TFUMseq (Temporal FUnctional Metagenomics sequencing) uses shotgun libraries cloned into a recipient bacterial species, tracked over time
in gnotobiotic mice by deep sequencing and computational methods.
We will leverage this approach, allied to cutting - edge microbiological and immunological techniques
in gnotobiotic mouse models of IBD, to identify and characterize the microbes that contribute to the development and pathogenesis of IBD, and the mechanisms underlying these interactions.
Not exact matches
«The mutation prevention system maintained antibiotic sensitivity not only
in E. coli strains cultured
in standard laboratory conditions but also
in bacteria that were used to colonize the gastrointestinal tract of
gnotobiotic mice.
Control
mice were maintained
in a single cage
in a separate
gnotobiotic isolator.
Mice receiving the library were individually caged
in a
gnotobiotic isolator.
In this study, mice were separately caged in the same gnotobiotic isolator, and we employed meticulous techniques to avoid cross ‐ contaminatio
In this study,
mice were separately caged
in the same gnotobiotic isolator, and we employed meticulous techniques to avoid cross ‐ contaminatio
in the same
gnotobiotic isolator, and we employed meticulous techniques to avoid cross ‐ contamination.
Effects of Intestinal Microbiota on Brain Development
in Humanized
Gnotobiotic Mice — Jing Lu — Scientific Reports
Gnotobiotic and Conventional
Mouse Systems to Support Microbiota Based Studies — Richard Lavin et al. — Current Protocols
in Immunology
[Review] The Role of the Gut Microbiota
in the Metabolism of Polyphenols as Characterized by
Gnotobiotic Mice — Pasinetti, Giulio Mari — Journal of Alzheimer's Disease
Preterm infant gut microbiota affects intestinal epithelial development
in a humanized microbiome
gnotobiotic mouse model.
In the first study of this kind, germ - free (GF), specific pathogen - free (SPF), and gnotobiotic mice were compared in their response to restraint stress [36
In the first study of this kind, germ - free (GF), specific pathogen - free (SPF), and
gnotobiotic mice were compared
in their response to restraint stress [36
in their response to restraint stress [36].
The yeast form of the fungus Candida albicans promotes persistence
in the gut of
gnotobiotic mice — Lena Böhm — PLoS Pathogens
A service to derive germ - free (axenic)
mice is now provided by three infrastructures with a long standing expertise and track record
in the derivation of axenic and
gnotobiotic mice, namely the Gnoto / Axenic Facility of the Instituto Gulbenkian de Ciência, the Karolinska Institutet Core Facility for Germ - free Research, and the CNRS Service Isotechnie of the PHENOMIN - TAAM infrastructure.
The participating INFRAFRONTIER infrastructures are among very few dedicated facilities
in Europe who have the required equipment and expertise to generate germ - free and
gnotobiotic mice.
The HZI will also provide access to laboratory and animal facilities up to BSL3 (including the
gnotobiotic unit) and conventional, modified (e.g. knockout, knock -
in, reporter) and humanised (e.g. immune system)
mice as animal models.