Sentences with phrase «in genome analysis»

The CNAG is a young and modern institution that covers a wide range of capabilities in genome analysis and data handling.

To carry out projects in genome analysis that will lead to significant improvements in people's health and quality of life, in collaboration with the Catalan, Spanish, European and International research and clinical community.

In their genome analysis, the researchers discovered that the genetic information of the gibbons differs in their entirety from that of humans and of apes.

Not exact matches

Each individual has thousands of structural variants in their genome, so the researchers narrowed down their analysis to examine just a handful of regulatory regions where genetic variation seemed most likely to cause disruption.

An expanded analysis of colorectal cancer sequences in The Cancer Genome Atlas database showed a high incidence of YME1L1 mutations.

Their analysis of data in previous studies done by The Cancer Genome Atlas group have shown that the types of abnormal methylation levels they found are lower in smokers who have quit for more than 10 years than those who have not quit.

Among individuals with two divergent mitochondrial haplotypes (mt - haplotypes), the genome - wide analyses revealed significant differences in nuclear allele frequencies.

For Chad Nusbaum, co-director of the Genome Sequencing and Analysis program at the Broad Institute of Harvard University and the Massachusetts Institute of Technology (MIT) in Cambridge, the event was a professional milestone.

An analysis of the cat genome led by researchers at Washington University School of Medicine in St. Louis reveals some surprising clues.

The work carried out by Dr Casewell and his co-authors was used in the second paper outlining the analysis of the genome of the Burmese python, also published in the same edition of PNAS.

The analysis revealed that the human genome is organized into large pieces of low or high epigenetic stochasticity, and that these regions correspond to areas of chromosomes that are structurally different in the cell nucleus.

Meta - analyses of genome - wide association studies conducted in these ethnically - diverse populations identified a total of 878 genetic variants belonging to 18 loci associated with asthma risk.

Now with an extensive and diverse collection of representative apple genomes, thorough and careful analyses have allowed Fei's group to distinguish important genetic markers that will greatly aid breeders in their quest for better apples — be it for disease resistance, shelf - life, taste, or even size.

The pitfalls of statistical analysis In the new investigation, Wörheide and his colleagues reanalyzed the genome data reported in the earlier studies, and their results reject the «Ctenophora first» hypothesiIn the new investigation, Wörheide and his colleagues reanalyzed the genome data reported in the earlier studies, and their results reject the «Ctenophora first» hypothesiin the earlier studies, and their results reject the «Ctenophora first» hypothesis.

An analysis of the HPV16 genome from 5,570 human cell and tissue samples revealed that the virus actually consists of thousands of unique genomes, such that infected women living in the same region often have different HPV16 sequences and variable risks to cancer.

Producing a short list of strong candidates was in itself a feat, accomplished by applying the right filters to analysis of human and chimpanzee genomes, said co-author Gregory Wray, professor of biology and director of the Duke Center for Genomic and Computational Biology.

«The molecular analysis allowed us to see where the cocktails were inducing changes in the genome, and to link those changes to the treatment failure,» said co-first author CPT Jeffrey Kugelman, Ph.D., of USAMRIID.

A comparative analysis of the genomes ofDrosophila melanogaster, Caenorhabditis elegans, and Saccharomyces cerevisiae — and the proteins they are predicted to encode — was undertaken in the context of cellular, developmental, and evolutionary processes.

The following Berkeley Lab researchers also contributed to the study: Benjamin Bowen, a member of Northen's lab in EGSB and at the Joint Genome Institute, a DOE Office of Science User Facility, helped analyze metabolomics data; Ulas Karaoz in the Earth and Environmental Sciences Area (EESA) analyzed metagenomics data; and Joel Swenson, a former postdoctoral researcher in Biosciences» Biological Systems and Engineering Division, helped conduct correlation and statistical analyses.

Comprehensive genome analysis: more than 85,000 participants from 35 studies Under the direction of the National Institute of Environmental Health Sciences in the United States, the team of international scientists analyzed the data from a total of 85,170 participants from 35 study cohorts.

