Your hair — or lack of hair — is the result of a lifelong tug - of - war between activators that wake up, and inhibitors that calm, stem
cells in every hair follicle on your body, according to Cheng - Ming Chuong, M.D., Ph.D., of the University of Southern California (USC).
One lives just under the surface of the skin (sarcoptic mange - see handout «Sarcoptic Mange in Dogs» for more information), while the other
resides in the hair follicles (demodectic mange).
Staph infections start like this: your dog scratches, breaks the skin and the Staph slip in and cause an itchy
infection in the hair follicle called pyoderma.
A further way in which curcumin can promote hair growth is due to the fact that it has been shown to be an activator of Vitamin D receptor
genes in hair follicles.
Other symptoms, such as increased facial hair, can be treated with medications such as Spironolactone (aldactone), which inhibits the testosterone secreted by the body, and also competes for hormone
receptors in the hair follicles.
The MC5R gene is
expressed in the hair follicle glands that produce the oily, waxy substance called sebum that assists in lubrication, water repellency, and thermo - regulation of the skin and hair.
The full readout of what genes are on and off in dermal papilla cells has never been collected before, so researchers now have a new list of thousands of genes to study further that may play key
roles in hair follicle development.
Waxing can also leave little red bumps called folliculitis on the skin, says Shelly Holmstrom, MD, assistant professor of obstetrics and gynecology at the University of South Florida in Tampa, who has seen many clients with folliculitis from bikini waxes: «It happens when bacteria
get in your hair follicles and cause a little localized infection.»
What they did not know in detail is what happens after those stem cells move down to the base, or bulb, of hair follicles and which cells
in the hair follicles produce SCF — or that cells involved in hair shaft creation make the KROX20 protein, he said.
The exact causes of cradle cap are still unknown, but doctors believe it may be caused by an overproduction of
sebum in the hair follicles and oil glands.
Further study showed that the region of human DNA that contained the single nucleotide change associated with blondness specifically affected the expression of KITLG
only in hair follicles.
Still, by identifying the human hairless gene as an important master switch in regulating cell
death in a hair follicle — a discovery that could lead to gene therapies for unwanted hair growth — Christiano emerged as a new star in the field, and a glamorous one.
«It's possible that for male - type balding we may discover a defect in the androgen receptor molecule which
sits in the hair follicles,» says Hoffman.
Stem cells
in hair follicles prove the viability of adult stem cells to not only clone, but also possibly create embryonic stem cells.
But even if it's not known what happens to cause AGA, researchers have done a lot of work to figure out what stem cells are normally
active in the hair follicle.
Lin28a reactivation improved hair regrowth by promoting
anagen in hair follicles and accelerated regrowth of cartilage, bone, and mesenchyme after ear and digit injuries.
In a study, researchers T.W. Fischer MD, U.C. Hipler PhD and P. Elsner MD, found that after eight days
growth in hair follicles was greatest when the follicles were being placed in caffeine solutions.
Salicylic also has anti-inflammatory properties to help with inflamed cystic breakouts that can occur when blockages deep
in the hair follicles rupture beneath the skin.
According to board certified dermatologist Dr. Karyn Grossman, these annoying comedones (the official medical term) are usually caused by a buildup of sebum and
keratin in the hair follicles of skin.
Demodex is a type of mite that is typically found on dogs, and in times of stress or illness, these mites can overgrow on the skin
in the hair follicles causing it to fall out,» said Animal League America Veterinarian, Dr. Erin Carney.
Because the product is
down in the hair follicles, normal bathing or swimming has no significant effect on the duration of efficacy.
Breeds that shed less are less likely to make their owners sneeze because the dander and saliva remain on the hair that
stays in the hair follicle.