Sentences with phrase «in genes responsible»

Much of our knowledge of leptin comes from the study of two brands of lab mouse: the ob / ob mouse, deficient in genes responsible for leptin production; and the db / db mouse, deficient in the leptin receptor gene.

The condition is caused by mutations in the genes responsible for muscle structure and functions.

The men most likely to benefit could be identified by genetic testing to look for mutations in genes responsible for DNA repair — including the BRCA genes and the gene ATM.

The most common, found in nearly two - thirds of the samples, were abnormalities in genes responsible for the androgen receptor — a cell structure that sends growth signals in response to the male hormone androgen.

The article also points out that the epitranscriptome could be altered in some human diseases, while alterations in genes responsible for cancer are also being discovered.

Researchers from several institutions, including, UCLA, Boston University, Stanford University and the Institute for Aging Research at Hebrew SeniorLife, analyzed blood samples from nearly 10,000 people to find that genetic markers in the gene responsible for keeping telomeres (tips of chromosomes) youthfully longer, did not translate into a younger biologic age as measured by changes in proteins coating the DNA.

If the silencing occurred in a gene responsible for suppressing tumor formation, the result would appear the same as genetic mutations that predispose people to cancer.

It was in the gene responsible for the 2A receptor that the researchers found the only marker significantly associated with response to the drug.

However, they were able to determine that there were significant differences in the gene responsible for that enzyme between dogs and wolves.

Not exact matches

The treatment (which involves injecting people with modified viruses carrying the CRISPR technology that will go in and repair the faulty DNA) can be injected directly into the retina and, in this case, used to delete the portion of the CEP290 gene that's responsible for the disease.

Patients that have a defective gene called RPE65 — which is responsible for producing a protein that makes light receptors in the eye — suffer from leber congenital amaurosis and retinitis pigmentosa, yet now have hope.

Scientists have figured out the specific gene mutation responsible for red hair — and why it's more common in beards than on heads.

The ability to locate the individual gene or gene sequence responsible for each disease could revolutionize biomedicine in the 21st century.

Actually, science is continually showing us that while no one gene is defined as being responsible for a man or woman being attracted to their own gender, the complex reasoning behind it, much like many other parts of being a human being, is in fact based in genetics, in the physical.

Los Baños, Philippines — The version of the gene primarily responsible for the aroma in Thai Jasmine rice is found...

Researchers have discovered that the gene responsible for producing capsaicin, the chemical that makes chile peppers hot, appears in tomatoes...

She is identifying the enzymes in these natural products to find the genes responsible so that they can be introduced into other plants.

When similar analysis was performed on the db mice, it was found that the disrupted db gene was responsible for encoding a protein that functions as a leptin receptor: When it binds circulating leptin at the cell surface, it sets in motion a biochemical cascade inside the cell.

The genes responsible for making psilocybin appear to have been exchanged in an environment with a lot of fungus - eating insects, namely animal manure.

The genes responsible for these proteins undergo frequent point mutations, resulting in genetic «drift»; moreover, the genes from different animal and human strains may also interchange, resulting in genetic «shift.»

Researchers pin down two genes that may be responsible for abnormal neural development in Down's mice embryos.

A new meta - analysis suggests that low expression levels of 10 related gene sets responsible for mitochondrial machinery play an important role in this disorder — all previously unlinked to Parkinson's.

According to studies, approximately one out of every 40 individuals in the United States is a carrier of the gene responsible for spinal muscular atrophy (SMA), a neurodegenerative disease that causes muscles to weaken over time.

Although a team led by Mahajan identified the gene responsible for the disease in 2012, a cure has yet to be developed.

Patrick Forterre of the University of Paris - Sud has also analyzed enzymes responsible for DNA replication and has concluded that the genes for such enzymes in eukaryotes probably have a viral origin.

Yet, in this plant (as well as in certain conifers), the researchers found genes similar to those responsible for the formation of flowers, and which are organized according to the same hierarchy (with the activation of one gene activating the next gene, and so on)!

This, in turn, offers tremendous insight into the genes responsible for producing different morphological forms (or phenotypes).

Ian Baldwin of the Max Planck Institute for Chemical Ecology in Jena, Germany, and colleagues genetically modified petunia plants to silence genes responsible for producing specific scent molecules.

Next, Anderson and his colleagues used a set of genetic tools to identify exactly which neurons were responsible for the effect on aggression and to see if the gene that encodes for Tk also controls aggressive behavior by acting in that cell.

Almost immediately such familial genome sequencing proved its value, uncovering mutations responsible for diseases caused by defects in a single gene.

The researchers caution that this study is only a starting point in the long process of finding the gene or genes directly responsible for longevity because the implicated area of chromosome 4 may hold as many as 500 genes.

«We believe these master genes are responsible for traumatic brain injury adversely triggering changes in many other genes,» said Xia Yang, a senior author of the study and a UCLA associate professor of integrative biology and physiology.

According to recent studies, approximately one out of every 40 individuals in the United States is a carrier of the gene responsible for spinal muscular atrophy (SMA), a neurodegenerative disease that causes muscles to weaken over time.

We found that the gene in nitrate - utilizing soil bacteria, responsible for the destruction of nitrous oxide, can be regulated when copper is added.

They found that the strain had acquired the gene for phospholipase A2, called SlaA, in the mid-1980s, which suggested that SlaA was responsible for the jump in virulence.

The researchers succeeded in identifying the enzyme and gene responsible for the formation of a precursor of TA - G biosynthesis, and so were able to engineer plants with lower TA - G.

Scientists have discovered the first example of a gene solely responsible for an autoimmune disease, a type of disorder in which the immune system attacks the body.

A new report by researchers in the Perelman School of Medicine at the University of Pennsylvania found that loss - of - function mutations to Filaggrin - 2 (FLG2), a gene that creates a protein responsible for retaining moisture and protecting the skin from environmental irritants, were associated with atopic dermatitis in African American children.

Transcription factors are responsible for either inhibiting or promoting the expression of genes, and master regulatory transcription factors are like transcription factors on steroids: their actions regulate thousands of genes in different kinds of cells.

As reported in the title story of Nature Neuroscience's May issue, an international team has now progressed significantly in understanding gene defects responsible for ALS.

The same gene network also plays a role in programming the fly neurons responsible for taste, the researchers report in the journal PLOS Genetics.

Doyle is now tackling a far bigger network of genes in E. coli: the master network responsible for governing its metabolism.

Korenberg was convinced that with Mills» approach of directly measuring the brain's electrical firing they could solve the puzzle of precisely which genes were responsible for building the brain wiring underlying the different reaction to human faces in Williams syndrome.

The results, reported in the July 19 Science, reveal a small cluster of E. lenta genes responsible for nixing digoxin.

«Mutations responsible for cleft palate and related birth defects identified: Study of Amish and Saudi Arabian families finds mutations in HYAL2 gene that impact development.»

Steve: And there's one of the researchers you quote in the article talks about, there may be genes that are not directly responsible for some aspect of brain function even at a biochemical cascade level; there might be a gene that is responsible for the width of the birth canal and that that could be associated with ultimately with intelligence.

Genetics plays a role in athletic performance, but pinpointing which of our genes are responsible is tricky.

In these animals, they switched off the gene responsible for producing the enzyme arylsulfatase G.

But the genetic factors underpinning seed coat permeability remained a mystery until Ma and his team used a map - based cloning approach to hone in on GmHs1 - 1 as the gene responsible for hard seededness.

The disorder runs in families, but the gene responsible had eluded scientists.