Using advanced sequencing technologies, University of Oklahoma anthropologists demonstrate that human DNA can be significantly enriched from dental calculus (calcified dental plaque) enabling the reconstruction of whole mitochondrial genomes for maternal ancestry analysis — an alternative to skeletal remains in ancient DNA investigations of human ancestry.

Human DNA can be significantly enriched from dental calculus (calcified dental plaque) enabling the reconstruction of whole mitochondrial genomes for maternal ancestry analysis — an alternative to skeletal remains in ancient DNA investigations of human ancestry.

Collaborative genome - wide association analysis supports a role for ANK3 and CACNA1C in bipolar disorder

In - depth analysis of the human body's microflora has been possible only in the past few years — a by - product of the same new gene sequencing techniques that have allowed scientists to cheaply and accurately identify the DNA of the human genomIn - depth analysis of the human body's microflora has been possible only in the past few years — a by - product of the same new gene sequencing techniques that have allowed scientists to cheaply and accurately identify the DNA of the human genomin the past few years — a by - product of the same new gene sequencing techniques that have allowed scientists to cheaply and accurately identify the DNA of the human genome.

«Our finding from statistical analyses of all genes in the genome that SMCHD1 was the only plausible site of causal variants for arhinia — lack of a nose — was frankly shocking, since prior to our study no patients had ever been reported with both conditions.»

These genomic variations have been revealed by studies in the population and by analysis of the genomes of colon cancer patients that are available in data bases such as that of the 1000 Genomes Projecgenomes of colon cancer patients that are available in data bases such as that of the 1000 Genomes ProjecGenomes Project Data.

In an analysis of ancient genomes published August 4 in Current Biology, researchers at Stockholm University and Uppsala University in Sweden and Middle East Technical University in Turkey report that at least two waves of early European settlers belonged to the same gene pool as farmers in Central Turkey — genealogy that can be traced back to some of the first people to cultivate crops outside of MesopotamiIn an analysis of ancient genomes published August 4 in Current Biology, researchers at Stockholm University and Uppsala University in Sweden and Middle East Technical University in Turkey report that at least two waves of early European settlers belonged to the same gene pool as farmers in Central Turkey — genealogy that can be traced back to some of the first people to cultivate crops outside of Mesopotamiin Current Biology, researchers at Stockholm University and Uppsala University in Sweden and Middle East Technical University in Turkey report that at least two waves of early European settlers belonged to the same gene pool as farmers in Central Turkey — genealogy that can be traced back to some of the first people to cultivate crops outside of Mesopotamiin Sweden and Middle East Technical University in Turkey report that at least two waves of early European settlers belonged to the same gene pool as farmers in Central Turkey — genealogy that can be traced back to some of the first people to cultivate crops outside of Mesopotamiin Turkey report that at least two waves of early European settlers belonged to the same gene pool as farmers in Central Turkey — genealogy that can be traced back to some of the first people to cultivate crops outside of Mesopotamiin Central Turkey — genealogy that can be traced back to some of the first people to cultivate crops outside of Mesopotamia.

«Gene variants modifying Huntington's symptom onset may lead to new therapeutic strategies: Genome - wide association analysis identifies sites associated with earlier - or later - than - expected symptom appearance in human patients.»

Veeramah is quick to point out Larson's analysis hinged largely on the genome of one ancient pooch, extracted from a 5,000 - year - old fossilized ear bone preserved at a Neolithic site in Ireland called Newgrange.

While several studies in the intervening years have investigated whether particular genes were responsible for modifying HD onset, this is the first to employ genome - wide association (GWA) analysis, which scans an individual's whole genome to identify chromosomal regions containing variants that are associated with the disease traits that are being studied.

Commenting on the survey results, David Lipman, director of the US National Center for Biotechnology Information in Bethesda, Maryland, says that the worries about data handling and analysis were an issue even in the earliest discussions of the genome project.

