«We were surprised at the extent and complexity of the changes
in the gut microbiota composition,» says Peterson.
Differences
in gut microbiota composition in finishing Landrace pigs with low and high feed conversion ratios — Zhen Tan, Antonie van Leeuwenhoek
«We also found differences
in the gut microbiota composition between those children taking a disease - modifying drug for their disease compared with those who were not.
Not exact matches
In the most recent of these reports (in the latest issue of Science), Dr. Jennifer Wargo, a surgeon and research scientist at M.D. Anderson, along with several dozen colleagues at other institutions, reveal that the composition of a patient's gut microbiota can significantly influence whether he or she responds to an immune checkpoint inhibitor — the type of cancer immunotherapy that releases the emergency brakes in the car analogy abov
In the most recent of these reports (
in the latest issue of Science), Dr. Jennifer Wargo, a surgeon and research scientist at M.D. Anderson, along with several dozen colleagues at other institutions, reveal that the composition of a patient's gut microbiota can significantly influence whether he or she responds to an immune checkpoint inhibitor — the type of cancer immunotherapy that releases the emergency brakes in the car analogy abov
in the latest issue of Science), Dr. Jennifer Wargo, a surgeon and research scientist at M.D. Anderson, along with several dozen colleagues at other institutions, reveal that the
composition of a patient's
gut microbiota can significantly influence whether he or she responds to an immune checkpoint inhibitor — the type of cancer immunotherapy that releases the emergency brakes
in the car analogy abov
in the car analogy above.
Stress plays a huge role
in gut health, altering the
composition of the gastrointestinal
microbiota and likewise, an unhealthy diversity of bacteria can impact emotional behaviour and exacerbate our stress response.
There are other components
in breast milk known to shape the
composition of the
gut microbiota.
A small study of 60 randomly selected 7 - year - old children, 31 delivered by cesarean and 29 delivered vaginally, assessed
microbiota composition by determining fecal
microbiota profiles using culture - independent fluorescent
in situ hybridization and compared the respective effects of delivery mode on
gut microbiota (12).
Over 100 different oligosaccharides have been identified
in the human colon, and recent research has shown that variations
in the oligosaccharides within the mucus are associated with variations
in the
composition of the
gut microbiota.
«Both
in humans and mice there is a correlation between altered
gut microbiota composition and inflammaging, but the link between the two remains to be proven
in humans» concludes Fransen.
«Strategies that are known to alter
gut microbiota composition include changes
in diet, probiotics, and prebiotics.»
Changes
in the
composition of the
gut microbiota are seen
in many human diseases such IBD, a chronic, lifelong inflammatory disorder that includes Crohn's disease and ulcerative colitis.
«Since inflammaging is thought to contribute to many diseases associated with ageing, and we now find that the
gut microbiota plays a role
in this process, strategies that alter the
gut microbiota composition in the elderly could reduce inflammaging and promote healthy ageing,» explains Dr Floris Fransen, who performed the research at the University Medical Center Groningen, The Netherlands.
«Remarkably, our findings suggest that
composition of the
gut microbiota influence and alter central carbon metabolism
in a genotype independent manner.
We know that a well - balanced
gut microbiota is critical for maintaining general health, and alterations
in the
composition of
gut microbiota have been linked to a range of disorders.»
Analyzing the
composition of the
gut microbiota, investigators found that Proteobacteria and Bacteroidetes persisted after the broad - spectrum antibiotic treatment
in the Western diet - fed FXR KO mice.
Researchers observed that consuming emulsifiers drastically changed the species
composition of the
gut microbiota in a manner that made it more pro-inflammatory, creating a niche favoring cancer induction and development.
They observed that emulsifier consumption changed the species
composition of the
gut microbiota and did so
in a manner that made it more pro-inflammatory.
Low - grade inflammation, a condition more prevalent than IBD, was shown to be associated with altered
gut microbiota composition and metabolic disease and is observed
in many cases of colorectal cancer.
