Sentences with phrase «in glioma cell»

It was reported, for example, that CSC state could be maintained by overexpressing hypoxia - inducible transcription factor (HIF2α) in glioma cell lines [40].

In a new study published in Scientific Reports, Tokyo Medical and Dental University (TMDU)- led researchers investigated photodynamic detection of cancer stem cells in a glioma cell line, a model of a highly aggressive type of brain cancer.

Gαs went from lipid rafts to nonraft regions of the plasma membrane in the glioma cells, which enhanced its signaling ability.

Not exact matches

A paper he published early this year in the Journal of Clinical Oncology describes a dendritic cell vaccine in advanced glioma, an aggressive form of brain cancer.

And in May, a week after Massachusetts Sen. Edward Kennedy was diagnosed with a glioma, The EMR Policy Institute, a Marshfield, Vt. — based nonprofit organization that supports research on the effects of electromagnetic radiation, released a statement linking his tumor to heavy cell phone use.

There is plenty of anecdotal evidence out there claiming a link between cell phone use and cancer: Keith Black, chairman of neurosurgery at Cedars - Sinai Medical Center in Los Angeles, says that the brain cancer (malignant glioma) that killed O. J. Simpson's attorney, Johnnie Cochran, was the result of frequent cell phone use, based on the fact that the tumor developed on the side of the head against which he held his phone.

When combined with the compound, called ganciclovir, these loaded nanoparticles were 100 percent effective at killing glioma cells grown in laboratory dishes.

Now, Johns Hopkins researchers report they have used nanoparticles to successfully deliver a new therapy to glioma cells in the brains of rats, prolonging their lives.

The results suggest the simultaneous activation of certain molecular pathways — actions among molecules in a cell that can lead to change — in particular the MAPK and PI3K cellular pathways, triggered tumor initiation and produced increasingly dense low - grade gliomas that quickly progressed to glioblastoma multiforme (GBM).

They confirmed low levels of miR - 184 expression in human glioma tissue samples and cultured cell lines as well as an increase in the expression of SND1 compared to normal brain tissue.

«In principle, both these features make GA11 an attractive drug candidate to target glioma stem - like cells in glioblastoma multiforme tumors,» said Ichiro Nakano, M.D., Ph.D., and colleagues in the papeIn principle, both these features make GA11 an attractive drug candidate to target glioma stem - like cells in glioblastoma multiforme tumors,» said Ichiro Nakano, M.D., Ph.D., and colleagues in the papein glioblastoma multiforme tumors,» said Ichiro Nakano, M.D., Ph.D., and colleagues in the papein the paper.

They demonstrated that in the absence of SERT, antidepressants accumulate gradually in the plasma membrane microdomains of glioma cells.

They then conducted biochemical analyses to identify neuroligin - 3, confirm that the protein could stimulate tumor growth in cultured samples of several kinds of human high - grade gliomas and study which signals the protein uses within glioma cells to promote their growth.

Nakano says UAB will be the only site in the Deep South for this unique trial aimed at a molecular target in glioma stem cells, a target that is different from the ones described in the Cancer Research paper.

Monje first became interested in neurons» role supporting tumors while working on childhood glioma, a cancer that strikes in the precursors to glial cells in the developing brain.

In 2015, her lab published a paper in Cell (DOI: 10.1016 / j.cell.2015.04.012) that found that both adult and pediatric glioma cells grew faster when adjacent to highly active neuronIn 2015, her lab published a paper in Cell (DOI: 10.1016 / j.cell.2015.04.012) that found that both adult and pediatric glioma cells grew faster when adjacent to highly active neuronin Cell (DOI: 10.1016 / j.cell.2015.04.012) that found that both adult and pediatric glioma cells grew faster when adjacent to highly active neurons.

The most common primary, malignant brain tumors in adults, called glioma, are formed from cells in the brain that are not nerve cells.

«Conversely, the necrotic part of the tumor is driven by a distinct set of glioma stem cells utilizing the BIM1 pathway and are characterized by a mesenchymal, inflammatory cell type dependent on glucose metabolism in the absence of oxygen.

«Inhibition of the EZH2 pathway slows growth of tumors in mouse brain derived from glioma stem cells from the enhancing margin of human tumors.

Investigators at Dartmouth have extensive Shared Resources available for research and this team used the Pathology Shared Resource to evaluate cell cycle distribution in the glioma.

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«This is exciting because it's the first animal model of pediatric high - grade gliomas, or malignant brain tumors,» says Maria Castro, Ph.D., senior author of the paper and a professor in the departments of Neurosurgery and Cell and Developmental Biology at U-M.

Reykjavik, ICELAND, 25 September 2011 — Scientists at deCODE Genetics and academic collaborators from Iceland, The Netherlands, Spain, Denmark, Germany, Sweden, the USA, the UK and Romania today report the discovery of a variant in the sequence of the human genome associated with risk of developing basal cell carcinoma of the skin (BCC), as well as prostate cancer and glioma, the most serious form of brain cancer.

Research ROS accumulation and IGF - IR inhibition contribute to fenofibrate / PPARα - mediated inhibition of Glioma cell motility in vitro.

Quantitative analysis of mitotic Olig2 cells in adult human brain and gliomas: implications for glioma histogenesis and biology.

Reber, F., Reber, U. and Funk, R.H. Intracellular changes in astrocytes and NG 108 - 15 neuroblastoma X glioma cells induced by advanced glycation end products.

The key to more effective treatment for glioma is to get to grips with the glioma stem cells, which share many characteristics with the normal neural stem cells in the brain.

We can even engineer glioma genes into normal cells to see how they operate, and vice versa — we can try and «fix» the damaged glioma genes in patient's cells in the dish and see if this brings them back to a normal state.

Gliomas, which originate in glial cells that support and protect neurons, account for about 70 % of brain cancers.

Of great interest, stem - like cells have also been discovered in some cultured cancer cell lines, including glioma (22, 23), ovarian (24, 25), liver (26), and prostate (27 — 29) cancer cells.

They found that the exposed rats were more likely to develop cancers, specifically malignant gliomas — a tumor of glial cells in the brain — and tumors in the heart.

Primary brain tumors (those arising form the cells of the brain and it's lining) in dogs include meningioma, glioma, choroid plexus papilloma, pituitary adenoma or adenocarcinoma, and others.

So far this year, American Veterinarian ® has reported on immunotherapies that may slow growth or even shrink gliomas in dogs and humans, a liquid biopsy assessment tool to detect tumor cell mutation, and a shared study between the American Kennel Club Canine Health Foundation and the V Foundation for Cancer Research on the treatment of bladder cancer.