controls.
We compared the transcriptomes from VNO and OM of both male and female mice to assess whether differences in gene expression in these tissues could underpin sexually dimorphic behaviors [17].
These reporters will give us the ability to sort infected cultures to analyze changes in gene expression in directly infected cells and bystander cells and compare to uninfected cells.
Additionally, the interpretation of levels of change in gene expression in isolation, without the additional statistical rigor provided by the concomitant analysis of ontological interaction networks, may severely limit critical insights into relevant biologic processes.
This is not a very conceptually satisfying situation and does little to advance our understanding of the mechanism (s) underlying the changes in gene expression in response to the perturbation or its implications for clinical phenotype.
Susana Zanello, Universities Space Research Association scientist at NASA's Johnson Space Center in Houston, examined eye tissue for changes in gene expression in the retina — the sensory tissue at the back of the eye.
To see what genes might be involved in this increased aggression, the team used microarrays to look for differences in gene expression in fly brains.
A baseline study shows major differences in gene expression in the hypothalamus and pituitary between male and female pigeons.
He has been studying differences in gene expression in infected and uninfected plants and finds that the fungus seems to increase the activity of genes involved in seed production.
For instance, protein and DNA modifications involved in gene expression in kidneys must at some point be turned off.
That work revealed that after mating, seminal fluid proteins passed from males to females led to changes in gene expression in females and led females to increase egg production, reduce feeding and decrease their likelihood to mate again.
They found similar changes in gene expression in the same genes with increased activity of glucose transporters in both the stem cells and the fat cells, Sen noted.
They compared changes in gene expression in 37 of them who developed suicidal feelings with previously published work and with post-mortem samples of 26 men who had killed themselves.

Not exact matches

Our study in an animal model found that influenza infection leads to an increase in the expression of muscle - degrading genes and a decrease in expression of muscle - building genes in skeletal muscles in the legs.
There's better communication,» she told Inc.com in an interview, citing science that shows meditation changes the brain, immune system, and even gene expression.
Alnylam has been developing drugs that target gene expression in order to prevent to production of certain biological material which can cause devastating diseases.
In the clearest possible case, the ANT - OAR cell would differ from a zygote on all of the parameters noted above: The ANT - OAR cell would have a pattern of gene expression that is clearly distinct from a zygote; it would generate a homogeneous population of cells rather than multiple cell types; it would undergo simple cleavage divisions and not produce any multicellular structures.
Either activating or blocking the expression of a gene in the cloning procedure in order to prevent the development of a zygote might sound like a moral advance.
The net effect of both the assumptions and the conclusion is that some boys are born into situations in which the combination of gene expression and social context heavily determine what kind of person they will be.
This dataset contains millions of genomic sequences from a diverse set of rice varieties that, when combined with phenotyping observations, gene expression, and other information, provides an important step in establishing gene - trait associations, building predictive models, and applying these models to breeding.
Because epigenetics is the real driver of your health status, and diet plays a major role in gene expression (aka epigenetics), at least in this post's animal study!
Often, the genes of the new are present in the body of the old — they are the ideas, the social movements, the fair food networks that start life on the innovative edge, the social fringe, and move towards the middle where they give expression to the new systems that grows out of the old.
Moshe Szyf, a molecular biologist at McGill University, discusses the way parental licking and grooming affects the expression of certain genes in rat pups.
Neuroscientists have over the past decade uncovered evidence, both in rodent and human studies, that parental caregiving, especially in moments of stress, affects children's development not only on the level of hormones and brain chemicals, but even more deeply, on the level of gene expression.
The good news is that little tweaks in your diet, like adding foods that are high in long - chain omega - 3 fats, can change the expression of your genes.
Maternal care, gene expression, and the transmission of individual differences in stress reactivity across generations.
The recent Lancet Breastfeeding Series refers to new discoveries being made about breastmilk — such as its role in gene expression — so it can be expected that Nestle will use the strategy of launching «new improved» formulas that are «closer to breastmilk» for decades to come (Nestle is currently investing heavily in epigentics research).
This can lead to change in baby's physiology and gene expression.
Our conference for 2018 is packed full of fascinating topics such as the antibacterial properties of human milk carbohydrates, breastmilk as a communication and gene expression tool, management of chronic breast pain, the physiology of the milk ejection reflex, collaboration in high conflict settings, and so much more!
Following this in 2015, an article (Alsaweed et al.) described over 300 novel milk microRNA molecules, components that are known to play a key role in the regulation of gene expression.
They examined whether there were differences in the composition of the breast milks» microRNAs, snippets of RNA that affect gene expression and can be passed to the infant.
Secretory antibodies in breast milk promote long - term intestinal homeostasis by regulating the gut microbiota and host gene expression
Gene Expression in Cumulus Cells and Correlation with Pregnancy Outcome in Women.
Maternal melatonin effects on clock gene expression in a nonhuman primate fetus.
Taylor and colleagues made this discovery by exposing fetal mice to BPA during pregnancy and examining gene expression and DNA in the uteruses of female fetuses.
Therefore, we questioned whether PTPRF gene expression might be elevated in Mature Group 2 samples, as PTPRF overexpression could be causing excessive downward modulation of the insulin signaling pathway in the women with lower insulin sensitivity.
Therefore, variation in RNA quality across lactation stage must be considered when interpreting gene expression results across postpartum time points.
Entitled Social science and epigenetics: opportunities and challenges, the symposium will seek to examine how multidisciplinary research into epigenetics — the science of the lasting marks that modify the expression of the genes encoded in our DNA — might help provide answers to societal concerns including why deprivation has such a marked impact on child development and on health outcomes.
A new study in Biological Psychiatry found that heroin use is associated with excessive histone acetylation, an epigenetic process that regulates gene expression.
The DNA segments that carry genetic information are called genes, but other DNA sequences have structural purposes, or are involved in regulating the expression of genetic information.
However, the impact of the two methylation - regulating enzymes was still seen at 10 to 15 months, when scientists found decreased expression of hundreds of genes — many of which are key tumor suppressor genes such as BMP3, SFRP2 and GATA4 — in the smoke - exposed cells and a five - or - more-fold increase in the signaling of the KRAS oncogene that is known to be mutated in smoking - related lung cancers.
Sebat's team was especially interested in the parts of noncoding DNA that regulate gene expression.
Utilizing this very sensitive technique they were able to demonstrate significant changes in the expression of over 4000 genes.
In subsequent analyses, striking losses in gene expression were observed in genomic regions that had become increasingly methylated with age, whereas regions that had become less methylated showed increases in gene expressioIn subsequent analyses, striking losses in gene expression were observed in genomic regions that had become increasingly methylated with age, whereas regions that had become less methylated showed increases in gene expressioin gene expression were observed in genomic regions that had become increasingly methylated with age, whereas regions that had become less methylated showed increases in gene expressioin genomic regions that had become increasingly methylated with age, whereas regions that had become less methylated showed increases in gene expressioin gene expression.
This study built on previous research from the Sundrud lab, which showed that when TH17 cells entered the intestine in human tissue samples, they increased the expression of a gene called MDR1.
Other labs have used DNA microarray analysis to characterize gene expression changes in this model.
When the authors tested the ability of the lizard and snake versions of this limb - genital enhancer to function in mice, they found that the lizard version was capable of driving gene expression in the legs and the genitalia (much like the mouse version), while the snake version was only capable of driving gene expression in the genitalia.
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