In research published last year, Raoult and others showed that the vulnerable subgroups could be predicted by the
composition of their
gut microbiota prior to antibiotic treatment.
Although the patient's residual colonic
microbiota, prior to therapy was deficient
in members of the bacterial divisions - Firmicutes and Bacteriodetes, transplantation had a dramatic impact on the
composition of the patient's
gut microbiota.
OBJECTIVES We aimed at evaluating the
composition of the
gut microbiota in adult patients with T1DM and T2DM and establishing a link between data obtained from microbiological testing and the patients» clinical data.
«We know that antibiotics are major risk factors for C. diff infection because they alter the
gut microbiota, or
composition of bacteria
in the
gut, by eliminating the bacteria that are normally there,» says Casey Theriot, assistant professor of infectious disease at NC State and corresponding author of a paper describing the research.
Review:
Gut Microbiota Contribute to Age - Related Changes
in Skeletal Muscle Size,
Composition, and Function: Biological Basis for a
Gut - Muscle Axis — Gregory J. Grosicki — Calcified Tissue International
Fructose liquid and solid formulations differently affect
gut integrity,
microbiota composition and related liver toxicity: a comparative
in vivo study — Raffaella Mastrocola — Journal of Nutritional Biochemistry
A research conducted
in 2014 discovered that regular consumption of pistachios and almonds may be hugely beneficial for the
composition of
gut microbiota which is defined as «the ecological community of commensal, symbiotic and pathogenic microorganisms that share our body space».
Important functions are provided by
gut microbiota, and modification towards a «beneficial»
composition is a promising approach for intestinal health support, with a potential impact on overall health, and it seems that pistachios could play a part
in this modification.
«There are studies showing that what we eat can alter the
composition and products of the
gut flora —
in particular, that people with high - vegetable, fiber - based diets have a different
composition of their
microbiota, or
gut environment, than people who eat the more typical Western diet that is high
in fat and carbohydrates,» [senior author Dr. Emeran] Mayer said.
The great news is that by adding fermented veggies into your foods, you are changing your
gut health for better: «the
composition of the
gut microbiota has been shown to differ
in lean and obese humans and animals and to change rapidly
in response to dietary factors.
''
Gut microbiota composition,» Increased intestinal permeability,» Imbalance in the enteroendocrine system, and» Perturbed immune system in the g
Gut microbiota composition,» Increased intestinal permeability,» Imbalance
in the enteroendocrine system, and» Perturbed immune system
in the
gutgut.
The delicate balance between the human microbiome and the development of psychopathologies is particularly interesting given the ease with which the microbiome can be altered by external factors, such as diet, 23 exposure to antimicrobials24, 25 or disrupted sleep patterns.26 For example, a link between antibiotic exposure and altered brain function is well evidenced by the psychiatric side - effects of antibiotics, which range from anxiety and panic to major depression, psychosis and delirium.1 A recent large population study reported that treatment with a single antibiotic course was associated with an increased risk for depression and anxiety, rising with multiple exposures.27 Bercik et al. 28 showed that oral administration of non-absorbable antimicrobials transiently altered the
composition of the
gut microbiota in adult mice and increased exploratory behaviour and hippocampal expression of brain - derived neurotrophic factor (BDNF), while intraperitoneal administration had no effect on behaviour.
A study that looked at the mechanism behind dietary fibers effect on the microbiome, they hypothesized that «dietary fiber resists digestion
in the small intestine, and enters the colon where it is fermented to produce [short chain fatty acids] that may enhance the healthy
composition of
gut microbiota.»
In particular, studies have illustrated an association between the
gut microbiota composition and cognitive processes such as learning and memory.
A study published
in May 2015 suggests that alcohol abuse changes the
composition of
gut microbiota.
Since a change
in composition of
gut microbiota is also suggested to be the underlying factor for the development of obesity, it is obvious to link
gut microbiota with the pathogenesis of diabetes.