Before the consortium came together, he had participated in sequencing the genomes of two vocal learners, a songbird and a parrot, but he knew he couldn't do all of the additional sequencing and analysis work that would be required to identify genes related to vocal learning — not by himself, at least — so he teamed up with Genome 10K, a project aiming to collect genomes for 10,000 vertebrate species.

In the February 23, 2015 online edition of Nature Genetics, these researchers describe how the comparative analyses of these genomes allowed them to track the evolution of mycorrhizal fungi.

The genome - wide analyses showed that Cpf1 was highly specific, showing fewer off - target cleavage sites (6 for LbCpf1 and 12 for AsCpf1), compared to Cas9, cleaving at > 90 sites in the human genome (Fig. 1a).

The analysis of the entire genome had several surprises in store for them: The genome resembles more that of a fungi than a microsporidium and, in addition, also has a mitochondrial genome.

The Welcome Trust - funded Sanger Institute, near Cambridge in the UK, carries out large - scale sequencing and analysis to further the knowledge of genomes of different species.

Careful attention to phenotyping diseases, facilitated by our knowledge of the human genome and computational analysis, has allowed observant physicians and physician - scientists to identify and categorize diseases in a manner that has informed basic science, given it new contexts, and in many instances provided important new directions for investigation.

Further analysis showed that the retrovirus was a gammaretrovirus closely linked to MLVs found in mice, though analysis revealed its genome to be slightly — less than 3 percent — different.

A comparative analysis with the cacao tree genome also shows that the biosynthesis of caffeine is due to enzymes unique to each species, which appeared at various moments in their evolution.

A comparative analysis of genomes by the international consortium also revealed that the organisation of the coffee tree genome is best preserved in the Asteridae (the family to which potatoes and tomatoes belong) and is very close to that of the ancestral species from which all true Dicotyledons (or Eudicotyledons) descended through evolution.

In collaboration with various experimental groups worldwide, we concentrate on comparative genome analysis at various levels.

In the second analysis, the team scrutinized the genomes of pregnant women reporting a gradient of nausea and vomiting symptoms, from none to very severe.

New research led by Li Ding, Ph.D., of Washington University School of Medicine in St. Louis, shows that current approaches to genome analysis systematically miss detecting a certain type of complex mutation in cancer patients» tumors.

«De-extinction probability increases with every improvement in ancient DNA analysis,» said Stewart Brand, co-founder of the nonprofit conservation group Revive and Restore, which aims to resurrect vanished species including the passenger pigeon and the woolly mammoth, whose genomes have already been mostly pieced together.

To shed light on how co-infection may affect evolution, Sentandreu sequences parts of the genome of both viruses and analyses genetic variability and adaptive evolution in co-infected patients.

Researchers who participated in the research are: Bru Cormand, Claudio Toma, Bàrbara Torrico and Alba Tristán, from the Department of Genetics and the Institute of Biomedicine of the University of Barcelona (IBUB), affiliated centres with the campus of international excellence BKC; Concepció Arenas (Department of Statistics of the UB) and Mònica Bayés, researcher from the National Centre for Genome Analysis (CNAG), located at the Barcelona Science Park (PCB - UB), and the groups led by Amaia Hervás, coordinator of the Child and Adolescence Mental Health Unit at the Mutua de Terrassa University Hospital, and Marta Maristany, from Sant Joan de Déu University Hospital, affiliated centres with the campus of international excellence HUBc.

Subsequent analysis of two - thirds of the genome in the 2009 A (H1N1) isolated from more than a dozen pigs shows that it closely matches the human version of the virus.

Just as the Human Genome Initiative in the 1990s sequenced human DNA for the subsequent identification and analysis of genes, so too will the Materials Genome Initiative sequence materials for identifying new properties for a variety of applications.

As scientists race to decode genomes — not just of humans but of bacteria, yeast, chimps, dogs, whales and plants — the number of DNA sequences available for analysis has grown 40,000-fold in the past 20 years, providing unprecedented insight into billions of years of species evolution.

On 20 December 2013, a paper by the Amborella Genome Sequencing Project that includes a full description of the analyses performed by the project, as well as implications for flowering plant research, will be published in the journal Science.