Sentences with phrase «in gene expression over»

This is just the first of a series of similar studies, said Gilad, that will look at changes in gene expression over evolutionary time.

In this case, the study authors say, differences in gene expression over the course of a day may cause a person's heart to heal more quickly in the afternoon than in the morning.

Not exact matches

Neuroscientists have over the past decade uncovered evidence, both in rodent and human studies, that parental caregiving, especially in moments of stress, affects children's development not only on the level of hormones and brain chemicals, but even more deeply, on the level of gene expression.

Following this in 2015, an article (Alsaweed et al.) described over 300 novel milk microRNA molecules, components that are known to play a key role in the regulation of gene expression.

Utilizing this very sensitive technique they were able to demonstrate significant changes in the expression of over 4000 genes.

Prasher and Chalfie were awarded a patent for the use of GFP as a marker of gene expression; in total, it earned Prasher just a few hundred thousand dollars in royalties over 15 years.

The trick is to run the tape of evolution over again: to intervene in the development of a chicken embryo, for instance, to reverse evolution, rolling back the clock to manifest earlier patterns of gene expression.

This magic spot was later identified as ppGpp and shown to influence the expression of over 500 genes in response to stress.

Its appearance following starvation and other stresses is associated with changes in the expression of over 500 genes, most prominently genes for the structural RNAs that are components of the ribosome — the enzyme responsible for protein synthesis.

The Lazar lab has been working on HDAC3 for over a decade, focusing on the pivotal role of this enzyme in hormone - mediated regulation of gene expression and metabolism.

Additionally, researchers found that nearly 300 genes showed variation in their expression in heart tissue over the course of a day — a possible basis for the tissue's change in behavior.

The study used novel gene expression methods that allowed the researchers to identify over one thousand genes that are involved in the regeneration process of individual stentor cells.

The study was also the first to study gene expression in children over the course of their allergic reactions, allowing each subject's reaction to be compared to their own pre-reaction state, rather than to a control group without peanut allergies.

Based on analyses of over 600 drug and breast cancer cell pairings, researchers showed that, for some cells, drug exposure can cause significant changes in gene expression — indicating the successful action of a drug on its target — without affecting cell growth or survival.

Gene expression patterns in the hippocampus samples were examined using DNA microarrays that measured the expression levels of over 30,000 genes (transcripts) per sample.

One is straightforward — during development, cells are assuming their identities and need precise control over protein production, so cells lacking a gene expression regulation mechanism are bound to have defects, particularly in the case of specialized cells like neurons.

We measured gene expression of Cry1, Cry2 and Cry4 in the retina, muscle and brain of zebra finches over the circadian day to assess whether they showed any circadian rhythmicity.

In addition to a range of antibodies, Abcam offers over 4,000 pharmacological tools covering receptor agonists and antagonists, like Tamoxifen Citrate and oestrogen receptor, which is also used in the control of gene expressioIn addition to a range of antibodies, Abcam offers over 4,000 pharmacological tools covering receptor agonists and antagonists, like Tamoxifen Citrate and oestrogen receptor, which is also used in the control of gene expressioin the control of gene expression.

A novel way of approaching protection - based therapeutics for glaucoma should derive from evidence accumulating over two decades in stroke and cardiac arrest: That simultaneously activating a variety of self - defense responses in cells with stressful «conditioning» stimuli induces the expression of a host of genes that promote cell survival.

The study used novel gene expression methods that allowed the researchers to identify over one thousand genes involved in the regeneration process of individual stentor cells.

By surveying gene expression in over 53,000 cells from the small intestine, researchers have created a rich reference for understanding the biology of inflammatory bowel disease and food allergies, among other conditions.

Wahl, a professor in Salk's Gene Expression Laboratory, will receive $ 7.9 million over a seven - year period to further his cancer research.

Gene expression differences over a critical period of afferent - dependent neuron survival in the mouse auditory brainstem.

We find that many genes change expression over relatively short PMIs in a tissue - specific manner, but this potentially confounding effect in a biological analysis can be minimized by taking into account appropriate covariates.

Our first striking observation was that over one half of measured genes are affected by common genetic variation in human populations — called expression quantitative trait loci or eQTLs.

In virtually all viral expression systems employed by scientists, non-essential components are stripped away and the remaining native genes are spread over multiple plasmids to ensure safety.

Coordinated gene expression between Trichodesmium and its microbiome over day — night cycles in the North Pacific Subtropical Gyre — Kyle R Frischkorn — The ISME Journal

The greatest changes in gene expression were seen when the V − S − and V+S − fractions were compared (Figure 4B) with over a thousand genes changing in each direction.

The mean FPKM expression values are shown for all the VR and formyl peptide receptors (FPR) genes in the OM; error bars represent the standard error over the mean from the six biological replicates.

We find evidence of expression for all VR, and almost all OR genes that are annotated as functional in the reference genome, and use the data to generate over 1100 new, multi-exonic, significantly extended receptor gene annotations.

The mean FPKM expression values are shown for all the OR genes and trace amine - associated receptor (TAAR) genes in the VNO; error bars represent the standard error over the mean from the six biological replicates.

Towards this goal, we mined the genomics data to identify sets of genes, the expression of which performed in the same way over the entire spectrum of experimental conditions.

Over the next decade, he authored key papers predicting the number of genetic markers required for GWAS in humans, and pioneered the field of genetics of global gene expression (eQTL analysis).

Over time, the repair system in the cell works worse, and much of this damage either is not corrected at all, disrupting the expression of genes, or converted into mutations.

DNA methylation could play an important role in mediating the effects of DR because it is sensitive to the effects of nutrition and can affect gene expression memory over time.

Expression trends of specific genes related to muco - ciliary function and airway restitution as compared with smoking status and lung cancer: TFF3, CABYR, and MUC5AC are over expressed in current smokers with lowered expression in both former and neveExpression trends of specific genes related to muco - ciliary function and airway restitution as compared with smoking status and lung cancer: TFF3, CABYR, and MUC5AC are over expressed in current smokers with lowered expression in both former and neveexpression in both former and never smokers.