Sentences with phrase «in gene regulation»

Are behavioral differences primarily due to changes in gene regulation or structure?

During her studies, she was interested in gene regulation and its impact on particular diseases, focusing on cancer.

The focus thereby was on microRNA — a short, single - stranded RNA molecule that is now recognised as playing an important role in gene regulation.

The Marsh - Armstrong laboratory studies molecular mechanisms involved in gene regulation, development and disease of the central nervous system, focusing principally on the retina.

Major Symposium A: Transcriptional Control of Immunity: Diverse Regulatory Mechanisms in Gene Regulation Ballroom D Chairs: Amy S. Weinmann, Univ. of Alabama, Birmingham Boris Reizis, New York Univ..

Ornish took biopsies before and after the dietary change, and you can see the subtle shift in gene regulation from more red to more green.

This methyl group is normally used in a gene regulation process called epigenetic histone methylation.

In addition, he said, «The broader questions in gene regulation and signal transduction are also fundamental to immunity.»

These changes in gene regulation differed from those of mice or rats under the same conditions, the researchers found.

SpDamID also is uniquely able to identify DNA bound by more than one protein, often a critical step in gene regulation.

Many researchers were hunting for intrinsic impairments in gene regulation with aging.

D. student in the UW School of Medicine and Public Health, revealed key differences in gene regulation in conventionally raised mice and mice raised in a germ - free environment.

Major Symposium A: Transcriptional Control of Immunity: Diverse Regulatory Mechanisms in Gene Regulation Chairs: Amy S. Weinmann, Univ. of Alabama, Birmingham Boris Reizis, New York Univ..

He joined the Dimitris Thanos lab «at the perfect time,» when a growing appreciation of the importance of chromatin in gene regulation presented many opportunities for the ambitious and eager young scientist.

Even autosomes display divergent expression patterns in gene regulation either mediated through hormones or directly modulated by sex chromosomes.

Three Scientific Programs provide focus in Gene Regulation & Cell Proliferation, Signal Transduction, and Cancer Genetics.

Knowledge on these demethylases has led to a tremendous progress in the understanding of methyl marks in gene regulation and role in numerous diseases.

Throughout the 2000s, Wistar scientists made seminal discoveries in the field of epigenetics and RNA transcription, contributing new knowledge on the role of histone modifications in gene regulation and DNA repair and how different RNA species, including microRNAs (miRNA) and long noncoding RNAs (lncRNA), are generated and how they regulate gene transcription.

** microRNAs (miRNAs) are noncoding RNAs which play an important role in gene regulation and in particular in the inactivation of genes.

The experiments have been carried out using Xenopus laevis oocytes, an animal model used by the laboratory to study fundamental processes involved in gene regulation.

Laboratory experiments show that microplastics can have negative impacts on organisms, such as a reduction in the growth of marine worms and changes in gene regulation in fish.

Moving from biochemistry to molecular biology, Palatnik started investigating the role of microRNAs — tiny RNA molecules that are important in gene regulation in most life forms — in the development of the plant Arabidopsis.

In the grand scheme the differences between the two creatures are just adjustments to a basic body plan, and such adjustments, we are assured by evo devo, are the result of changes in gene regulation, not a complete new suite of genes.

Today, a team of researchers from the University of Geneva (UNIGE), Switzerland, led by Emmanouil Dermitzakis, Louis - Jeantet Professor at the Faculty of Medicine, reveals that this is not always the case and that DNA methylation may play both a passive and active role in gene regulation.

After having conducted a large - scale study performed on cells from the umbilical cords of 204 newborns, the researchers from UNIGE demonstrate that DNA methylation may play both a passive and active role in gene regulation.

All this means the truffle has a very unique pattern of DNA methylation which may play a role in the gene regulation.»

Ferran Azorín, head of the «Chromatin structure and function» group says, «although previous data pointed to the possibility of ubiquitin receptors also contribute to cell processes, data were scarce and a direct role in gene regulation had not been demonstrated.»

In gene regulation, this means that when X activates Y, X and Y both can activate Z.

«But they are the first empirical demonstration in higher primates that evolution may often work through changes in gene regulation.»

Since they were first discovered in 1993, there had been growing interest in microRNAs and their role in gene regulation.

MicroRNAs are tiny RNA molecules that have very important roles in gene regulation.

Chd1 (chromodomain - helicase - DNA - binding protein 1) was suspected since its discovery in 1993 to play a role in gene regulation (Delmas et al., 1993).

In the article describing the work in Molecular Therapy, co-authors Charis Himeda, Takako Jones and Peter Jones highlight the important implications for similar types of genetic diseases: «With increasing evidence that the repeat genome (comprising nearly half the human genome) plays important roles in gene regulation, additional diseases will likely be found associated with aberrant repetitive genomic sequences,» they write.

«In addition to lending support to the idea that changes in gene regulation are a key part of our evolutionary history, these new results help to define exactly which regulatory factors may be important, at least in certain tissues.

The vast differences between humans and chimpanzees are due more to changes in gene regulation than differences in individual genes themselves, researchers from Yale, the University of Chicago, and the Hall Institute in Parkville, Victoria, Australia, argue in the March 9, 2006, issue of the journal Nature.

A major part of the Panne lab focuses on chromatin and its role in gene regulation.

The tool identifies genomic variations located in non-coding DNA that may be involved in gene regulation.

Over the years his research has focused on chromatin structure, its modifications and their role in gene regulation, and he has partnered to publish, in his career, over 153 papers.